Výsledky vyhledávání - "Takefumi Nojiri"

Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine–endothelial cell interactions

Autor: Takefumi Nojiri, Ichiro Manabe, Yasushi Imai, Daiji Kawanami, Ryozo Nagai, Kazunori Utsunomiya, Tomohiro Harada, Koji Maemura, Norihiko Takeda

Publikováno v: Biochemical and Biophysical Research Communications. 314:415-419

Resistin is an adipocytokine which plays a role in the development of insulin resistance. In this study, we investigated the direct effect of resistin on vascular endothelial cells. Resistin induced the expression of adhesion molecules such as VCAM-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ff8eae05ab90d89f92717c1beb7dab
https://doi.org/10.1016/j.bbrc.2003.12.104

Zobrazit plný text záznamu

Development of a Pioneering Clinical Support System Utilizing Information Technology: Clinical Informatics and Genome Analysis

Autor: Tadashi Yamazaki, Tsutomu Yamazaki, Ryozo Nagai, Doubun Hayashi, Takefumi Nojiri, Koshiro Monzen, Yasushi Imai, Hideo Fujita, Tomohiro Harada, Hiroyuki Morita

Publikováno v: Japanese Heart Journal. 45:315-324

Nowadays, evidence-based medicine has entered the mainstream of clinical judgement and the human genome has been completely decoded. Even the concept of individually designed medicine, that is, tailor-made medicine, is now being discussed. Due to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::caeed5993daa6fe6d968e02438f91bde
https://doi.org/10.1536/jhj.45.315

Zobrazit plný text záznamu

Genetic variations of matrix metalloproteinase-1 and -3 promoter regions and their associations with susceptibility to myocardial infarction in Japanese

Autor: Koji Maemura, Tsutomu Yamazaki, Tadanori Aizawa, Takao Sugiyama, Doubun Hayashi, Yasunobu Hirata, Ryozo Nagai, Ken Ogasawara, Minoru Ohno, Akira Saito, Yasushi Imai, Hiroyuki Morita, Takefumi Nojiri

Publikováno v: International Journal of Cardiology. 92:181-186

Matrix metalloproteinases (MMPs) are involved in plaque rupture, which is the main pathological cause of myocardial infarction (MI). Recently, several genetic studies have demonstrated that MMP-1 1G/2G polymorphism and MMP-3 5A/6A polymorphism modify

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1786bc15f0f4e096b6a466e09a840a
https://doi.org/10.1016/s0167-5273(03)00100-1

Zobrazit plný text záznamu

Circulating malondialdehyde modified LDL is a biochemical risk marker for coronary artery disease

Autor: Hiroyuki Morita, Keiko Fukino, Ryozo Nagai, Y. Imai, Fumitaka Nakamura, Toru Suzuki, S Kitano, Doubun Hayashi, N Hibi, Tsutomu Yamazaki, Toshihiro Amaki, Takefumi Nojiri

Oxidatively modified low density lipoprotein (OxLDL) plays an important role in the development of atherosclerosis as its uptake by macrophages and smooth muscle cells leads to formation of foam cells which is a critical step in the evolution of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93104bdbdf03370006ab0c5c8ce4888f
https://europepmc.org/articles/PMC1768480/

Zobrazit plný text záznamu

C-reactive protein induces VCAM-1 gene expression through NF-kappaB activation in vascular endothelial cells

Autor: Daiji Kawanami, Takefumi Nojiri, Ichiro Manabe, Tomohiro Harada, Ryozo Nagai, Koji Maemura, Norihiko Takeda, Tetsuya Saito, Yasushi Imai

Publikováno v: Atherosclerosis. 185(1)

Recent studies have shown that C-reactive protein (CRP) is not just a predictor of cardiovascular events but also acts directly as a proinflammatory stimulus in vascular cells. In this report, we studied the molecular mechanisms underlying vascular c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81beea457a8412fabd7218a83041b3d3
https://pubmed.ncbi.nlm.nih.gov/16002075

Zobrazit plný text záznamu

Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1

Autor: Norihiko Takeda, Ichiro Manabe, Takefumi Nojiri, Daiji Kawanami, Tomohiro Harada, Koji Maemura, Ryozo Nagai, Yasushi Imai

Publikováno v: Circulation research. 95(2)

Endothelial PAS domain protein 1 (EPAS1) is a basic-helix-loop-helix/PAS domain transcription factor that is expressed preferentially in vascular endothelial cells. EPAS1 shares high homology with hypoxia-inducible factor-1α (HIF-1α) and is reporte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906562edc4795693f47fc063e90a914d
https://pubmed.ncbi.nlm.nih.gov/15192019

Zobrazit plný text záznamu

Development of a pioneering clinical support system utilizing information technology

Autor: Doubun, Hayashi, Yasushi, Imai, Hiroyuki, Morita, Hideo, Fujita, Koshiro, Monzen, Tomohiro, Harada, Takefumi, Nojiri, Tadashi, Yamazaki, Tsutomu, Yamazaki, Ryozo, Nagai

Publikováno v: Japanese heart journal. 45(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a15f32031ca59ac5834ca0337add0296
https://pubmed.ncbi.nlm.nih.gov/15090708

Zobrazit plný text záznamu

Genetic Analysis in a Patient With Recurrent Cardiac Myxoma and Endocrinopathy

Autor: Tsuyoshi Taketani, Takefumi Nojiri, Yoshinobu Hirata, Ryozo Nagai, Minoru Ohno, Yasushi Imai, Tomohiro Harada, Yuji Murakawa, Koji Maemura, Dobun Hayashi, Koshiro Monzen, Norihiko Takeda, Tsutomu Yamazaki, Shinichi Takamoto, Daiji Kawanami

Publikováno v: Circulation Journal. 69:994-995

A 60 year-old male was referred for treatment of a cardiac myxoma in the right atrium. He had a past history of left atrial cardiac myxoma at age 49 and pituitary microadenoma related to acromegaly at age 55. He did not have a family history of cardi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e3ac6b31350e8f075a26f47789aa50
https://doi.org/10.1253/circj.69.994

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání