Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Takehiko Maeda"'
Autor:
Keiko Ueno, Norikazu Kiguchi, Yuka Kobayashi, Fumihiro Saika, Naoki Wakida, Chizuko Yamamoto, Takehiko Maeda, Masanobu Ozaki, Shiroh Kishioka
Publikováno v:
Journal of Pharmacological Sciences, Vol 124, Iss 1, Pp 47-53 (2014)
Abstract.: We previously reported that nicotine (NIC)-induced analgesia was elicited in part by activation of the endogenous opioid system. Moreover, it is well known that NIC has physical-dependence liability, but its mechanism is unclear. Therefore
Externí odkaz:
https://doaj.org/article/4fe0650f831b4635ab9ffc89eee53047
Publikováno v:
Journal of Pharmacological Sciences, Vol 123, Iss 4, Pp 301-305 (2013)
Neuropathic pain, which is intolerable and persistent, arises as a direct consequence of a lesion or disease affecting the somatosensory system and can be debilitating for the affected patients. Accumulating evidence from animal studies has revealed
Externí odkaz:
https://doaj.org/article/ae00ec415fa64fdf9f891daf28f222a3
Publikováno v:
Journal of Pharmacological Sciences, Vol 108, Iss 3, Pp 341-347 (2008)
To clarify the role of peroxisome proliferator activated receptor γ (PPARγ) in neuropathic pain, we examined the effect of pioglitazone, a PPARγ agonist, on tactile allodynia and thermal hyperalgesia in a neuropathic pain model. Mice were subjecte
Externí odkaz:
https://doaj.org/article/d4baf98855f94e42b6dbaed330d4cd9e
Autor:
Wakako Hamabe, Takehiko Maeda, Norikazu Kiguchi, Chizuko Yamamoto, Shogo Tokuyama, Shiroh Kishioka
Publikováno v:
Journal of Pharmacological Sciences, Vol 105, Iss 4, Pp 353-360 (2007)
It is known that opioid analgesics given systemically have limited distribution into the brain because of their interaction with P-glycoprotein (P-gp), an ATP-dependent efflux pump acting at the blood-brain barrier (BBB). We previously found that mor
Externí odkaz:
https://doaj.org/article/1ba7ce9ca3d448f796c6a9c8ca716a90
Autor:
Yohji Fukazawa, Takehiko Maeda, Norikazu Kiguchi, Kazuo Tohya, Michio Kimura, Shiroh Kishioka
Publikováno v:
Journal of Pharmacological Sciences, Vol 104, Iss 2, Pp 159-166 (2007)
We previously demonstrated that electroacupuncture (EA) stimulation both produced antinociception and attenuated intrathecal (i.t.) morphine analgesia, suggesting that EA is capable of inducing two opposing systems, that is, opioid and anti-opioid me
Externí odkaz:
https://doaj.org/article/552aecffdad34aae8369dec56a213724
Autor:
Yohji Fukazawa, Takehiko Maeda, Wakako Hamabe, Kazumasa Kumamoto, Yuan Gao, Chizuko Yamamoto, Masanobu Ozaki, Shiroh Kishioka
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 4, Pp 408-414 (2005)
We evaluated the interaction between electroacupuncture (EA)-induced antinociception and an endogenous anti-analgesic system. EA was applied to the ST-36 acupoint for 45 min in male Sprague-Dawley rats, and pain thresholds were assessed by the hind-p
Externí odkaz:
https://doaj.org/article/9fb1a0dbad614d329ea71d7d3c9c190d
Autor:
Norifumi Shimizu, Shiroh Kishioka, Takehiko Maeda, Yohji Fukazawa, Chizuko Yamamoto, Masanobu Ozaki, Hiroyuki Yamamoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 94, Iss 3, Pp 240-245 (2004)
The present study was designed to investigate the pharmacokinetic interaction of morphine with three classes of L-type calcium channel blockers (CCB) and its relationship to morphine-induced mechanical antinociception in mice. The CCB classes were be
Externí odkaz:
https://doaj.org/article/c47d0d5179d940368fdc86ea66916cca
Autor:
Norifumi Shimizu, Shiroh Kishioka, Takehiko Maeda, Yohji Fukazawa, Yoshihiro Dake, Chizuko Yamamoto, Masanobu Ozaki, Hiroyuki Yamamoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 95, Iss 4, Pp 452-457 (2004)
Morphine’s analgesic actions are thought to be mediated through both the central and peripheral nervous systems. L-type calcium channel blockers have been reported to potentiate the analgesic effects of morphine, but the locus of this interaction i
Externí odkaz:
https://doaj.org/article/de2aa110562b41a5a1c36c216ae21131
Autor:
Takehiko Maeda
Publikováno v:
Journal of Environmental Conservation Engineering. 48:260-264
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c579eadd404d4130d2088ff961287807
https://doi.org/10.5956/jriet.48.5_260
https://doi.org/10.5956/jriet.48.5_260
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3d49bb482a082804678feb4f476f518
https://doi.org/10.1254/jpssuppl.95.0_2-p-129
https://doi.org/10.1254/jpssuppl.95.0_2-p-129