Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Takayuki, Nagasaki"'
Autor:
Kevin T. Eade, Brendan Robert E. Ansell, Sarah Giles, Regis Fallon, Sarah Harkins-Perry, Takayuki Nagasaki, Simone Tzaridis, Martina Wallace, Elizabeth A. Mills, Samaneh Farashi, Alec Johnson, Lydia Sauer, Barbara Hart, M. Elena Diaz-Rubio, Melanie Bahlo, Christian Metallo, Rando Allikmets, Marin L. Gantner, Paul S. Bernstein, Martin Friedlander
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Patient-derived induced pluripotent stem cells (iPSCs) provide a powerful tool for identifying cellular and molecular mechanisms of disease. Macular telangiectasia type 2 (MacTel) is a rare, late-onset degenerative retinal disease with an extremely h
Externí odkaz:
https://doaj.org/article/c36953378fea49618ef3b23be50c87cb
Autor:
Jin Kyun Oh, José G. Vargas Del Valle, Jose Ronaldo Lima de Carvalho, Young Joo Sun, Sarah R. Levi, Joseph Ryu, Jing Yang, Takayuki Nagasaki, Andres Emanuelli, Nailyn Rasool, Rando Allikmets, Janet R. Sparrow, Natalio J. Izquierdo, Jacque L. Duncan, Vinit B. Mahajan, Stephen H. Tsang
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-10 (2022)
Abstract Background Inherited retinal dystrophies describe a heterogeneous group of retinal diseases that lead to the irreversible degeneration of rod and cone photoreceptors and eventual blindness. Recessive loss-of-function mutations in Tubulin Tyr
Externí odkaz:
https://doaj.org/article/1e65e94f0222440682536d647ca33028
Autor:
Masahiro Kitamura, Junichi Umeo, Kyohei Kurihara, Takuji Yamato, Takayuki Nagasaki, Katsuhiko Mizota, Haruki Kogo, Shinichi Tanaka, Takashi Yoshizawa
Publikováno v:
Healthcare, Vol 11, Iss 18, p 2558 (2023)
(1) Background: This study examined the differences in changes in physical function with and without falls after daycare use among frail older adults with long-term care insurance (LTCI). (2) Methods: In this retrospective cohort study, 82 of 96 cons
Externí odkaz:
https://doaj.org/article/547c3b2756bd4934b57779c5f7a115ad
Autor:
Pei-Yin Su, Winston Lee, Jana Zernant, Stephen H. Tsang, Takayuki Nagasaki, Barbara Corneo, Rando Allikmets
Publikováno v:
Stem Cell Research, Vol 65, Iss , Pp 102973- (2022)
Pathogenic variation in the ABCA4 gene is the underlying cause of Stargardt disease, the most common inherited retinal degeneration. We established an induced pluripotent stem cell line for retinal organoid research from a patient with mild disease f
Externí odkaz:
https://doaj.org/article/3466a8aac76a4a1885d5099bcb0e51e1
Autor:
Jana Zernant, Winston Lee, Jun Wang, Kerry Goetz, Ehsan Ullah, Takayuki Nagasaki, Pei-Yin Su, Gerald A Fishman, Stephen H Tsang, Santa J Tumminia, Brian P Brooks, Robert B Hufnagel, Rui Chen, Rando Allikmets
Publikováno v:
PLoS Genetics, Vol 18, Iss 3, p e1010129 (2022)
Over 1,500 variants in the ABCA4 locus cause phenotypes ranging from severe, early-onset retinal degeneration to very late-onset maculopathies. The resulting ABCA4/Stargardt disease is the most prevalent Mendelian eye disorder, although its underlyin
Externí odkaz:
https://doaj.org/article/16ae8541b56c4895996794e432314265
Autor:
Daeryl E. Amponin, Joanna Przybek-Skrzypecka, Mariya Zyablitskaya, Anna Takaoka, Leejee H. Suh, Takayuki Nagasaki, Stephen L. Trokel, David C. Paik
Publikováno v:
BMC Ophthalmology, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Corneal infections with antibiotic-resistant microorganisms are an increasingly difficult management challenge and chemically or photochemically cross-linking the cornea for therapy presents a unique approach to managing such infe
Externí odkaz:
https://doaj.org/article/4c77a0ec0ec046a295d030193fad70c3
Publikováno v:
JCI Insight, Vol 7, Iss 2 (2022)
Background More than 1500 variants in the ATP-binding cassette, sub-family A, member 4 (ABCA4), locus underlie a heterogeneous spectrum of retinal disorders ranging from aggressive childhood-onset chorioretinopathy to milder late-onset macular diseas
Externí odkaz:
https://doaj.org/article/3cf870671925428990b2eefd46192d1a
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-24 (2019)
Abstract Background Population studies suggest that genetic factors play an important role in refractive error development; however, the precise role of genetic background and the composition of the signaling pathways underlying refractive eye develo
Externí odkaz:
https://doaj.org/article/abf4bb1182684fc789ae32dfea4ce39f
Autor:
Takashi Yoshizawa, Yusuke Kuwahara, Katsuhiko Mizota, Haruki Kogo, Shinichi Tanaka, Masahiro Kitamura, Takayuki Nagasaki
Publikováno v:
Journal of Physical Therapy Science. 35:326-329
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49d04a32f83d48865532cce3f15a10d0
https://doi.org/10.1589/jpts.35.326
https://doi.org/10.1589/jpts.35.326
Autor:
Kodai Kitagawa, Koji Matsumoto, Hayato Nodagashira, Takayuki Nagasaki, Sota Nakano, Mitsumasa Hida, Shogo Okamatsu, Chikamune Wada
Publikováno v:
International Journal of Human Movement and Sports Sciences. 10:1060-1066
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90736f975af357b72058b44a5915b2dd
https://doi.org/10.13189/saj.2022.100524
https://doi.org/10.13189/saj.2022.100524