Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Takayoshi Yoshikawa"'
Autor:
Naotake Kobayashi, Norihito Sato, Yuko Fujimura, Tsuyoshi Kihara, Katsuji Sugita, Kouji Takahashi, Katsumi Koike, Tamio Sugawara, Yukio Tada, Hiroshi Nakai, Takayoshi Yoshikawa
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 13647-13666 (2018)
Externí odkaz:
https://doaj.org/article/d165d037b7464779bcf5a8df0d389a63
Autor:
Naotake Kobayashi, Norihito Sato, Yuko Fujimura, Tsuyoshi Kihara, Katsuji Sugita, Kouji Takahashi, Katsumi Koike, Tamio Sugawara, Yukio Tada, Hiroshi Nakai, Takayoshi Yoshikawa
Publikováno v:
ACS Omega, Vol 4, Iss 4, Pp 6977-6978 (2019)
Externí odkaz:
https://doaj.org/article/fdb4daf687f24bdebc282ea868c82a00
Autor:
Norihito Sato, Tamio Sugawara, Tsuyoshi Kihara, Katsumi Koike, Takayoshi Yoshikawa, Naotake Kobayashi, Katsuji Sugita, Yukio Tada
Publikováno v:
Chemical and Pharmaceutical Bulletin. 69:314-324
We explored orally effective thyrotropin-releasing hormone (TRH) mimetics, which show high central nervous system effects in structure-activity relationship studies based on in vivo antagonistic activity on reserpine-induced hypothermia (anti-hypothe
Autor:
Naotake, Kobayashi, Norihito, Sato, Katsuji, Sugita, Tsuyoshi, Kihara, Katsumi, Koike, Tamio, Sugawara, Yukio, Tada, Takayoshi, Yoshikawa
Publikováno v:
Chemicalpharmaceutical bulletin. 69(4)
We explored orally effective thyrotropin-releasing hormone (TRH) mimetics, which show high central nervous system effects in structure-activity relationship studies based on in vivo antagonistic activity on reserpine-induced hypothermia (anti-hypothe
Autor:
Takayoshi Yoshikawa, Katsumi Koike, Yuko Fujimura, Tsuyoshi Kihara, Yukio Tada, Kouji Takahashi, Hiroshi Nakai, Katsuji Sugita, Tamio Sugawara, Norihito Sato, Naotake Kobayashi
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 13647-13666 (2018)
ACS Omega
ACS Omega
We have explored orally effective thyrotropin-releasing hormone (TRH) mimetics, showing oral bioavailability and brain penetration by structure–activity relationship (SAR) study on the basis of in vivo antagonistic activity on reserpine-induced hyp
Autor:
Yukio Tada, Norihito Sato, Takayoshi Yoshikawa, Naotake Kobayashi, Kouji Takahashi, Katsuji Sugita, Tamio Sugawara
Publikováno v:
Journal of Peptide Science. 25
We discovered the orally active thyrotropin-releasing hormone (TRH) mimetic: (4S,5S)-5-methyl-N-{(2S)-1-[(2R)-2-methylpyrrolidin-1-yl]-1-oxo-3-(1,3-thiazol-4-yl)propan-2-yl}-2-oxo-1,3-oxazolidine-4-carboxamide 1 (rovatirelin). The central nervous sys
Autor:
Naotake Kobayashi, Norihito Sato, Yuko Fujimura, Tsuyoshi Kihara, Katsuji Sugita, Kouji Takahashi, Katsumi Koike, Tamio Sugawara, Yukio Tada, Hiroshi Nakai, Takayoshi Yoshikawa
Publikováno v:
ACS Omega, Vol 4, Iss 4, Pp 6977-6978 (2019)
Autor:
Shingo Ishii, Masaki Sanekata, Yasuyuki Ariyasu, Takayoshi Yoshikawa, Yumiko Itoh, Jingoro Shimada, Takuji Komeda
Publikováno v:
Journal of Infection and Chemotherapy. 21:194-201
Peramivir is the only intravenous formulation among anti-influenza neuraminidase inhibitors currently available. Peramivir was approved for manufacturing and marketing in Japan in January 2010. In October 2010, an additional indication for pediatric
Autor:
Takuji, Komeda, Shingo, Ishii, Yumiko, Itoh, Yasuyuki, Ariyasu, Masaki, Sanekata, Takayoshi, Yoshikawa, Jingoro, Shimada
Publikováno v:
Journal of Infection and Chemotherapy. 20:689-695
Peramivir is the only intravenous formulation among anti-influenza neuraminidase inhibitors currently available. Peramivir was approved for manufacturing and marketing in Japan in January 2010. We conducted a drug use investigation of peramivir from
Publikováno v:
Drug Delivery System. 23:460-466
経肺投与は,さまざまな肺疾患に対してきわめて効率のよい薬物投与が期待されるが,製剤をリポソーム化することによって,さらに魅力的な製剤を設計することができる.リポソーム