Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Takayuki Koyano"'
Autor:
Kazunori Kume, Kenji Nishikawa, Rikuto Furuyama, Takahiro Fujimoto, Takayuki Koyano, Makoto Matsuyama, Masaki Mizunuma, Dai Hirata
Publikováno v:
Open Biology, Vol 14, Iss 3 (2024)
Microtubule organization and reorganization during the cell cycle are achieved by regulation of the number, distribution and activity of microtubule-organizing centres (MTOCs). In fission yeast, the Mto1/2 complex determines the activity and distribu
Externí odkaz:
https://doaj.org/article/c7d073b0d3ee456b95080911ceb38cbf
Autor:
Masumi Namba, Tomoe Kobayashi, Mayumi Kohno, Takayuki Koyano, Takuo Hirose, Masaki Fukushima, Makoto Matsuyama
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Alport syndrome is an inherited chronic human kidney disease, characterized by glomerular basement membrane abnormalities. This disease is caused by mutations in COL4A3, COL4A4, or COL4A5 gene. The knockout mice for Col4α3, Col4α4, and Col
Externí odkaz:
https://doaj.org/article/7adc1f52cc9149c3a3047af86526ed79
Autor:
Seiya Oura, Toshiaki Hino, Takashi Satoh, Taichi Noda, Takayuki Koyano, Ayako Isotani, Makoto Matsuyama, Shizuo Akira, Kei-Ichiro Ishiguro, Masahito Ikawa
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010241 (2022)
Meiosis is a hallmark event in germ cell development that accompanies sequential events executed by numerous molecules. Therefore, characterization of these factors is one of the best strategies to clarify the mechanism of meiosis. Here, we report tr
Externí odkaz:
https://doaj.org/article/27b9a60dbc58490cba66a515fa1e2aee
Autor:
Seiya Oura, Takayuki Koyano, Chisato Kodera, Yuki Horisawa-Takada, Makoto Matsuyama, Kei-Ichiro Ishiguro, Masahito Ikawa
Publikováno v:
PLoS Genetics, Vol 17, Iss 5, p e1009412 (2021)
Meiosis is a cell division process with complex chromosome events where various molecules must work in tandem. To find meiosis-related genes, we screened evolutionarily conserved and reproductive tract-enriched genes using the CRISPR/Cas9 system and
Externí odkaz:
https://doaj.org/article/f7dec59e863341469a746fe93236290d
Autor:
Masumi Namba, Tomoe Kobayashi, Mayumi Kohno, Takayuki Koyano, Takuo Hirose, Masaki Fukushima, Makoto Matsuyama
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/bfea66473a78433a9074c2d84fb92590
Autor:
Tomoe Kobayashi, Masumi Namba, Takayuki Koyano, Masaki Fukushima, Masahiro Sato, Masato Ohtsuka, Makoto Matsuyama
Publikováno v:
BMC Biotechnology, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Recent progress in development of the CRISPR/Cas9 system has been shown to be an efficient gene-editing technology in various organisms. We recently developed a novel method called Genome-editing via Oviductal Nucleic Acids Delive
Externí odkaz:
https://doaj.org/article/ce421f7a139244faa86dd3cafea6d204
Autor:
Masato Ohtsuka, Masahiro Sato, Hiromi Miura, Shuji Takabayashi, Makoto Matsuyama, Takayuki Koyano, Naomi Arifin, Shingo Nakamura, Kenta Wada, Channabasavaiah B. Gurumurthy
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-15 (2018)
Abstract We present a robust method called improved-Genome editing via Oviductal Nucleic Acids Delivery (i-GONAD) that delivers CRISPR ribonucleoproteins to E0.7 embryos via in situ electroporation. The method generates mouse models containing single
Externí odkaz:
https://doaj.org/article/434525404bbe47ed92639ed52ed7de0a
Autor:
Mayumi Kohno, Makoto Matsuyama, Masato Ohtsuka, Tomoe Kobayashi, Masumi Namba, Takayuki Koyano
Publikováno v:
Development, Growth & Differentiation. 63:439-447
Recent advances in the CRISPR/Cas9 system have demonstrated it to be an efficient gene-editing technology for various organisms. Laboratory mice and rats are widely used as common models of human diseases; however, the current standard method to crea
Autor:
Takayuki Koyano, Kazunori Kume, Kaori Onishi, Makoto Matsuyama, Masaki Fukushima, Takashi Toda
Mutations in PKD1 or PKD2 genes lead to autosomal dominant polycystic kidney disease (ADPKD) that is the most frequent family inherited renal disorder. These genes encode polycystin-1/PC-1 and polycycstin-2/PC-2, respectively. Although the genetic ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9d50d6e2dc551ad1f2111a9cb6862bf
https://doi.org/10.1101/2022.09.20.508804
https://doi.org/10.1101/2022.09.20.508804
Autor:
Yonggang Lu, Ippei Nagamori, Hisato Kobayashi, Kanako Kojima‐Kita, Kenjiro Shirane, Hsin‐Yi Chang, Toru Nishimura, Takayuki Koyano, Zhifeng Yu, Julio M. Castañeda, Makoto Matsuyama, Satomi Kuramochi‐Miyagawa, Martin M. Matzuk, Masahito Ikawa
Publikováno v:
Journal of Reproductive Immunology. 156:103895