Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Takayuki Hisaoka"'
1
Enhancement of Rho/Rho-kinase system in regulation of vascular smooth muscle contraction in tachycardia-induced heart failure
Autor: Masateru Kohno, Masunori Matsuzaki, Shigeki Kobayashi, Michihiro Kohno, Jyutaro Yamada, Kaoru Ono, Masae Suetsugu, Tomoko Ohkusa, Masafumi Yano, Takayuki Hisaoka
Publikováno v: Cardiovascular Research. 49:319-329
Objective: The Rho/Rho-kinase system regulates Ca2+ sensitivity in vascular smooth muscle. A new drug, Y-27632, specifically inhibits Rho-kinase and hence decreases the phosphorylation of myosin light chain, thus reducing contraction. Here, we compar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e77315a4cb0393cf7f555666a1beaa
https://doi.org/10.1016/s0008-6363(00)00279-0
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2
Altered interaction of FKBP12.6 with ryanodine receptor as a cause of abnormal Ca2+ release in heart failure
Autor: Masunori Matsuzaki, Masateru Kohno, Shigeki Kobayashi, Masafumi Yano, Kaoru Ono, Michihuro Kohno, Taketo Tanigawa, Tomoko Ohkusa, Takayuki Hisaoka
Publikováno v: Cardiovascular Research. 48:323-331
Objective: Little information is available as to the Ca2+ release function of the sarcoplasmic reticulum (SR) in heart failure. We assessed whether the alteration in this function in heart failure is related to a change in the role of FK binding prot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca5ee55d6fb5f9dfb8f588d8d6620c0
https://doi.org/10.1016/s0008-6363(00)00191-7
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3
Altered Stoichiometry of FKBP12.6 Versus Ryanodine Receptor as a Cause of Abnormal Ca 2+ Leak Through Ryanodine Receptor in Heart Failure
Autor: Hiroshi Okamoto, Naoya Noguchi, Michihiro Kohno, Masateru Kohno, Takeshi Yamamoto, Masafumi Yano, Tomoko Ohkusa, Masae Suetsugu, Takayuki Hisaoka, Yuji Hisamatsu, Kaoru Ono, Masunori Matsuzaki, Shigeki Kobayashi, Shin Takasawa
Publikováno v: Circulation. 102:2131-2136
Background —In the pathogenesis of cardiac dysfunction in heart failure, a decrease in the activity of the sarcoplasmic reticulum (SR) Ca 2+ -ATPase is believed to be a major determinant. Here, we report a novel mechanism of cardiac dysfunction rev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94cca5f5ede11067e89097c4199e0e22
https://doi.org/10.1161/01.cir.102.17.2131
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4
Abnormal Ca2+ release from cardiac sarcoplasmic reticulum in tachycardia-induced heart failure
Autor: Masunori Matsuzaki, Kaoru Ono, Masafumi Yano, Yuhji Hisamatsu, Yukio Saiki, Takayuki Hisaoka, Takeshi Yamamoto, Taketo Tanigawa, Michihiro Kohno, Tomoko Ohkusa
Publikováno v: Cardiovascular Research. 44:146-155
Objective: In heart failure, little information is available as to the Ca2+ release function of sarcoplasmic reticulum (SR), which plays a major role in cardiac contractile function. Here, we assessed the rapid kinetics of drug-induced Ca2+ release f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7fc94935712c158f1576b7f1d739ceea
https://doi.org/10.1016/s0008-6363(99)00200-x
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5
Effects of balanced vasodilator, flosequinan, on aortic impedance in failing heart
Autor: Takeshi Yamamoto, Michihiro Kohno, Kaoru Ono, Backmoon Lee, Masafumi Yano, Taketo Tanigawa, Takayuki Hisaoka, Mitsuharu Konishi, Masunori Matsuzaki
Publikováno v: Journal of cardiovascular pharmacology. 32(3)
An arteriovenous vasodilator, flosequinan, has been shown to be effective for the treatment of acute heart failure. However, little is known as to its effect on aortic impedance, which is known to be a proper and precise expression of left ventricula
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a935e1611475501f87e7481ea28c03
https://pubmed.ncbi.nlm.nih.gov/9733361
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6
Polylysine-induced rapid Ca2+ release from cardiac sarcoplasmic reticulum
Autor: Takeshi Ueyama, Masunori Matsuzaki, Takayuki Hisaoka, Kaoru Ono, Masafumi Yano, Taketo Tanigawa, Takeshi Yamamoto, Tomoko Ohkusa, Michihiro Kohno
Publikováno v: Journal of cardiovascular pharmacology. 32(1)
The rapid kinetics of polylysine-induced Ca 2+ release from cardiac sarcoplasmic reticulum (SR) was assessed in combination with its effect on ryanodine binding. SR vesicles were isolated from canine cardiac SR. The time course of SR Ca 2+ release wa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf05816fee895e88273c041a7fe3c09
https://pubmed.ncbi.nlm.nih.gov/9676727
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Plný text Recenzováno Digitální knihovna AV ČR
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