Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Takayuki Tokimasa"'
Autor:
Dennis Brown, Masuo Terashima, Johbu Itoh, Takayuki Tokimasa, Akira Saito, Yuji Fujita, Takatosi Kakuta
Publikováno v:
Tissue Engineering. 10:711-722
We investigated a portable bioartificial renal tubule device (BRTD) consisting of renal tubule cells and hollow fibers, to improve the quality of life of patients. It is necessary for a BRTD system to be compact. A compact portable BRTB requires tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2e3876c76b3d9713895a3d2e16baee
https://doi.org/10.1089/1076327041348383
https://doi.org/10.1089/1076327041348383
Autor:
Yuji Fujita, Kou Sakabe, Johbu Itoh, Akira Saito, Takayuki Tokimasa, Manabu Asano, Takatosi Kakuta
Publikováno v:
Tissue Engineering. 8:13-24
The function of current hemodialysis as an artificial kidney is insufficient because of the lack of reabsorptive function. In this study, we intend to develop a bioartificial renal tubule cell device (RTD) using tubular epithelial cells and artificia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232d803bc8c11a605841daabeef2cc86
https://doi.org/10.1089/107632702753503018
https://doi.org/10.1089/107632702753503018
Autor:
Johbu Itoh, Takatosi Kakuta, Takayuki Tokimasa, Yuji Fujita, Manabu Asano, Katuhiro Sugano, Naoko Kagiwada, Akira Saito
Publikováno v:
Journal of Artificial Organs. 3:107-111
We intend to develop a bioartificial kidney using tubular epithelial cells and artificial membranes, and to evaluate the reabsorptive function of the confluent layers. Madin-Darby canine kidney (MDCK) cells were cultured on a nucleopore polycarbonate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eaf8071b5528f614672f19b8ede45e0
https://doi.org/10.1007/bf02479975
https://doi.org/10.1007/bf02479975
Publikováno v:
Neuroscience Letters. 255:5-8
The actions of zinc on A-type potassium current (I(A)) were studied in dissociated bullfrog sympathetic neurons. Zinc (1-300 microM) caused a parallel shift in the activation and inactivation curves to a depolarizing direction, thereby enhancing I(A)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4b3d0c24200196ba5a8ac9dac23dce
https://doi.org/10.1016/s0304-3940(98)00683-1
https://doi.org/10.1016/s0304-3940(98)00683-1
Autor:
Takayuki Tokimasa, Toshihiko Nishimura
Publikováno v:
Neuroscience Letters. 236:37-40
Whole-cell/voltage-clamp recordings were made from dissociated bullfrog sympathetic neurons to examine the inhibitory actions of barium (0.01-3 mM) on a rapidly inactivating A-type potassium current (IA). The IC50 value was about 0.9 mM. Barium (1 mM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d7899519f75a5cbb4dd859ee2882a9
https://doi.org/10.1016/s0304-3940(97)00746-5
https://doi.org/10.1016/s0304-3940(97)00746-5
Autor:
R A North, Takayuki Tokimasa
Publikováno v:
The Journal of Physiology. 496:677-686
1. The effects of multivalent cations on membrane currents recorded from Xenopus oocytes were studied. 2. The hyperpolarization-activated chloride current was reversibly blocked by lanthanum; half-maximal block occurred at a concentration of 8 microM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acdbb0674acf9af63b9ab6fa36ef964b
https://doi.org/10.1113/jphysiol.1996.sp021718
https://doi.org/10.1113/jphysiol.1996.sp021718
Publikováno v:
Neuroscience Letters. 207:97-100
The mechanism underlying the over-recovery of an M-type potassium current following the washout of muscarine (20 μM) has been examined. Whole-cell recordings were made from single neurons dissociated from bullfrog sympathetic ganglia. During over-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f9a06b496b68869ddc69dc56e6c627
https://doi.org/10.1016/0304-3940(96)12495-2
https://doi.org/10.1016/0304-3940(96)12495-2
Autor:
Takashi Akasu, Mark A. Simmons, Takeshi Nakano, Masaaki Ito, Takayuki Tokimasa, Toshio Tanaka, Carla R. Schneider
Publikováno v:
British Journal of Pharmacology. 114:489-495
1. The actions of wortmannin, an inhibitor of myosin light chain kinase (MLCK), on M-type potassium current of dissociated bullfrog sympathetic neurones have been examined. 2. The amplitude of M-current was measured by whole cell recordings from cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f518f5a61591bb9d1cbff89df685cdaa
https://doi.org/10.1111/j.1476-5381.1995.tb13253.x
https://doi.org/10.1111/j.1476-5381.1995.tb13253.x
Autor:
Mitsuo Nohmi, Shao-Ying Hua, Kenji Kuba, Hiroshi Okamoto, Yasuhito Furuya, Takayuki Tokimasa, Shin Takasawa
Publikováno v:
Neuron. 12:1073-1079
Although Ca 2+ -induced Ca 2+ release (CICR) via ryanodine receptors has been found to occur in intact neurons, little is known about the physiological processes that regulate it. We studied the effects of cyclic ADP-ribose (cADPR) on CICR in culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4e531d248c45c41a987308ebdc8f9b0
https://doi.org/10.1016/0896-6273(94)90315-8
https://doi.org/10.1016/0896-6273(94)90315-8
Publikováno v:
The Journal of Physiology. 435:585-604
1. Cultured bull-frog dorsal root ganglion cells were voltage clamped in the whole-cell configuration. The cells were superfused with a nominally calcium-free Ringer solution containing tetrodotoxin (3 microM), magnesium (10 mM), cobalt (1 mM), bariu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9010d935381f958eefdf55afebdb354e
https://doi.org/10.1113/jphysiol.1991.sp018527
https://doi.org/10.1113/jphysiol.1991.sp018527