Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Takayoshi Uchiyama"'
Publikováno v:
Journal of Clinical and Experimental Hematopathology : JCEH
Treatment outcomes of chronic lymphocytic leukemia (CLL) have improved since chemoimmunotherapy and novel drugs became available for CLL treatment; therefore, more sensitive methods to evaluate residual CLL cells in patients are required. Measurable
Publikováno v:
International Journal of Medical Sciences, Vol 9, Iss 10, Pp 901-908 (2012)
Quantification of tumor-associated mRNA extracted from blood cells/tissues containing tumor cells is used for evaluation of treatment efficacy or residual tumor cell burden in tumors including leukemia. However, this method using tumor cell-containin
Externí odkaz:
https://doaj.org/article/6fa610ebd6bf49918ede402a09705804
Autor:
Ayako Nanba, Shukuko Miyakoshi, Sadao Aoki, Keisuke Kawamoto, Takayoshi Uchiyama, Takaharu Suzuki
Publikováno v:
Journal of Clinical and Experimental Hematopathology : JCEH
Ibrutinib (IBR) covalently binds to the active site of Bruton’s tyrosine kinase (BTK) and is used for the treatment of relapsed/refractory chronic lymphocytic leukemia (CLL). Approximately 5-10% of CLL is complicated by autoimmune cytopenia (AIC),
Autor:
Miwako Narita, Shunpei Iwaya, Yoshinori Nishizawa, Masuhiro Takahashi, Minami Iwabuchi, Takayoshi Uchiyama, Jun Takizawa, Aude Bonehill, Noriyuki Kasahara, Eri Oiwa, Shigeo Hashimoto
Publikováno v:
Molecular Medicine Reports
Molecular medicine reports, vol 12, iss 2
Molecular medicine reports, vol 12, iss 2
The aim of the present study was to enhance the efficiency of leukemia immunotherapy by increasing the antigen-specific cytotoxic T lymphocyte-inducing ability of leukemia cells. The leukemic plasmacytoid dendritic cell line PMDC05 containing the HLA
Autor:
Kyogo Itoh, Tatsuo Kanda, Tsutomu Kaifu, Aichun Liu, Miwako Narita, Takayoshi Uchiyama, Minami Iwafuchi, Masahiro Minagawa, Shin-ichi Kosugi, Zhiyin Zheng, Masuhiro Takahashi, Takashi Abe
Publikováno v:
International Journal of Oncology. 46:1699-1709
Patients with advanced stage of squamous cell carcinoma of esophagus have a poor prognosis with a lethal outcome. In order to explore the feasibility and effectiveness of dendritic cell (DC)-based immunotherapy for squamous cell carcinoma of esophagu
Autor:
Masuhiro Takahashi, Yoshinori Nishizawa, Masayoshi Masuko, Miwako Narita, Shunpei Iwaya, Minami Iwabuchi, Asako Matsuyama, Eri Oiwa, Takayoshi Uchiyama
Publikováno v:
International Archives of Allergy and Immunology. 165:52-60
Background: Ustekinumab is currently used for the treatment of psoriasis with remarkable efficiency. However, worries about the development of malignancies in ustekinumab-treated patients have not been completely resolved because of the major role of
Autor:
Takayoshi Uchiyama, Masuhiro Takahashi, Hirohito Sone, Tatsuo Furukawa, Minami Iwabuchi, Miwako Narita, Aya Kojima, Naoya Satoh, Akie Yamahira, Anri Saito
Publikováno v:
International Journal of Medical Sciences
Quantification of tumor-associated mRNA extracted from blood cells/tissues containing tumor cells is used for evaluation of treatment efficacy or residual tumor cell burden in tumors including leukemia. However, this method using tumor cell-containin
Direct effect of dasatinib on proliferation and cytotoxicity of natural killer cells inin vitrostudy
Autor:
Takayoshi Uchiyama, Miwako Narita, Tatsuo Furukawa, Naoya Sato, Minami Iwabuchi, Hirohito Sone, Akie Yamahira, Masuhiro Takahashi
Publikováno v:
Hematological Oncology. 31:156-163
Lymphocytosis predominantly due to natural killer (NK) cells has been reported in nearly a half of chronic myelogenous leukemia (CML) patients who were being treated with dasatinib. Besides, dasatinib-treated patients with lymphocytosis have a better
Autor:
Shinichi Kohsaka, Hidenori Wada, Takae Hirasawa, Yumiko Ondo, Shizuyo Honda, Eri Suzuki, Yasuko Nakamura, Takayoshi Uchiyama, Shigeo Uchino, Moe Tsutsumi
Publikováno v:
Journal of Neurochemistry. 97:1203-1214
A class of scaffolding protein containing the post-synaptic density-95/Dlg/ZO-1 (PDZ) domain is thought to be involved in synaptic trafficking of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors during development. To clarif
Autor:
Akie, Yamahira, Miwako, Narita, Minami, Iwabuchi, Takayoshi, Uchiyama, Shunpei, Iwaya, Rie, Ohiwa, Yoshinori, Nishizawa, Takafumi, Suzuki, Yusaku, Yokoyama, Shigeo, Hashimoto, Jun, Takizawa, Hirohito, Sone, Masuhiro, Takahashi
Publikováno v:
Anticancer research. 34(8)
Indoleamine-2,3-dioxygenase (IDO) is a rate-limiting enzyme for tryptophan metabolism and plays an immunosuppressive role. Antigen-presenting cells, when activated, increase the expression of IDO, which results in the suppression of subsequent immune