Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Takefumi Onodera"'
Autor:
Sonoko Atsumi, Chisato Nosaka, Takefumi Onodera, Hayamitsu Adachi, Takumi Watanabe, Manabu Kawada, Masabumi Shibuya, Se In Park, Ho Jeong Kwon
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1197 (2024)
We have previously identified Ertredin (3-(2-amino-5-bromophenyl) quinoxalin-2(1H)-one) as a compound that suppresses 3D spheroid formation and tumorigenesis in NIH3T3 cells induced by Epidermal Growth Factor Receptor variant III (EGFRvIII) transduct
Externí odkaz:
https://doaj.org/article/55d6c9f20a1c4ffa949fe7bc10239797
Autor:
Rémi Dulermo, Takefumi Onodera, Geneviève Coste, Fanny Passot, Murielle Dutertre, Martine Porteron, Fabrice Confalonieri, Suzanne Sommer, Cécile Pasternak
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124358 (2015)
Here, we have developed an extremely efficient in vivo Tn5-based mutagenesis procedure to construct a Deinococcus radiodurans insertion mutant library subsequently screened for sensitivity to genotoxic agents such as γ and UV radiations or mitomycin
Externí odkaz:
https://doaj.org/article/3c9ffd09d01e4f089af7fdfc7a7eadca
Autor:
Shun-ichi Ohba, Hayamitsu Adachi, Takefumi Onodera, Manabu Kawada, Ryuichi Sawa, Yohko Yamazaki, Isao Momose
Publikováno v:
The Journal of Biological Chemistry
Large regions in tumor tissues, particularly pancreatic cancer, are hypoxic and nutrient-deprived because of unregulated cell growth and insufficient vascular supply. Certain cancer cells, such as those inside a tumor, can tolerate these severe condi
Autor:
Masatomi Iijima, Masayuki Igarashi, Hayamitsu Adachi, Manabu Kawada, Takefumi Onodera, Yohko Yamazaki, Isao Momose, Ryuichi Sawa, Yumiko Kubota, Hiroyasu Doi
Publikováno v:
Journal of Natural Products. 82:1120-1127
Leucinostatin Y, a new peptaibiotic, was isolated from the culture broth of the entomoparasitic fungus Purpureocillium lilacinum 40-H-28. The planar structure was elucidated by detailed analysis of its NMR and MS/MS data. The absolute configurations
Publikováno v:
International Journal of Oncology. 48:1145-1154
We purified and identified eight xanthones from mangosteen (Garcinia mangostana L.) and investigated whether these compounds inhibited the activities of mammalian DNA polymerases (Pols) and human DNA topoisomerases (Topos). β-Mangostin was the stron
Publikováno v:
Molecular Medicine Reports. 12:5857-5864
A number of naturally occurring agents are hypothesized to protect against ultraviolet (UV)‑induced skin damage. The present study screened >50 plant extracts for inhibitors of UVB‑induced cytotoxicity, using cultured normal human epidermal kerat
Autor:
Takefumi Onodera, Yuka Sakamoto, Yoshiyuki Mizushina, Kazunori Tsubaki, Hideaki Naganune, Atsushi Tabata, Kouji Kuramochi, Moe Kawamura, Isoko Kuriyama
Publikováno v:
Archives of Biochemistry and Biophysics. 573:100-110
We previously found that vitamin K3 (menadione, 2-methyl-1,4-naphthoquinone) inhibits the activity of human mitochondrial DNA polymerase (pol) γ. In this study, we focused on plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone), and chemically synthesi
Autor:
Hideki Ichikawa, Takefumi Onodera, Yuka Sakamoto, Yoshiyuki Mizushina, Tooru Andoh, Eibai Lee-Hiraiwa, Isoko Kuriyama
Publikováno v:
International Journal of Molecular Medicine. 35:1720-1728
The polyphenolic compound, curcumin, is a natural yellow pigment component of turmeric. It exerts various biological effects, such as anti-inflammatory effects, and we have previously demonstrated that curcumin is a specific inhibitor of DNA polymera
Autor:
Takefumi Onodera1, Isao Momose1, Hayamitsu Adachi1, Yohko Yamazaki1, Ryuichi Sawa2, Shun-ichi Ohba1, Manabu Kawada1
Publikováno v:
Journal of Biological Chemistry. 12/4/2020, Vol. 295 Issue 49, p16678-16690. 13p.
Autor:
Takefumi Onodera, Isoko Kuriyama, Yoshiaki Ogawa, Yoshiyuki Mizushina, Shu Nishikori, Shinji Kamisuki, Fumio Sugawara, Yuka Sakamoto
Publikováno v:
Journal of Agricultural and Food Chemistry. 62:7779-7786
The components adsorbed onto activated charcoal following the fermentation process of the Japanese rice wine "sake" have been studied with the aim of identifying suitable applications for this industrial food waste product. The absorbed materials wer