Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Takehiko, Iida"'
Publikováno v:
The Journal of organic chemistry. 64(14)
Publikováno v:
Masui. The Japanese journal of anesthesiology. 65(2)
We compared three combined spinal-epidural anesthesia (CSEA) techniques for cesarean delivery. Hypotension, nausea and vomiting are main problems produced by coonventional intrathecal doses. These problems were our secondary observations. Our primary
Publikováno v:
Chemical and Pharmaceutical Bulletin. 50:530-533
An improved synthesis of 3-beta-D-ribofuranosylwybutine (2) has been achieved by the Wittig reaction between 4,6-dimethyl-9-oxo-3-[2,3,5-tris-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-4,9-dihydro-3H-imidazo[1,2-a]-purine-7-carbaldehyde (8) an
Autor:
Robert A. Reamer, Satake Nobuya, Steven A. Weissman, Atsushi Akao, Asayuki Kamatani, Masashi Kawasaki, Ralph P. Volante, Toshiaki Mase, David M. Tschaen, Takayuki Nemoto, Kai Rossen, Takehiko Iida, Petrillo Daniel E, Shouichi Hiraga
Publikováno v:
Tetrahedron. 57:8917-8923
DNA topoisomerase I inhibitors are currently under investigation as cancer chemotherapy agents of which indolocarbazole glycoside ( 1 ) has been identified as a promising candidate. A practical, scalable synthesis of 1 that limits the isolation of cy
Autor:
David M. Tschaen, Thoa Hoang, Yoshiaki Kato, Atsushi Akao, Joseph J. Lynch, Audrey Molina, Takayuki Nemoto, Koji Tomimoto, Ralph P. Volante, Toshiaki Mase, Daniel Zewge, Fengrui Lang, Paul J. Reider, Takehiko Iida, Toshihiro Wada, Keisuke Kamei, Shinji Kato, Jaemoon Lee, Takahiro Itoh, Ilias Dorziotis, Peter E. Maligres, Khateeta M. Emerson, Shigemitsu Okada, Masashi Kawasaki, Jake Z. Song, Ioannis N. Houpis, Robert A. Reamer
Publikováno v:
The Journal of Organic Chemistry. 66:6775-6786
An efficient synthesis of a structurally unique, novel M(3) antagonist 1 is described. Compound 1 is conveniently disconnected retrosynthetically at the amide bond to reveal the acid portion 2 and the amine fragment 3. The synthesis of key intermedia
Publikováno v:
Tetrahedron Letters. 42:4841-4844
Lithium tributylmagnesate complex (n-Bu3MgLi), readily prepared from n-BuLi and n-BuMgCl (2:1), is a novel metallation agent. It is quite efficient for the selective mono-bromine–magnesium exchange of 2,6-dibromopyridine ( 1 ) under non-cryogenic c
Autor:
Masakatsu Shibasaki, Erasmus M. Vogl, and Kentaro Yamaguchi, Jochen Roels, Shigeki Matsunaga, Jagattaran Das, Takehiko Iida, Noriyoshi Yamamoto
Publikováno v:
Journal of the American Chemical Society. 122:2252-2260
The catalytic enantioselective meso-epoxide ring opening reaction with phenolic oxygen nucleophile (4-methoxyphenol) is described for the first time herein. This reaction was first found to be promoted by (R)-GaLB (Ga = gallium, L = lithium, B = (R)-
Publikováno v:
Tetrahedron. 55:8857-8867
The direct catalytic asymmetric Mannich reaction of unmodified ketones is described. This was achieved by the cooperative catalysis of a heterobimetallic asymmetric complex: AlLibis(binaphthoxide) (ALB) and La(OTf)3·nH2O in the presence of molecular
Publikováno v:
Tetrahedron Letters. 40:307-310
The first example of a direct catalytic asymmetric Mannich-type reaction using unmodified ketones and an aminomethyl ether is described. This was achieved by the cooperative catalysis of a heterobimetallic asymmetric complex (AlLibis(binaphthoxide))
Publikováno v:
Tetrahedron Letters. 39:7917-7920
The synthesis of new C 2 -symmetric chiral ligands consisting of two binaphthol units linked by a short bridge is described. These ligands can be used for investigating catalytic asymmetric reactions which utilize BINOL or related ligands as was demo