Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Takayuki Shiratsuchi"'
Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance
Autor:
Joonseok Cho, Yujian Zhang, Shi-Young Park, Anna-Maria Joseph, Chul Han, Hyo-Jin Park, Srilaxmi Kalavalapalli, Sung-Kook Chun, Drake Morgan, Jae-Sung Kim, Shinichi Someya, Clayton E. Mathews, Young Jae Lee, Stephanie E. Wohlgemuth, Nishanth E. Sunny, Hui-Young Lee, Cheol Soo Choi, Takayuki Shiratsuchi, S. Paul Oh, Naohiro Terada
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Adenine nucleotide translocase (ANT) 2 promotes ADP/ATP exchange across the mitochondrial inner membrane. Choet al. show that liver specific Ant2 deletion increases uncoupled respiration and protects mice against fatty liver and obesity-induced insul
Externí odkaz:
https://doaj.org/article/27c33827aff94d8b88865b49e3ea384d
Publikováno v:
Biomolecules, Vol 2, Iss 1, Pp 23-33 (2012)
Hydrodynamic tail vein (HTV) delivery is a simple and rapid tail vein injection method of a high volume of naked plasmid DNA resulting in high levels of foreign gene expression in organs, especially the liver. Compared to other organs, HTV delivery r
Externí odkaz:
https://doaj.org/article/8aeb9857c6c64ba5bc646267f380b8c7
Publikováno v:
Antibodies, Vol 6, Iss 3, p 11 (2017)
Malaria is a mosquito-borne infectious disease caused by the parasite Plasmodium spp. Malaria continues to have a devastating impact on human health. Sporozoites are the infective forms of the parasite inside mosquito salivary glands. Circumsporozoit
Externí odkaz:
https://doaj.org/article/f9d5023a77354f6c9d9c4fc5baee24ec
Autor:
M. H. Lee, Jae-Sung Kim, Yang L, Takayuki Shiratsuchi, Young Jae Lee, Hideko Kasahara, Oh Sp, Joonseok Cho, Chae Ho Lim, Rajib Chowdhury, Seo J, Naohiro Terada
Publikováno v:
Cell Death & Differentiation. 22:1437-1450
Adenine nucleotide translocases (ANTs) transport ADP and ATP through mitochondrial inner membrane, thus playing an essential role for energy metabolism of eukaryotic cells. Mice have three ANT paralogs, Ant1 (Slc25a4), Ant2 (Slc25a5) and Ant4 (Slc25a
Autor:
S. Paul Oh, Drake Morgan, Shinichi Someya, Nishanth E. Sunny, Takayuki Shiratsuchi, Yujian Zhang, Young Jae Lee, Clayton E. Mathews, Srilaxmi Kalavalapalli, Hui-Young Lee, Joonseok Cho, Hyojin Park, Jae-Sung Kim, Sung Kook Chun, Cheol Soo Choi, Anna Maria Joseph, Chul Han, Shi Young Park, Stephanie E. Wohlgemuth, Naohiro Terada
Publikováno v:
Nature Communications
Nature Communications 8 Article number: 14477 (2017); Published: 16 February 2017; Updated: 18 August 2017 In the References section of this Article, incorrect papers are cited for references 4, 5, 7, 9, 10, 13–20 and 29–31. In addition, in the M
Publikováno v:
Biomolecules, Vol 2, Iss 1, Pp 23-33 (2012)
Biomolecules
Biomolecules; Volume 2; Issue 1; Pages: 23-33
Biomolecules
Biomolecules; Volume 2; Issue 1; Pages: 23-33
Hydrodynamic tail vein (HTV) delivery is a simple and rapid tail vein injection method of a high volume of naked plasmid DNA resulting in high levels of foreign gene expression in organs, especially the liver. Compared to other organs, HTV delivery r
Publikováno v:
Journal of Clinical Investigation. 120:3688-3701
Although adenovirus (Ad) has been regarded as an excellent vaccine vector, there are 2 major drawbacks to using this platform: (a) Ad-based vaccines induce a relatively weak humoral response against encoded transgenes, and (b) preexisting immunity to
Autor:
S. Brian Wilson, Xiangming Li, Steven A. Porcelli, Karl O.A. Yu, Mitchell Kronenberg, Vincent Lombardi, Takayuki Shiratsuchi, Jerome Kerzerho, Abinav K. Singh, Moriya Tsuji, Omid Akbari, Philippe Stock, Wen Yang, Barbara A. Sullivan, Nathan E. Hnatiuk, Amy R. Howell
Publikováno v:
The Journal of Immunology. 184:2107-2115
The prevalence of asthma continues to increase in westernized countries, and optimal treatment remains a significant therapeutic challenge. Recently, CD1d-restricted invariant NKT (iNKT) cells were found to play a critical role in the induction of ai
Autor:
Xiangming Li, Guangwu Chen, Richard W. Franck, Paolo Dellabona, Giulia Casorati, Moriya Tsuji, Takayuki Shiratsuchi
Publikováno v:
The Journal of Immunology. 183:4415-4421
C-glycoside analogues of α-galactosylceramide were shown to activate both human and mouse invariant NKT (iNKT) cells. Among these analogues, GCK152, which has an aromatic ring in the acyl chain, exhibited a stronger stimulatory activity against huma
Autor:
Takayuki Shiratsuchi, Kiichi Satoh, Tsutomu Chiba, Kentaro Sugano, Nobuyuki Hamajima, Shingo Tsuji, Hiroshi Seno, Yosuke Harada, Sunao Kawano
Publikováno v:
Journal of Gastroenterology and Hepatology. 22:729-737
Background and Aim: Helicobacter pylori (H. pylori)-induced chronic atrophic gastritis is a high-risk factor for gastric cancer. Immune responses to H. pylori are involved in gastric mucosal inflammation, and might affect clinical outcome, including