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pro vyhledávání: '"Takehiko Tsutsumi"'
Autor:
Takehiko Tsutsumi, Yutaka Ebizuka, Yuji Katsube, Ting Xiang, Hong Zhang, Kazuo Masuda, Masaaki Shibuya, Miyuki Otsuka
Publikováno v:
Organic Letters. 8:2835-2838
[structure: see text] Thirteen oxidosqualene cyclase homologues exist in the genome of Arabidopsis thaliana. One of these genes, At4g15340, was amplified by PCR and expressed in yeast. The yeast transformant accumulated tricyclic triterpene, (3S,13R)
Publikováno v:
Pure and Applied Chemistry. 75:369-374
The Arabidopsis thaliana genome-sequencing project has identified the presence of 13 oxidosqualene cyclase homologs in this plant. In addition to the already identified clones, namely, CAS1 cycloartenol synthase, LUP1 lupeol synthase, and YUP8H12R.43
Autor:
Masaki Hoshino, Motoo Shiro, Tetsuo Kushiro, Yutaka Ebizuka, Takehiko Tsutsumi, Masaaki Shibuya, Ken-ichi Kawai
Publikováno v:
Organic letters. 8(24)
Arabidopsis thaliana LUP1 (At1g78970) catalyzes the cyclization of oxidosqualene into lupeol and 3beta,20-dihydroxylupane (lupanediol). The stereochemical course of water addition to the lupanyl cation was studied. The X-ray crystal structure of lupa