Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Takeharu Ogura"'
Publikováno v:
International Journal of Oncology
Docetaxel is a useful chemotherapeutic agent for the first-line treatment of hormone-refractory prostate cancer. Abnormal expression of Bcl-2 is commonly found in cancer cells, which increases their anti-apoptotic potency and chemo-resistance. We inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c4bd73fce4bde7ea8db9b44e8479e5
http://europepmc.org/articles/PMC4864052
http://europepmc.org/articles/PMC4864052
Publikováno v:
Analytical biochemistry. 508
We developed a technique for the measurement of surface plasmon resonance (SPR) to detect interactions of anti-tumor necrosis factor (TNF) agents with transmembrane TNF-α (mTNF-α) on living whole cells. The injection of a suspension of mTNF-α expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4440857741e2d281912e9f5958a25571
https://pubmed.ncbi.nlm.nih.gov/27349512
https://pubmed.ncbi.nlm.nih.gov/27349512
Autor:
Tetsushi Nakata, Tomoko Namikawa, Yoshiyuki Tanaka, Hirofumi Kataoka, Takeharu Ogura, Yoshikazu Ohtsubo
Publikováno v:
The Journal of Toxicological Sciences. 32:57-67
Inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase occasionally cause myopathy characterized by weakness, pain, and elevated serum creatine phosphokinase (CK). In this study, we investigated the effects of simvastatin, an HMG-CoA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb2c2858b3cc17b0c4c40dd8b78a143
https://doi.org/10.2131/jts.32.57
https://doi.org/10.2131/jts.32.57
Autor:
Seishiro Marukawa, Takeharu Ogura, Katsushi Hosohara, Haruyasu Ueda, Shin-ichiro Kashiwamura, Haruki Okamura, Takako Yano
Publikováno v:
Clinical and Vaccine Immunology. 9:777-783
We investigated the acute hematological changes caused by interleukin-18 (IL-18) in mice. Intraperitoneal administration of IL-18 (2 μg/mouse) resulted in biphasic decreases in the number of leukocytes in the blood. The first phase of decrease occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae79318387c89076543fa175935c849
https://doi.org/10.1128/cdli.9.4.777-783.2002
https://doi.org/10.1128/cdli.9.4.777-783.2002
Autor:
Kiyoshi Takeda, Yoichiro Iwakura, Takeharu Ogura, Tomohiro Yoshimoto, Shizuo Akira, Kenji Nakanishi, Kazunobu Ohkusu, Shin-ichiro Kashiwamura, Haruki Okamura
Publikováno v:
Infection and Immunity. 68:2449-2456
Interleukin-18 (IL-18) is a proinflammatory cytokine that plays an important role in natural killer cell activation and the T helper 1 (Th1) cell response, particularly in collaboration with IL-12. Since Th1 cells play a pivotal role in the host defe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479828d1117b67ce782b60fbf0c7cc20
https://doi.org/10.1128/iai.68.5.2449-2456.2000
https://doi.org/10.1128/iai.68.5.2449-2456.2000
Autor:
Ken-ichi Fujita, Yasutsuna Sasaki, Hiromu Toyoda, Yoshiyuki Tanaka, Takashi Yoshimura, Takeharu Ogura, Tomoyuki Okabe
Publikováno v:
Journal of Bioequivalence & Bioavailability.
SW651K, a fixed combination of tegafur (FT), 5-chloro-2,4-dihydroxypyridine (CDHP) and potassium oxonate (Oxo), is a generic preparation of S-1, which is widely used to treat gastric cancer in Japan. There is little detailed information of pharmacolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9b3e8606960c7cad2cae03de1172ff9
https://doi.org/10.4172/jbb.1000279
https://doi.org/10.4172/jbb.1000279
Autor:
Haruyasu Ueda, Atsuo Sekiyama, Haruki Okamura, Naomi Gamachi, Takeharu Ogura, Shin-ichiro Kashiwamura
Publikováno v:
Cytokine. 33(4)
Treatment of Nylon wool-passed cells (NWC) prepared from the spleen of C57BL/6 mice with IL-18 and IL-12, but not with IL-18 alone, resulted in induction of IFN-gamma, a Th1 cytokine, and GM-CSF at 24 h, and IL-13, a Th2 cytokine at 72 h. The inducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a9e74389529f0ff0d0e56fd7505bcc
https://pubmed.ncbi.nlm.nih.gov/16549365
https://pubmed.ncbi.nlm.nih.gov/16549365
Autor:
Yuki Nagata, Katsushi Hosohara, Haruki Okamura, Shin-ichiro Kashiwamura, Risa Tsuji, Haruyasu Ueda, Takeharu Ogura
Publikováno v:
Blood. 98(7)
Because interleukin-18 (IL-18) is similar to IL-1 and is known to be involved in the hematopoietic progenitor cell growth, the effect of IL-18 on circulating cell populations was examined. Repeated administration of IL-18 induced significant amounts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b0f193924f117b85b2da2e329bca26
https://pubmed.ncbi.nlm.nih.gov/11567996
https://pubmed.ncbi.nlm.nih.gov/11567996
Publikováno v:
International Journal of Oncology; Jun2016, Vol. 48 Issue 6, p2330-2338, 9p
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461376927
Reports from a number of laboratories have demonstrated that UV-irradiation can cause protein damage in the ocular lens and the inactivation of lens enzymes (Li et al., 1990; Zigman et al., 1991; Rafferty et al., 1993; Hightower, 1995). Glycation-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e8c903e359a9f3571bd572e44f6e93d
https://doi.org/10.1007/978-1-4615-5871-2_60
https://doi.org/10.1007/978-1-4615-5871-2_60
