Human immunodeficiency virus (HIV)-infected cells and free virus directly activate the classical complement pathway in rabbit, mouse and guinea-pig sera; activation results in virus neutralization by virolysis.

Autor: Spear, G. T., Sullivan, B. L., Takefman, D. M., Landay, A. L., Lint, T. F.

Publikováno v: Immunology; Aug91, Vol. 73 Issue 4, p377-382, 6p

Detection and characterization of porcine endogenous retrovirus in porcine plasma and porcine factor VIII.

Autor: Takefman DM; Division of Cellular and Gene Therapies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA., Wong S, Maudru T, Peden K, Wilson CA

Publikováno v: Journal of virology [J Virol] 2001 May; Vol. 75 (10), pp. 4551-7.

B lymphocytes in lymph nodes and peripheral blood are important for binding immune complexes containing HIV-1.

Autor: Jakubik JJ; Department of Immunology and Microbiology, Rush University, 1653 W. Congress Parkway, Chicago, IL. 60612, USA., Saifuddin M, Takefman DM, Spear GT

Publikováno v: Immunology [Immunology] 1999 Apr; Vol. 96 (4), pp. 612-9.

Mechanisms of resistance of HIV-1 primary isolates to complement-mediated lysis.

Autor: Takefman DM; Department of Immunology/Microbiology, Rush University, Chicago, Illinois 60612, USA., Sullivan BL, Sha BE, Spear GT

Publikováno v: Virology [Virology] 1998 Jul 05; Vol. 246 (2), pp. 370-8.

Antibodies to the HIV-1 V3 loop in serum from infected persons contribute a major proportion of immune effector functions including complement activation, antibody binding, and neutralization.

Autor: Spear GT; Department of Immunology/Microbiology, Rush Medical School, Chicago, Illinois 60612., Takefman DM, Sharpe S, Ghassemi M, Zolla-Pazner S

Publikováno v: Virology [Virology] 1994 Nov 01; Vol. 204 (2), pp. 609-15.