Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Takehiro Shoda"'
Publikováno v:
Journal of anesthesia. 27(1):80-87
[Purpose]In this study, we aimed to investigate the effect of morphine on the activation of extracellular signal-regulated kinase (ERK) and nuclear factor-κB (NF-κB), both of which play crucial roles in T-cell activation. [Methods]Human CD3+ T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848c37edd4e5f3f0aba86330d7644b1e
http://hdl.handle.net/2433/172077
http://hdl.handle.net/2433/172077
Publikováno v:
European Journal of Pharmacology. 558:1-6
Although it is known that the expression of proopiomelanocortin, a precursor protein of adrenocorticotropic hormone, can be affected by a variety of drugs, the effects of calcium channel blockers have not been studied. This study examined the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f4e7eb10859705a7a08f4d46c5f88b
https://doi.org/10.1016/j.ejphar.2006.11.038
https://doi.org/10.1016/j.ejphar.2006.11.038
Publikováno v:
Regional Anesthesia and Pain Medicine. 32:60-66
Background and Objectives Corticotropin-releasing hormone (CRH) induces gene expression of proopiomelanocortin, a precursor protein of adrenocorticotropic hormone and β-endorphin, by elevating intracellular cyclic adenosine 3′,5′-monophosphate (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ad8ef2b1fbb2a7b8deb041b545c2df
https://doi.org/10.1097/00115550-200701000-00011
https://doi.org/10.1097/00115550-200701000-00011
Autor:
Keiko Yunoki, Tsutomu Shichino, Hiroshi Tsujikawa, Hiroki Daijyo, Kazuhiko Fukuda, Takehiro Shoda, Hajime Segawa
Publikováno v:
Nihon Shuchu Chiryo Igakukai zasshi. 13:53-56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a316b1c280a1bf251ed66dcc6569353
https://doi.org/10.3918/jsicm.13.53
https://doi.org/10.3918/jsicm.13.53
Autor:
Takehiro Shoda, Kenjiro Mori, Kazuhiko Fukuda, Hitoshi Morikawa, Hiroyuki Mima, Shigehisa Kato
Publikováno v:
Journal of Neurochemistry. 71:2186-2192
To gain insight into the molecular mechanism for nociceptin function, functional coupling of the nociceptin receptor expressed in Chinese hamster ovary (CHO) cells with phospholipase A 2 (PLA 2 ) was examined. In the presence of A23187, a calcium ion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621f1aab5eba67c2d5bfa8f35b952ae4
https://doi.org/10.1046/j.1471-4159.1998.71052186.x
https://doi.org/10.1046/j.1471-4159.1998.71052186.x
Publikováno v:
Anesthesiology. 95:983-989
Background Opioid-induced long-term functional alterations of the nervous system, such as tolerance, addiction, and dependence, conceivably involve changes in gene expression. The authors have previously reported that opioid receptors are functionall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c375f0440854c071c5023b61e7552c4f
https://doi.org/10.1097/00000542-200110000-00030
https://doi.org/10.1097/00000542-200110000-00030
Publikováno v:
Pflügers Archiv. 438:423-426
Opioids have both inhibitory and stimulatory effects on neurotransmitter release. While the inhibitory effect has been ascribed to presynaptic inhibition of Ca2+ channels, the cellular mechanism underlying the stimulatory effect is not clear. In orde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3fa368f9a055b094d85a903a9aa3dd
https://doi.org/10.1007/pl00008091
https://doi.org/10.1007/pl00008091
Autor:
Kenjiro Mori, Hiroyuki Mima, Shigehisa Kato, Kazuhiko Fukuda, Hitoshi Morikawa, Takehiro Shoda
Publikováno v:
Anesthesia & Analgesia. 87:450-455
Naloxone is a widely used opioid antagonist.To analyze the cellular responses induced by naloxone in the absence of opioid agonists, Chinese hamster ovary (CHO) cells, which do not endogenously express the opioid receptors, have been permanently tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86ce8977f43ce85d08c39d52cee0d1b
https://doi.org/10.1097/00000539-199808000-00041
https://doi.org/10.1097/00000539-199808000-00041
Autor:
Kazuhiko Fukuda, Hitoshi Morikawa, Takehiro Shoda, Shigehisa Kato, Hiroyuki Mima, Kenjiro Mori
Publikováno v:
British Journal of Pharmacology. 123:1111-1118
1 To approach the mechanisms underlying desensitization of the opioid receptor-mediated Ca2+ channel inhibition, the effects of prolonged application of [D-Ala2, D-Leu5]enkephalin (DADLE) on Ba2+ currents (IBa) through Ca2+ channels were analysed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c52b3dfb0239130d98eb12a561530398
https://doi.org/10.1038/sj.bjp.0701733
https://doi.org/10.1038/sj.bjp.0701733
Autor:
Maiko, Tominaga, Hidekatsu, Furutani, Hajime, Segawa, Takehiro, Shoda, Hiroyuki, Mima, Takehiko, Adachi, Kazuhiko, Fukuda
Publikováno v:
Masui. The Japanese journal of anesthesiology. 52(7)
Liver transplantation for patients with severe portopulmonary hypertension (PPHTN) has been associated with high mortality. We conducted perioperative management of two patients with severe PPHTN for living-donor liver transplantation. The first case
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1cf67970656761b3f3ba877bc8321114
https://pubmed.ncbi.nlm.nih.gov/12910972
https://pubmed.ncbi.nlm.nih.gov/12910972