Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Takeaki Hiratsuka"'
Autor:
Jun-ichi Ashitani, Takuya Shimbara, Yukari Date, Takeaki Hiratsuka, Masamitsu Nakazato, Shigeru Kohno, Hiroshi Mukae, M. S. Mondal, Hiroshi Ishimoto, S. Kubo
Publikováno v:
European Respiratory Journal. 27:253-260
Human beta-defensin (hBD)-3, a 45 amino acid antimicrobial peptide, was originally isolated from human skin. hBD-3 mRNA has also been detected in the airways by RT-PCR. While hBD-3 may be involved in antimicrobial defences within the respiratory trac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20458125bf865182147aeddf1911d49a
https://doi.org/10.1183/09031936.06.00105904
https://doi.org/10.1183/09031936.06.00105904
Autor:
Shigeru Kinoshita, K Endo, Satoshi Kawasaki, Masamitsu Nakazato, Kazuto Terai, Wakako Adachi, Yoichiro Sano, Takeaki Hiratsuka, Hirotoshi Ihiboshi
Publikováno v:
Experimental Eye Research. 79:175-180
Human β-defensins (hBDs), which are mainly expressed in epithelial tissues, may contribute to infection-protective mechanisms in the ocular surface. We examined hBD1 and hBD2 expression in the ocular surface by RT-PCR and immunohistochemistry and st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a42bcf31ea9fb98bb10ad2d8cb8ef4
https://doi.org/10.1016/j.exer.2004.03.006
https://doi.org/10.1016/j.exer.2004.03.006
Publikováno v:
Journal of the Japanese Association for Infectious Diseases. 78:929-934
Eighteen patients with miliary tuberculosis (MTB) were admitted to our hospital from 1994 to 2003. The mean age of the patients was 63.9 years (range 19-92). Past history of tuberculosis was recognized in one case. Six cases suffered from another und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fd06da73d315226cf998d2d7dc472f
https://doi.org/10.11150/kansenshogakuzasshi1970.78.929
https://doi.org/10.11150/kansenshogakuzasshi1970.78.929
Autor:
Jun-ichi Ashitani, Masamitsu Nakazato, Kohno S, H Iiboshi, T Minematsu, Kazuki Nabeshima, N Chino, Toshihiko Ihi, Takeaki Hiratsuka, Hiroshi Mukae
Publikováno v:
Thorax. 58:425-430
Human beta-defensin (HBD)-1 and -2 are antimicrobial peptides present in the respiratory tract. Recent reports have indicated reduced activity of beta-defensins in cystic fibrosis, suggesting that beta-defensins may play an important role in the path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a253a19f21e5a38cf57114111351ae6
https://doi.org/10.1136/thorax.58.5.425
https://doi.org/10.1136/thorax.58.5.425
Autor:
Jun-ichi Kadota, Masamitsu Nakazato, H Iiboshi, Masatoshi Tokojima, Takeaki Hiratsuka, Shigeru Matsukura, Hiroshi Mukae, Shigeru Kohno, Jun-ichi Ashitani, Kuniko Abe
Publikováno v:
Thorax. 57:623-628
Background: Neutrophils are thought to play an important role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Human neutrophils contain antimicrobial and cytotoxic peptides in the azurophil granules which belong to a family of mammalian n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e5ae50b437297226946b21ba0a998c
https://doi.org/10.1136/thorax.57.7.623
https://doi.org/10.1136/thorax.57.7.623
Autor:
Yasuhiro Yamashita, Keiko Nishi, Takeaki Hiratsuka, Akihiko Okayama, Shota Sakaguchi, Seiichiro Hara
Publikováno v:
Kidney international. 86(3)
A 75-year-old woman with rheumatoid arthritis was admitted to our hospital because of fever and nausea. Urinary catheterization yielded a large amount of white urine (Figure 1). Non-enhanced abdominal computed tomography showed hyperdense fluid in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32be91f4987484cbabc23c46bee2394a
https://pubmed.ncbi.nlm.nih.gov/25168511
https://pubmed.ncbi.nlm.nih.gov/25168511
Autor:
Aki Hirayama, Takeaki Hiratsuka, Masamitsu Nakazato, Takahiro Mikami, Takashi Ishizu, Shinro Tachibana, Keigyou Yoh, Akio Koyama, Mitsuhiro Ino
Publikováno v:
Clinical and Experimental Nephrology. 5:163-167
Background. Defensins are antimicrobial peptides that constitute 30% to 50% of total azurophil granule proteins. Although the activation of azurophils during hemodialysis has been reported, including the release of granulocyte lactoferrin, myeloperox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3941662a2a44dcff794d665d3b5976a2
https://doi.org/10.1007/s101570170005
https://doi.org/10.1007/s101570170005
Autor:
Masamitsu Nakazato, Kenshi Kumamoto, Jun-ichi Ashitani, Hiroshi Mukae, Shigeru Matsukura, Takeaki Hiratsuka
Publikováno v:
Chest. 119:1131-1137
Study objectives To investigate the roles of human°° -defensin (HAD), human ββ-defensin (HBD)-1, and HBD-2, novel antimicrobial peptides, in patients with Mycobacterium avium-intracellulare infection (MAI). Patients The study included 25 patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d75b2fe9067901d2fcebff0d84cb076
https://doi.org/10.1378/chest.119.4.1131
https://doi.org/10.1378/chest.119.4.1131
Autor:
Akira Shimizu, Masamitsu Nakazato, Shigeru Matsukura, Toyofumi Nakanishi, Takeaki Hiratsuka, Toshio Minematsu, Kenji Kangawa, Toshihiko Ihi, Naoyoshi Chino
Publikováno v:
Nephron. 85:34-40
Human β-defensin-1 (hBD-1) is a 36-amino-acid antimicrobial peptide that functions in the host innate defense. We developed a highly sensitive radioimmunoassay for hBD-1 and identified several hBD-1 peptides in human kidney, urine, and plasma by ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e88bea251047ca5c527b63f18ff855
https://doi.org/10.1159/000045627
https://doi.org/10.1159/000045627
Autor:
Naoyoshi Chino, Shigeru Matsukura, Masamitsu Nakazato, Jun-ichi Ashitani, Toshio Minematsu, Yukari Date, Takeaki Hiratsuka
Publikováno v:
Biochemical and Biophysical Research Communications. 249:943-947
Human beta-defensin-2 (hBD-2), a novel antimicrobial peptide, was originally isolated from human skin. We found that synthetic hBD-2 has high bactericidal activity against Escherichia coli under conditions nearly the same as in human bronchial airway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e209220b75738ae6a7993e0bd3a8f800
https://doi.org/10.1006/bbrc.1998.9239
https://doi.org/10.1006/bbrc.1998.9239