Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Takayo Inoue"'
Autor:
Yuan Liu, Josephine Ye, Luisa Shin Ogawa, Takayo Inoue, Qin Huang, John Chu, Richard C Bates, Weiwen Ying, Andrew J Sonderfan, Patricia E Rao, Dan Zhou
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127361 (2015)
Systemic lupus erythematosus (SLE) is a complex, systemic autoimmune disease with a diverse range of immunological and clinical manifestations. The introduction of broad spectrum immunosuppressive therapies and better management of acute disease exac
Externí odkaz:
https://doaj.org/article/9d2de1569a5d4281b33a286a3638a459
Autor:
Cheryl A London, Misty D Bear, Jennifer McCleese, Kevin P Foley, Reji Paalangara, Takayo Inoue, Weiwen Ying, James Barsoum
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27018 (2011)
The novel water soluble compound STA-1474 is metabolized to ganetespib (formerly STA-9090), a potent HSP90 inhibitor previously shown to kill canine tumor cell lines in vitro and inhibit tumor growth in the setting of murine xenografts. The purpose o
Externí odkaz:
https://doaj.org/article/34d733f7e1614f0cb887dd597b2ff230
Autor:
Weiwen Ying, Dinesh Chimmanamada, Richard C. Bates, Sami Osman, Noriaki Tatsuta, Takayo Inoue, Igor Astsaturov, Vladimir Khazak, Chaohua Zhang, Suqin He, Jaime Acquaviva, Manuel Sequeira, Luisa Shin Ogawa, Jim Sang, John-Paul Jimenez, Junyi Zhang, Donald L. Smith, David A. Proia
Plasma stability assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16576181af7e8366e9045c5c59596d21
https://doi.org/10.1158/1535-7163.22506805.v1
https://doi.org/10.1158/1535-7163.22506805.v1
Autor:
Weiwen Ying, Dinesh Chimmanamada, Richard C. Bates, Sami Osman, Noriaki Tatsuta, Takayo Inoue, Igor Astsaturov, Vladimir Khazak, Chaohua Zhang, Suqin He, Jaime Acquaviva, Manuel Sequeira, Luisa Shin Ogawa, Jim Sang, John-Paul Jimenez, Junyi Zhang, Donald L. Smith, David A. Proia
The clinical benefits of chemotherapy are commonly offset by insufficient drug exposures, narrow safety margins, and/or systemic toxicities. Over recent decades, a number of conjugate-based targeting approaches designed to overcome these limitations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96f9bc9986cb6f4f2bd1cefcc5ef01b1
https://doi.org/10.1158/1535-7163.c.6538495.v1
https://doi.org/10.1158/1535-7163.c.6538495.v1
Autor:
Weiwen Ying, Dinesh Chimmanamada, Richard C. Bates, Sami Osman, Noriaki Tatsuta, Takayo Inoue, Igor Astsaturov, Vladimir Khazak, Chaohua Zhang, Suqin He, Jaime Acquaviva, Manuel Sequeira, Luisa Shin Ogawa, Jim Sang, John-Paul Jimenez, Junyi Zhang, Donald L. Smith, David A. Proia
HSP90 binding promotes the intracellular retention of HSP90 inhibitor-BODIPY probes in tumor cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014519ba899563e4f1919adfd2ea71c7
https://doi.org/10.1158/1535-7163.22506823.v1
https://doi.org/10.1158/1535-7163.22506823.v1
Autor:
Weiwen Ying, Dinesh Chimmanamada, Richard C. Bates, Sami Osman, Noriaki Tatsuta, Takayo Inoue, Igor Astsaturov, Vladimir Khazak, Chaohua Zhang, Suqin He, Jaime Acquaviva, Manuel Sequeira, Luisa Shin Ogawa, Jim Sang, John-Paul Jimenez, Junyi Zhang, Donald L. Smith, David A. Proia
Cross-species plasma stability of STA-12-8666 as a function of time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22d113ac9042df40dbd281707cfed92
https://doi.org/10.1158/1535-7163.22506802.v1
https://doi.org/10.1158/1535-7163.22506802.v1
Autor:
Weiwen Ying, Dinesh Chimmanamada, Richard C. Bates, Sami Osman, Noriaki Tatsuta, Takayo Inoue, Igor Astsaturov, Vladimir Khazak, Chaohua Zhang, Suqin He, Jaime Acquaviva, Manuel Sequeira, Luisa Shin Ogawa, Jim Sang, John-Paul Jimenez, Junyi Zhang, Donald L. Smith, David A. Proia
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56261c0c5a501d4768495f05342f25f7
https://doi.org/10.1158/1535-7163.22506808.v1
https://doi.org/10.1158/1535-7163.22506808.v1
Autor:
Keizo Koya, James Barsoum, Yumiko Wada, Luisa Shin Ogawa, Jamie Acquaviva, Shuxia Ye, Jim Sang, Noriaki Tatsuta, Takayo Inoue, Dan Zhou, Ronald K. Blackman, David A. Proia, Kevin P. Foley, Lijun Sun, Zhenjian Du, Weiwen Ying
Targeted inhibition of the molecular chaperone Hsp90 results in the simultaneous blockade of multiple oncogenic signaling pathways and has, thus, emerged as an attractive strategy for the development of novel cancer therapeutics. Ganetespib (formerly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae60d0c33c26e54380b34829efd6ddae
https://doi.org/10.1158/1535-7163.c.6536173
https://doi.org/10.1158/1535-7163.c.6536173
Autor:
Keizo Koya, James Barsoum, Yumiko Wada, Luisa Shin Ogawa, Jamie Acquaviva, Shuxia Ye, Jim Sang, Noriaki Tatsuta, Takayo Inoue, Dan Zhou, Ronald K. Blackman, David A. Proia, Kevin P. Foley, Lijun Sun, Zhenjian Du, Weiwen Ying
PDF file - 98K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717bc645823d0452677be81b15cc73d4
https://doi.org/10.1158/1535-7163.22499512.v1
https://doi.org/10.1158/1535-7163.22499512.v1
Autor:
Keizo Koya, James Barsoum, Yumiko Wada, Luisa Shin Ogawa, Jamie Acquaviva, Shuxia Ye, Jim Sang, Noriaki Tatsuta, Takayo Inoue, Dan Zhou, Ronald K. Blackman, David A. Proia, Kevin P. Foley, Lijun Sun, Zhenjian Du, Weiwen Ying
PDF file - 126K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0419c2b20bb40ada53d1f5fc54dd6de0
https://doi.org/10.1158/1535-7163.22499509
https://doi.org/10.1158/1535-7163.22499509