Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Takeharu Nishimoto"'
Publikováno v:
Genes to Cells. 13:571-582
Snf2SR, a suppressor of rna1(ts), which is a temperature-sensitive mutation in Schizosaccharomyces pombe RanGAP (GTPase activating protein), possesses both the SNF2 and the helicase domains conserved in the chromatin remodeling SNF2 ATPase/helicase p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7b4140e2479d8173360abb6dd28be7
https://doi.org/10.1111/j.1365-2443.2008.01190.x
https://doi.org/10.1111/j.1365-2443.2008.01190.x
Autor:
Naoyuki Hayashi, Ken Ichi Yamamoto, Seishi Murakami, Masahiko Kobayashi, Takeharu Nishimoto, Hiroko Shimizu
Publikováno v:
Biochemical and Biophysical Research Communications. 363(3):788-794
The Ran GTPase system regulates the direction and timing of several cellular events, such as nuclear-cytosolic transport, centrosome formation, and nuclear envelope assembly in telophase. To gain insight into the Ran system's involvement in chromatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16841d3f94f949e0510ee70085751df0
http://hdl.handle.net/2297/7371
http://hdl.handle.net/2297/7371
Autor:
Naoyuki Hayashi, Zen ichiro Nagaura, Masahiko Kobayashi, Masaya Oki, Ken Ichi Yamamoto, Hideo Nishitani, Hiroko Shimizu, Takeharu Nishimoto, Susumu Tsurusaki, Seishi Murakami
Publikováno v:
Biochemical and Biophysical Research Communications. 353:330-336
RanGTPase is involved in many cellular processes. It functions in nuclear-cytosolic transport and centrosome formation. Ran also localizes to chromatin as RCC1 does, its guanine nucleotide exchange factor, but Ran's function on chromatin is not known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba53bb2af22942466e9e07cc355471b
https://doi.org/10.1016/j.bbrc.2006.12.028
https://doi.org/10.1016/j.bbrc.2006.12.028
Publikováno v:
Nucleic Acids Research
Previously, we described a novel nucleolar protein, NOP132, which interacts with the small GTP binding protein RRAG A. To elucidate the function of NOP132 in the nucleolus, we identified proteins that interact with NOP132 using mass spectrometric met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd63b67ace95c79c4c2d729babaecb3c
http://europepmc.org/articles/PMC1636366
http://europepmc.org/articles/PMC1636366
Autor:
Kei-ichi Shibahara, Hideo Nishitani, Takeharu Nishimoto, Ayumi Kusano, Jun-ichi Nakayama, Hitoshi Nishijima, Tomoko Yoshioka
Publikováno v:
Molecular Biology of the Cell. 17:2524-2536
Although the Ran GTPase-activating protein RanGAP mainly functions in the cytoplasm, several lines of evidence indicate a nuclear function of RanGAP. We found that Schizosaccharomyces pombe RanGAP, SpRna1, bound the core of histone H3 (H3) and enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc9799aeb8d5bf83acff75db8d11b37
https://doi.org/10.1091/mbc.e05-09-0893
https://doi.org/10.1091/mbc.e05-09-0893
Autor:
Keiichi I. Nakayama, Keiko Nakayama, Toshiki Tsurimoto, Masatoshi Fujita, Masafumi Saijo, Hideo Nishitani, Vassilis Roukos, Yohsuke Nakanishi, Nozomi Sugimoto, Chikashi Obuse, Takeharu Nishimoto, Zoi Lygerou
Publikováno v:
The EMBO Journal. 25:1126-1136
Replication licensing is carefully regulated to restrict replication to once in a cell cycle. In higher eukaryotes, regulation of the licensing factor Cdt1 by proteolysis and Geminin is essential to prevent re-replication. We show here that the N-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c830f448df19aea517b7f643e29744
https://doi.org/10.1038/sj.emboj.7601002
https://doi.org/10.1038/sj.emboj.7601002
Autor:
Eiji Hirose, Mari Mukai, Takeharu Nishimoto, Yosaburo Shibata, Hideo Nishitani, Atsushi Shimada
Publikováno v:
Genes to Cells. 11:29-46
RCC1, a conserved chromosomal protein with a seven-bladed propeller is a GDP/GTP nucleotide exchange factor for RanGTPase that mediates various cellular events. We isolated 16 temperature-sensitive (ts) mutants of S. pombeRCC1-homolog, pim1+, by erro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22c6948f07afc9298a62e59a7da0e1de
https://doi.org/10.1111/j.1365-2443.2005.00919.x
https://doi.org/10.1111/j.1365-2443.2005.00919.x
Autor:
Yonggang Wang, Kosuke Tashiro, Nobutaka Nakashima, Takeshi Sekiguchi, Yuko Todaka, Takeharu Nishimoto
Publikováno v:
Genetics. 170:1515-1524
Yeast Gtr1p and its human homolog RRAG A belong to the Ras-like small G-protein superfamily and genetically interact with RCC1, a guanine nucleotide exchange factor for Ran GTPase. Little is known regarding the function of Gtr1p. We performed yeast t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf5cdad6b57c7f7bbdead477223f979
https://doi.org/10.1534/genetics.105.042366
https://doi.org/10.1534/genetics.105.042366
Publikováno v:
Traffic. 6:502-517
In this article, we identify a cold-sensitive mutant of Xpo1p designated as xop1-2 (but will be referred to from here on as xpo1-ok) that is synthetically lethal with srm1-1, a Saccharomyces cerevisiae RCC1 homolog. xpo1-ok was a novel mutated allele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eb847a3225931c4676e80652c69233a
https://doi.org/10.1111/j.1600-0854.2005.00295.x
https://doi.org/10.1111/j.1600-0854.2005.00295.x
Publikováno v:
Molecular Biology of the Cell. 15:4960-4970
We isolated 11 independent temperature-sensitive (ts) mutants of Schizosaccharomyces pombe RanGAP, SpRna1 that have several amino acid changes in the conserved domains of RanGAP. Resulting Sprna1ts showed a strong defect in mitotic chromosome segrega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4071d3e4aba3986051ae379127cd5e4b
https://doi.org/10.1091/mbc.e04-01-0067
https://doi.org/10.1091/mbc.e04-01-0067