Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Takayuki Ainai"'
Autor:
Kyoko Nakagawa-Goto, Hidetoshi Isawa, Tetsuji Ozawa, Masahiro Kobayashi, Takehiro Ishikawa, Masayuki Nishimura, Norihiko Kikuchi, Ritsu Suzuki, Junichi Sonehara, Yohei Saito, Takayuki Ainai, Kiyoshi Kasai, Kobayashi Makoto
Publikováno v:
Organic Process Research & Development. 24:1675-1682
An efficient route for the multikilogram synthesis of a selective β3-adrenergic receptor agonist, ritobegron ethyl hydrochloride (1), was developed by changing the coupling method of 4-hydroxynorep...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dafadea840aac24db40213f0c214e40
https://doi.org/10.1021/acs.oprd.0c00278
https://doi.org/10.1021/acs.oprd.0c00278
Autor:
Hisato Nonaka, Takayuki Ainai, Yuichi Kobayashi, Kaori Yagi, Kazushi Furukawa, Hukum P. Acharya
Publikováno v:
Tetrahedron. 62:4933-4940
CuCN-catalyzed reaction of the (1 R )-isomer of 4-cyclopentene-1,3-diol monoacetate with TBDPSO(CH 2 ) 6 MgCl produced an S N 2-type product regioselectively in high yield. Mitsunobu inversion of the product and subsequent Claisen rearrangement furni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61bed10b991998bc59349bb117d5bfe
https://doi.org/10.1016/j.tet.2006.03.001
https://doi.org/10.1016/j.tet.2006.03.001
Autor:
Hideyuki Suzuki, Kaori Yagi, Hiroyuki Ohta, Yuko Sasaki-Sekimoto, Daisuke Shibata, Yuichi Kobayashi, Ken-ichiro Takamiya, Takayuki Ainai, Nozomu Sakurai, Takeshi Obayashi, Nozomi Taki, Koichi Kobayashi, Akihiro Kikuta, Tatsuru Masuda
Publikováno v:
Plant Physiology. 139(3):1268-1283
Jasmonic acid (JA) and methyl jasmonate (MeJA), collectively known as JAs, regulate diverse physiological processes in plants, including the response to wounding. Recent reports suggest that a cyclopentenone precursor of JA, 12-oxo-phytodienoic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b124d2328a3baf5fb34169ad75c9a6dc
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100398811
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100398811
Publikováno v:
Organic Letters. 7:183-186
[Reaction: see text] Low regioselectivity of RMgBr (R = aryl, alkenyl) in the CuCN-catalyzed reaction with 4-cyclopentene-1,3-diol monoacetate is improved by addition of LiCl or MgCl2 to a similar extent as previously obtained with RMgCl (90:10). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd4c1d99a8d7e2ae194b18ceb23a234
https://doi.org/10.1021/ol047953c
https://doi.org/10.1021/ol047953c
Publikováno v:
The Journal of Organic Chemistry. 68:7825-7832
Although the supply of 12-oxo-PDA (1) and OPC-8:0 (2), the metabolites in the linolenic acid cascade leading to epi-jasmonic acid, is in demand for biological investigations, the previous syntheses of these metabolites suffer from low efficiency. Rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65c47d464fa03e8c4266fa655c93c37
https://doi.org/10.1021/jo0348571
https://doi.org/10.1021/jo0348571
Publikováno v:
Tetrahedron Letters. 44:3983-3986
Among the three types of reagents from PhMgX (X=Br, Cl) and CuCN for phenylation of 4-cyclopentene-1,3-diol monoacetate, PhMgCl/CuCN (cat.) and Ph2Cu(CN)(MgCl)2 in THF afforded the trans-1,4-isomer efficiently (82–87% yields, 91–93% regioselectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf4d01529375010695fe9d0c05a37b5
https://doi.org/10.1016/s0040-4039(03)00777-9
https://doi.org/10.1016/s0040-4039(03)00777-9
Autor:
Yuichi Kobayashi, Eisuke Takahisa, Miwa Nakano, Takayuki Ainai, Shahid B. Usmani, Modachur G. Murugesh
Publikováno v:
J. Org. Chem.. 67(No. 20):7110-7123
To construct a new strategy for synthesis of cyclopentanoids, the transition metal-catalyzed coupling reaction of cis 4-cyclopentene-1,3-diol monoacetate 1 with hard nucleophiles, R(T)-m, was investigated (eq 1 in Chart 1). Although preliminary exper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fb4256e69a7aff5a25d52c223e8ad3
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100472820
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100472820
Publikováno v:
Synlett. 2004:2582-2584
Δ 2 -OPC-8:0 (6), designed as a β-oxidation-insensitive analogue, was synthesized starting with 4-cyclopentene-1,3-diol monoacetate (5) in a stereocontrolled manner. The C(3)-C(8) moiety was first attached to the cyclopentene ring by using the Cu-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34a3db5ebd73a092e29d0015e070d0ad
https://doi.org/10.1055/s-2004-834794
https://doi.org/10.1055/s-2004-834794
Autor:
Kaori Yagi, Hisato Nonaka, Hukum P. Acharya, Kazushi Furukawa, Takayuki Ainai, Yuichi Kobayashi
Publikováno v:
ChemInform. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0621c22c3bd9977b1e1da65e9689efed
https://doi.org/10.1002/chin.200637176
https://doi.org/10.1002/chin.200637176
Autor:
Takayuki Ainai, Hukum P. Acharya, Kazushi Furukawa, Hisato Nonaka, Yuichi Kobayashi, Kaori Yagi
Publikováno v:
ChemInform. 36
CuCN-catalyzed reaction of the (1 R )-isomer of 4-cyclopentene-1,3-diol monoacetate with TBDPSO(CH 2 ) 6 MgCl produced an S N 2-type product regioselectively in high yield. Mitsunobu inversion of the product and subsequent Claisen rearrangement furni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7752803f4fb6bcc804938ff316a9e165
https://doi.org/10.1002/chin.200516198
https://doi.org/10.1002/chin.200516198