Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Takefumi Gemba"'
Autor:
Takashi Saisu, Kazuhisa Takahashi, Takahisa Sasho, Takefumi Gemba, Koichi Nakagawa, Nobuyasu Ochiai, Momoko Arai, Ryo Murata, Seiji Ohtori, Hiroaki Tsuruoka, Kaori Sugioka
Publikováno v:
Journal of Orthopaedic Research. 28:1078-1083
The purpose of this study was to test if radial shock waves could enhance the introduction of nuclear factor-kappa B (NF-kappaB) decoy oligodeoxynucleotides, which is reported to markedly inhibit NF-kappaB activation and suppress pro-inflammatory cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9beb011f79b95060aef1d804dea9fa6
https://doi.org/10.1002/jor.21081
https://doi.org/10.1002/jor.21081
Publikováno v:
Arthritis & Rheumatism. 50:1522-1532
Objective To determine the presence of mesenchymal progenitor cells (MPCs) in human articular cartilage. Methods Primary cell cultures established from normal and osteoarthritic (OA) human knee articular cartilage were analyzed for the expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d52db57c1af73fc541ef4667916c0e
https://doi.org/10.1002/art.20269
https://doi.org/10.1002/art.20269
Autor:
Satoshi Hata, Kazushige Tanaka, Keiichi Ueda, Toshiyuki Sakaeda, Tatsurou Yagami, Takefumi Gemba, Nobuo Takasu, Yozo Hori, Kenji Asakura, Takayuki Kuroda
Publikováno v:
Molecular Pharmacology. 61:114-126
Expression of group IIA secretory phospholipase A2 (sPLA2-IIA) is documented in the cerebral cortex (CTX) after ischemia, suggesting that sPLA2-IIA is associated with neurodegeneration. However, how sPLA2-IIA is involved in the neurodegeneration rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2189ff09d5c66668b84ad5c0837610a8
https://doi.org/10.1124/mol.61.1.114
https://doi.org/10.1124/mol.61.1.114
Autor:
Yoshihiro Sakuma, Sayako Kobori, Toshihide Yamada, Seiji Ohtori, Kazuhisa Takahashi, Miyako Suzuki, Takefumi Gemba, Yasuchika Aoki, Masayuki Miyagi, Gen Inoue, Tomoaki Toyone, Takatoshi Hishiya, Yawara Eguchi, Hiroto Kamoda, Sumihisa Orita, Yasuhiro Oikawa, Gen Arai, Tetsuhiro Ishikawa
Publikováno v:
Spine. 39(15)
STUDY DESIGN Quantitative and immunohistological analysis of the efficacy of an IκB kinase-β (IKKβ) inhibitor in an injured intervertebral disc (IVD) model. OBJECTIVE To elucidate the efficacy of an IKKβ inhibitor on inflammatory cytokine levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856e22f157a6608b3d52bfb911776141
https://pubmed.ncbi.nlm.nih.gov/24825147
https://pubmed.ncbi.nlm.nih.gov/24825147
Autor:
Sumihisa Orita, Sayako Kobori, Seiji Ohtori, Tomoaki Toyone, Yawara Eguchi, Masayuki Miyagi, Gen Inoue, Tetsuhiro Ishikawa, Kazuhisa Takahashi, Yasuchika Aoki, Takefumi Gemba
Publikováno v:
The spine journal : official journal of the North American Spine Society. 13(3)
Nuclear factor-κB (NF-κB) is an essential gene transcriptional regulator of inflammatory cytokines, and it plays important roles in numerous conditions, including inflammatory and neuropathic pain, especially when discogenic pain is involved. Phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362674618bef90292aa8d06942675a93
https://pubmed.ncbi.nlm.nih.gov/23462514
https://pubmed.ncbi.nlm.nih.gov/23462514
Autor:
Kaori, Sugioka, Koichi, Nakagawa, Ryo, Murata, Nobuyasu, Ochiai, Takahisa, Sasho, Momoko, Arai, Hiroaki, Tsuruoka, Seiji, Ohtori, Takashi, Saisu, Takefumi, Gemba, Kazuhisa, Takahashi
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 28(8)
The purpose of this study was to test if radial shock waves could enhance the introduction of nuclear factor-kappa B (NF-kappaB) decoy oligodeoxynucleotides, which is reported to markedly inhibit NF-kappaB activation and suppress pro-inflammatory cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::629be16b6d5c98926ea5d404d9bac30b
https://pubmed.ncbi.nlm.nih.gov/20135689
https://pubmed.ncbi.nlm.nih.gov/20135689
Publikováno v:
Neuroscience Letters. 135:184-188
To investigate the role of glutamate release in cerebral ischemia, the amounts of amino acids (glutamate, taurine, alanine, glycine and glutamine) released in the hippocampal CA1 region of stroke-prone SHR (SHRSP), stroke-resistant SHR (SHRSR) and no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1bea2c46bd9fe17f5a148811363c6d
https://doi.org/10.1016/0304-3940(92)90432-7
https://doi.org/10.1016/0304-3940(92)90432-7
Autor:
Kazuyo Yamauchi, Kazuhisa Takahashi, Yasuchika Aoki, Takefumi Gemba, Seiji Ohtori, Yawara Eguchi, Takana Koshi, Toshinori Ito, Shunji Kishida, Tomoko Watanabe, Gen Inoue, Masashi Takaso, Masaomi Yamashita, Nobuyasu Ochiai, Sumihisa Orita, Munetaka Suzuki
Nuclear factor-kappa B (NF-kappaB) is a gene transcriptional regulator of inflammatory cytokines. We investigated the transduction efficiency of NF-kappaB decoy to dorsal root ganglion (DRG), as well as the decrease in nerve injury, mechanical allody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367dca80dcc09004c848359ff6bf07a5
https://europepmc.org/articles/PMC2899582/
https://europepmc.org/articles/PMC2899582/
Publikováno v:
The Journal of surgical research. 152(1)
One of the crucial roles of tumor extracellular matrix is to act as a barrier to drug delivery. In this study, we analyzed the relationship between the formation of tumor extracellular matrix and the efficiency of intracellular uptake of oligonucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b10e4ee81a97212c1f76406f0ef6db0
https://pubmed.ncbi.nlm.nih.gov/18533189
https://pubmed.ncbi.nlm.nih.gov/18533189
Autor:
Hideo Doya, Hideshige Moriya, Kazuhisa Takahashi, Gen Inoue, Takana Koshi, Toshinori Ito, Takefumi Gemba, Koichi Nakagawa, Nobuyasu Ochiai, Seiji Ohtori
Publikováno v:
Spine. 31(25)
Study design In vitro and in vivo study of a rat inflammatory pain model using nuclear factor-kappa B decoy. Objectives To investigate transduction efficiency of nuclear factor-kappa B decoy into dorsal root ganglion, both in vivo and in vitro, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8371b0bc2a0d693148de0a2e4e275428
https://pubmed.ncbi.nlm.nih.gov/17139220
https://pubmed.ncbi.nlm.nih.gov/17139220