Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Takefumi Kofuji"'
Autor:
Tatsuya Mishima, Kenta Komano, Marie Tabaru, Takefumi Kofuji, Ayako Saito, Yoshikazu Ugawa, Yasuo Terao
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Ultrasound is highly biopermeable and can non-invasively penetrate deep into the brain. Stimulation with patterned low-intensity ultrasound can induce sustained inhibition of neural activity in humans and animals, with potential implications for rese
Externí odkaz:
https://doaj.org/article/906b26043ccf4298a7e4e1eded24932f
Autor:
Tatsuya Mishima, Tomonori Fujiwara, Masumi Sanada, Takefumi Kofuji, Masami Kanai-Azuma, Kimio Akagawa
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90004 (2014)
Two syntaxin 1 (STX1) isoforms, HPC-1/STX1A and STX1B, are coexpressed in neurons and function as neuronal target membrane (t)-SNAREs. However, little is known about their functional differences in synaptic transmission. STX1A null mutant mice develo
Externí odkaz:
https://doaj.org/article/054ad16541714213862ed43f8bde2037
Publikováno v:
Journal of neurochemistryREFERENCESAQ8. 156(5)
De novo heterozygous mutations in the STX1B gene, encoding syntaxin 1B, cause a familial, fever-associated epilepsy syndrome. Syntaxin 1B is an essential component of the pre-synaptic neurotransmitter release machinery as a soluble N-ethylmaleimide-s
Publikováno v:
European Journal of Neuroscience. 46:2867-2874
In neuronal plasma membrane, two syntaxin isoforms, HPC-1/syntaxin 1A (STX1A) and syntaxin 1B (STX1B), are predominantly expressed as soluble N-ethylmaleimide-sensitive fusion attachment protein receptors, also known as t-SNAREs. We previously report
Publikováno v:
Behavioural Brain Research. 413:113447
Several studies have shown that oxytocin (OXT) modulates social behavior. Similarly, monoamines such as dopamine (DA) play a role in regulating social behavior. Previous studies have demonstrated that the soluble N-ethylmaleimide-sensitive fusion att
Publikováno v:
Journal of Neurochemistry. 138:117-123
HPC-1/syntaxin1A (STX1A), a neuronal soluble N-ethylmaleimide-sensitive fusion attachment protein receptor, contributes to neural function in the CNS by regulating transmitter release. Recent studies reported that STX1A is associated with human neuro
Publikováno v:
The Journal of Neuroscience. 32:381-389
The membrane protein HPC-1/syntaxin 1A is believed to play a key role in synaptic vesicle exocytosis, and it was recently suggested to be required for synaptic plasticity. Despite evidence for the function of HPC-1/syntaxin 1A in synaptic plasticity,
Publikováno v:
European Journal of Neuroscience. 32:99-107
HPC-1/syntaxin 1A (STX1A) is thought to regulate the exocytosis of synaptic vesicles in neurons. In recent human genetic studies, STX1A has been implicated in neuropsychological disorders. To examine whether STX1A gene ablation is responsible for abn
Autor:
Tatsuya Mishima, Tomoki Chiba, Takefumi Kofuji, Kimio Akagawa, Akitsugu Yamamoto, Keiji Tanaka, Tomonori Fujiwara
Publikováno v:
The Journal of Neuroscience. 26:5767-5776
The protein HPC-1/syntaxin 1A is abundantly expressed in neurons and localized in the neuronal plasma membrane. It forms a complex with SNAP-25 (25 kDa synaptosomal-associated protein) and VAMP-2 (vesicle-associated membrane protein)/synaptobrevin ca
Autor:
Tomonori Fujiwara, Tatsuya Mishima, Kimio Akagawa, Masumi Sanada, Masami Kanai-Azuma, Takefumi Kofuji
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90004 (2014)
PLoS ONE
PLoS ONE
Two syntaxin 1 (STX1) isoforms, HPC-1/STX1A and STX1B, are coexpressed in neurons and function as neuronal target membrane (t)-SNAREs. However, little is known about their functional differences in synaptic transmission. STX1A null mutant mice develo