Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Takehiko Nishioka"'
Autor:
Gentaro Iribe, Yoichi Goto, Katsuya Hata, Takehiko Nishioka, Akio Saeki, Toshiyuki Takasago, Tad W. Taylor, Satoshi Mohri, Hiroyuki Suga, Junichi Araki, Juichiro Shimizu
Publikováno v:
The Japanese Journal of Physiology. 50:257-265
Caffeine causes a considerable O(2) waste for positive inotropism in myocardium by complex pharmacological mechanisms. However, no quantitative study has yet characterized the mechanoenergetics of caffeine, particularly its O(2) cost of contractility
Autor:
Yasuzo Noguchi, Keiichi Fujiwara, Yasuaki Naito, Yasuhiro Iwasaki, Hiroyoshi Komai, Takehiko Nishioka
Publikováno v:
Surgery Today. 28:1108-1111
Triple-barreled aortic dissection is a rare form of aortic dissection associated with high mortality. We report herein the case of a 41-year-old woman with Marfan's syndrome who developed acute triple-barreled aortic dissection from a Stanford type B
Autor:
Katsuya Hata, Yoichi Goto, Akio Saeki, Osamu Kawaguchi, Hiroyuki Suga, Tad W. Taylor, Toshiyuki Takasago, Takehiko Nishioka
Publikováno v:
The Japanese Journal of Physiology. 47:205-215
The negative inotropism of 2,3-butanedione monoxime (BDM) < or = 5 mmol/l has been attributed primarily to directly suppressed crossbridge force development without much suppressed intracellular Ca2+ handling. However, there is evidence that BDM simu
Autor:
Tad W. Taylor, Toshiyuki Takasago, Hiroyuki Suga, Takehiko Nishioka, Yoichi Goto, Katsuya Hata, Akio Saeki
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 270:H583-H593
Mechanical vibration depresses cardiac contractility. We studied the mechanoenergetic effects of this negative inotropism in the left ventricle (LV) of an isolated, cross-circulated dog heart preparation. We took full advantage of the mechanoenergeti
Publikováno v:
Circulation Research. 74:794-805
Left ventricular (LV) contractile dysfunction during acidosis has been reported to be almost reversible in crystalloid-perfused hearts after correction of acidosis. In contrast, we have found that, in blood-perfused hearts, contractile function is pa
Autor:
Hiroyuki Suga, Osamu Kawaguchi, Toshiyuki Takasago, Takehiko Nishioka, Yoichi Goto, Katsuya Hata, Akio Saeki
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 266:H730-H740
The effect of acidosis on left ventricular (LV) mechanoenergetics was assessed in seven excised, cross-circulated dog hearts with the use of the frameworks of the contractility index (Emax) and the relationship between myocardial oxygen consumption (
Autor:
Q Yoichi Goto, Akio Saeki, Hiroyuki Suga, Katsuya Hata, Toshiyuki Takasago, Takehiko Nishioka, Tad W. Taylor
Publikováno v:
Journal of Biomechanics. 26:1217-1225
Several investigators have found experimentally that the force-time integral varies non-linearly with energy expenditure over the course of a cardiac contraction. Also, recent research findings have indicated that the crossbridge cycle to ATP hydroly
Publikováno v:
Japanese Circulation Journal. 57:1233-1237
Autor:
T W Taylor, Osamu Kawaguchi, Toshiyuki Takasago, Akio Saeki, Shiho Futaki, Yoichi Goto, Katsuya Hata, Hitoshi Yaku, Yuichi Ohgoshi, Takehiko Nishioka
Publikováno v:
Circulation. 86:1291-1301
BACKGROUND We hypothesized that the effect of pimobendan (UD-CG 115 BS) to increase calcium sensitivity of contractile protein might result in less myocardial oxygen consumption (VO2) in comparison with dobutamine when they enhance ventricular contra
Autor:
Osamu Kawaguchi, Akio Saeki, Toshiyuki Takasago, Yoichi Goto, Takehiko Nishioka, Katsuya Hata, Yuichi Ohgoshi, Hitoshi Yaku, Tad W. Taylor, Shiho Futaki, Hiroyuki Suga
Publikováno v:
Heart and Vessels. 7:57-65
We propose new indexes to evaluate the effects of ventricular inotropism and lusitropism on stroke volume. The end-systolic pressure-volume relationship (ESPVR) or its slope (Emax) has been employed to assess ventricular inotropism. The end-diastolic