Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Takehide Murata"'
Autor:
Ichinosuke Hyodo, Takehide Murata, Kazunari K. Yokoyama, Naoyuki Hasegawa, Yuichi Obata, Kiminori Nakamura, Mariko Wakayama, Rei Kawashima, Masato Abei, Hiroyuki Mizuguchi, Kuniaki Fukuda, Hirofumi Hamada, Emiko Seo
Publikováno v:
International Journal of Cancer. 129:1244-1253
A critical issue in adenovirus (Ad)-based cancer gene therapy is to improve the specificity of gene delivery to cancer cells for better efficacy and safety. We explored methods of retargeting Ad vectors for selective gene therapy of human biliary can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813a58ad6c39bf5152832994c594cd9e
https://doi.org/10.1002/ijc.25758
https://doi.org/10.1002/ijc.25758
Autor:
Shigeharu Wakana, Yuichi Obata, Kaoru Fukami-Kobayashi, Satoshi Takahashi, Koji Doi, Yoshiki Mochizuki, Kouji Kozaki, Tetsuro Toyoda, Yuko Makita, Manabu Ishii, Nobuhiko Tanaka, Terue Takatsuki, Teiichi Furuichi, Atsushi Hijikata, Atsushi Yoshiki, Koro Nishikata, Yukio Nakamura, Yuko Yoshida, Hiroshi Masuya, Yoshihide Hayashizaki, Takehide Murata, Hideya Kawaji, Riichiro Mizoguchi, Kazunori Waki, Subburaman Mohan, Norio Kobayashi, Osamu Ohara, Akihiro Matsushima
Publikováno v:
Nucleic Acids Research
The RIKEN integrated database of mammals (http://scinets.org/db/mammal) is the official undertaking to integrate its mammalian databases produced from multiple large-scale programs that have been promoted by the institute. The database integrates not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96707a13c7fce07999ef2c66679414e
https://doi.org/10.1093/nar/gkq1078
https://doi.org/10.1093/nar/gkq1078
Autor:
Narumi Ogonuki, Michiko Hirose, Kazunari K. Yokoyama, Masanori Hatori, Tadashi Sankai, Atsuo Ogura, Hiroyuki Miyoshi, Nobuhiro Shimozawa, Kazufumi Katayama, Megumi Hirose, Natsumi Shimizu, Takehide Murata, Noriko Wakisaka, Arata Honda, Hiromi Miki, Kimiko Inoue
Publikováno v:
Reproductive BioMedicine Online. 17:706-715
Although embryonic stem (ES) cell lines derived from mice and primates are used extensively, the development of such lines from other mammals is extremely difficult because of their rapid decline in proliferation potential and pluripotency after seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2cacf978885ce30b5952900e642ddf
https://doi.org/10.1016/s1472-6483(10)60320-3
https://doi.org/10.1016/s1472-6483(10)60320-3
Autor:
Hideyo Ugai, Kazunari K. Yokoyama, Takehide Murata, Mizuho Iwama, Koji Nakade, H Li, Jianzhi Pan, S Itohara, Atsushi Yoshiki, B Liu, Makoto Kimura, Yuichi Obata
Publikováno v:
Cell Death & Differentiation. 14:1398-1405
Among the events that control cellular differentiation, the acetylation of histones plays a critical role in the regulation of transcription and the modification of chromatin. Jun dimerization protein 2 (JDP2), a member of the AP-1 family, is an inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a0c947d6033b39045c64ff57ac0e2a
https://doi.org/10.1038/sj.cdd.4402129
https://doi.org/10.1038/sj.cdd.4402129
Autor:
Takehide Murata, Bingbing Liu, Hatsumi Nakata, Jianzhi Pan, Megumi Hirose, Izumu Saito, Sanae Inamoto, Hideyo Ugai, Kazunari K. Yokoyama, Yukari Kujime, Koji Nakade, Erika Suzuki, Makoto Kimura, Yoshinori Nagamura, Kumiko Inabe, Yoshihiro Ugawa, Takahito Yamasaki, Hirofumi Hamada, Yuichi Obata, Miho Terashima
Publikováno v:
The Journal of Gene Medicine. 7:1148-1157
Background Viral vectors are required as gene-delivery systems for gene therapy and basic research. Recombinant adenoviruses (rAds) expressing genes of interest are being developed as research tools and many studies in vitro and in vivo have already
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616e5e7d7435be5fad8f2e0f6d65289c
https://doi.org/10.1002/jgm.786
https://doi.org/10.1002/jgm.786
Autor:
Hong Tang, Yuichi Obata, Miho Terashima, Hideyo Ugai, Makoto Kimura, Takehide Murata, Jianzhi Pan, Kazunari K. Yokoyama, Megumi Hirose, Yukari Kujime, Bingbing Liu, Mujun Zhao, Kumiko Inabe, Takahito Yamasaki, Hirofumi Hamada
Publikováno v:
Biochemical and Biophysical Research Communications. 331:1053-1060
Adenoviruses are excellent vectors for gene transfer and are used extensively for high-level expression of the products of transgenes in living cells. The development of simple and rapid methods for the purification of stable infectious recombinant a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53fb00f8085cecffae6cb1aa80887d4e
https://doi.org/10.1016/j.bbrc.2005.03.227
https://doi.org/10.1016/j.bbrc.2005.03.227
Autor:
Emiko, Seo, Masato, Abei, Mariko, Wakayama, Kuniaki, Fukuda, Hideyo, Ugai, Takehide, Murata, Takeshi, Todoroki, Yasushi, Matsuzaki, Naomi, Tanaka, Hirofumi, Hamada, Kazunari K, Yokoyama
Publikováno v:
Cancer Research. 65:546-552
In order to enhance the efficacy of conditionally replicating adenoviruses (CRAd) in the treatment of cancers of the biliary tract, we studied the efficacy in vitro and in vivo of AxE1CAUP, a CRAd vector that carries a gene for uracil phosphoribosylt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd4f8d5c0b1c13ae074730ffac1f248
https://doi.org/10.1158/0008-5472.546.65.2
https://doi.org/10.1158/0008-5472.546.65.2
Autor:
Kumiko Inabe, Erika Suzuki, Takehide Murata, Hirofumi Hamada, Hideyo Ugai, Kazunari K. Yokoyama
Publikováno v:
Biochemical and Biophysical Research Communications. 300:448-456
Infectious recombinant adenovirus (rAd) is usually produced in human embryonic kidney 293 cells that harbor the E1 gene and rAd has been shown to be an efficient tool for gene transfer both in vivo and in vitro. It also has considerable potential in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02280395df95087f77cdfbbd11655dc
https://doi.org/10.1016/s0006-291x(02)02852-8
https://doi.org/10.1016/s0006-291x(02)02852-8
Autor:
Hideyo Ugai, Takehide Murata, Kazunari K. Yokoyama, Akira Minamihashi, Yuichi Obata, Kahori Kurosaka, Shigeo Saito, Ken Sawai, Yusuke Yamamoto, Yoshiro Kobayashi
Publikováno v:
FEBS Letters. 531:389-396
Embryonic stem (ES) cells are pluripotent cells with the potential capacity to generate any type of cell. We describe here the isolation of pluripotent ES-like cells from equine blastocysts that have been frozen and thawed. Our two lines of ES-like c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13d4234b8cd25e96d1994dacac8e4777
https://doi.org/10.1016/s0014-5793(02)03550-0
https://doi.org/10.1016/s0014-5793(02)03550-0
Publikováno v:
European Journal of Biochemistry. 269:2961-2970
The Sp family is a family of transcription factors that bind to cis-elements in the promoter regions of various genes. Regulation of transcription by Sp proteins is based on interactions between a GC-rich binding site (GGGCGG) in DNA and C-terminal z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fba3c158243d1cac00c10dff6896c351
https://doi.org/10.1046/j.1432-1033.2002.02972.x
https://doi.org/10.1046/j.1432-1033.2002.02972.x