Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Takehiro Kado"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The growth and division of mycobacteria, which include clinically relevant pathogens, deviate from that of canonical bacterial models. Despite their Gram-positive ancestry, mycobacteria synthesize and elongate a diderm envelope asymmetricall
Externí odkaz:
https://doaj.org/article/a4ba7c81eb8c40999bca3a5424d305a9
Autor:
Takehiro Kado, Zarina Akbary, Daisuke Motooka, Ian L Sparks, Emily S Melzer, Shota Nakamura, Enrique R Rojas, Yasu S Morita, M Sloan Siegrist
Publikováno v:
eLife, Vol 12 (2023)
Lateral partitioning of proteins and lipids shapes membrane function. In model membranes, partitioning can be influenced both by bilayer-intrinsic factors like molecular composition and by bilayer-extrinsic factors such as interactions with other mem
Externí odkaz:
https://doaj.org/article/0675f9d458954b2ab56fd596e2d3b0f3
Autor:
Malavika Prithviraj, Takehiro Kado, Jacob A. Mayfield, David C. Young, Annie D. Huang, Daisuke Motooka, Shota Nakamura, M. Sloan Siegrist, D. Branch Moody, Yasu S. Morita
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT The intracellular membrane domain (IMD) is a laterally discrete region of the mycobacterial plasma membrane, enriched in the subpolar region of the rod-shaped cell. Here, we report genome-wide transposon sequencing to discover the controller
Externí odkaz:
https://doaj.org/article/071ab252440f496891804f784c00ed5e
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 9, Pp 100262- (2022)
Mycobacteria share an unusually complex, multilayered cell envelope, which contributes to adaptation to changing environments. The plasma membrane is the deepest layer of the cell envelope and acts as the final permeability barrier against outside mo
Externí odkaz:
https://doaj.org/article/c4ef99169e35487eabdf40165c746faa
Autor:
Kohei Yamazaki, Takashige Kashimoto, Takehiro Kado, Yukihiro Akeda, Kazuki Yoshioka, Toshio Kodama, Mai Yamamoto, Masashi Okamura, Tsutomu Kakuda, Shunji Ueno
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 839-847 (2020)
Necrotizing soft tissue infections (NSTI) progress to severe necrosis and result in fatal sepsis within a short time. Vibrio vulnificus is a causative agent and can spread from the initial infection site through soft tissue finally to the systemic ci
Externí odkaz:
https://doaj.org/article/c9bbd95c7c684f50907d2ffa4618575f
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Vibrio vulnificus is known to cause necrotizing soft tissue infections (NSTIs). However, the pathogenic mechanism causing cellulitis, necrotizing fasciitis, muscle necrosis, and rapidly developing septicemia in humans have not been fully elucidated.
Externí odkaz:
https://doaj.org/article/0f5f24dd9e9a447498313685658d319a
Autor:
Takashige Kashimoto, Hiroyuki Sugiyama, Keigo Kawamidori, Kohei Yamazaki, Takehiro Kado, Kaho Matsuda, Toshio Kodama, Takao Mukai, Shunji Ueno
Publikováno v:
BMC Microbiology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Vibrio vulnificus hemolysin (VVH) is a pore-forming toxin secreted by Vibrio vulnificus. Cellular cholesterol was believed to be the receptor for VVH, because cholesterol could bind to VVH and preincubation with cholesterol inhibi
Externí odkaz:
https://doaj.org/article/937a5b7e52e141268e9f71415b6f5097
Autor:
Alam García-Heredia, Takehiro Kado, Caralyn E Sein, Julia Puffal, Sarah H Osman, Julius Judd, Todd A Gray, Yasu S Morita, M Sloan Siegrist
Publikováno v:
eLife, Vol 10 (2021)
Many antibiotics target the assembly of cell wall peptidoglycan, an essential, heteropolymeric mesh that encases most bacteria. In rod-shaped bacteria, cell wall elongation is spatially precise yet relies on limited pools of lipid-linked precursors t
Externí odkaz:
https://doaj.org/article/5e854a09122b4a0eb05a1616a3d7f3aa
Autor:
Kohei Yamazaki, Takashige Kashimoto, Mio Morita, Takehiro Kado, Kaho Matsuda, Moeko Yamasaki, Shunji Ueno
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Vibrio vulnificus can cause severe necrotic lesions within a short time. Recently, it has been reported that the numbers of wound infection cases in healthy hosts are increasing, for which surgical procedures are essential in many instances to elimin
Externí odkaz:
https://doaj.org/article/c77cbe045ee24fef9a0f87f391988c8b
Publikováno v:
Microorganisms, Vol 9, Iss 5, p 934 (2021)
Vibrio vulnificus causes rapid septicemia in susceptible individuals who have ingested contaminated foods or have open wounds exposed to seawater contaminated with the bacteria. Despite antibiotic therapy and aggressive debridement, mortality from se
Externí odkaz:
https://doaj.org/article/ab7b952fe7a849b79b724b783b0c8c58