Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Takaya Moriyama"'
Autor:
Rina Nishii, Takanori Mizuno, Daniel Rehling, Colton Smith, Brandi L. Clark, Xujie Zhao, Scott A. Brown, Brandon Smart, Takaya Moriyama, Yuji Yamada, Tatsuo Ichinohe, Makoto Onizuka, Yoshiko Atsuta, Lei Yang, Wenjian Yang, Paul G. Thomas, Pål Stenmark, Motohiro Kato, Jun J. Yang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nucleoside analogs (NNA), such as acyclovir (ACV) and ganciclovir (GCV), are widely used as anti-virals to treat herpes virus infection. Here, Nishii et al. show that diphosphatase NUDT15 hydrolyzes ACV and GCV, therewith reducing NNA activity in vit
Externí odkaz:
https://doaj.org/article/ac367d8e92bf4e2bb684ff635f13452f
Autor:
Yoichi Tanaka, Allen Eng Juh Yeoh, Takaya Moriyama, Chi-Kong Li, Ko Kudo, Yuki Arakawa, Jassada Buaboonnam, Hui Zhang, Hsi-Che Liu, Hany Ariffin, Zhiwei Chen, Shirley K.Y. Kham, Rina Nishii, Daisuke Hasegawa, Junya Fujimura, Dai Keino, Kensuke Kondoh, Atsushi Sato, Takahiro Ueda, Masaki Yamamoto, Yuichi Taneyama, Moeko Hino, Masatoshi Takagi, Akira Ohara, Etsuro Ito, Katsuyoshi Koh, Hiroki Hori, Atsushi Manabe, Jun J. Yang, Motohiro Kato
Publikováno v:
Haematologica, Vol 106, Iss 7 (2021)
Externí odkaz:
https://doaj.org/article/1815fef0932b4b94aa0edfdfb082c81d
Autor:
Eric A. Hungate, Sapana R. Vora, Eric R. Gamazon, Takaya Moriyama, Timothy Best, Imge Hulur, Younghee Lee, Tiffany-Jane Evans, Eva Ellinghaus, Martin Stanulla, Jéremie Rudant, Laurent Orsi, Jacqueline Clavel, Elizabeth Milne, Rodney J. Scott, Ching-Hon Pui, Nancy J. Cox, Mignon L. Loh, Jun J. Yang, Andrew D. Skol, Kenan Onel
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
A risk variant located at 9p21.3 is associated with cancer risk in pediatric B-cell precursor acute lymphoblastic leukaemia. Here, the authors show that this variant affects the gene expression of the tumour suppressor gene Cdkn2b.
Externí odkaz:
https://doaj.org/article/3b8c31642c1f4f19aeefef51e4219d06
Autor:
Yiping Zhu, Dandan Yin, Yali Su, Xuyang Xia, Takaya Moriyama, Rina Nishii, Fei Liao, Shouyue Zhang, Xia Guo, Qianqian Hou, Yuan Ai, Xueyan Zhou, Shuwen Sun, Duyu Zhang, Yan Zhang, Chao Lin, Yiqi Deng, Xiaoxi Lu, Yuelan Wang, Zhigui Ma, Heyao Wang, Bo Liu, Li Yang, Wei Zhang, Jun J. Yang, Yang Shu, Ju Gao, Heng Xu
Publikováno v:
Haematologica, Vol 103, Iss 7 (2018)
Externí odkaz:
https://doaj.org/article/0b8ffb33d5264394851cf9428d3791bf
Autor:
Erick R. Scott, Yao Yang, Mariana R. Botton, Yoshinori Seki, Keito Hoshitsuki, John Harting, Primo Baybayan, Neal Cody, Paola Nicoletti, Takaya Moriyama, Shreyasee Chakraborty, Jun J. Yang, Lisa Edelmann, Eric E. Schadt, Jonas Korlach, Stuart A. Scott
Publikováno v:
Human Mutation. 43:1557-1566
To determine the phase of NUDT15 sequence variants for more comprehensive star (*) allele diplotyping, we developed a novel long-read single-molecule real-time HiFi amplicon sequencing method. A 10.5 kb NUDT15 amplicon assay was validated using refer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f406ff4b322204b3cd3c5d435891ee5
https://doi.org/10.1002/humu.24457
https://doi.org/10.1002/humu.24457
Autor:
William L. Carroll, Nikki A. Evensen, Aristotelis Tsirigos, Xiaotu Ma, Jinghui Zhang, Patrick A. Brown, Mignon L. Loh, Jun J. Yang, Kjeld Schmiegelow, David T. Teachey, Tori J. Fuller, Takaya Moriyama, Harrison L. Kilberg, Hannah Fay, Anita Qualls, Ashfiyah Chowdhury, Shella Saint Fleur-Lominy, Gunjan Sethia, Sonali Narang, Jason Saliba, Joanna Pierro
Cell line IC50 values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e42955567a62723486f8dfda7696ce2
https://doi.org/10.1158/1541-7786.22517911.v1
https://doi.org/10.1158/1541-7786.22517911.v1
Autor:
Jun J. Yang, William L. Carroll, Aleš Hnízda, Richard Heath, Youming Shao, Wentao Yang, Xujie Zhao, Julia Meyer, Jing Li, Shuguang Liu, Takaya Moriyama
Relapse remains a formidable challenge for acute lymphoblastic leukemia (ALL). Recently, recurrent mutations in NT5C2 were identified as a common genomic lesion unique in relapsed ALL and were linked to acquired thiopurine resistance. However, molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5272bb7bd6c0f8e06d3c7f4adbd03654
https://doi.org/10.1158/1535-7163.c.6539578.v1
https://doi.org/10.1158/1535-7163.c.6539578.v1
Autor:
Jun J. Yang, William L. Carroll, Aleš Hnízda, Richard Heath, Youming Shao, Wentao Yang, Xujie Zhao, Julia Meyer, Jing Li, Shuguang Liu, Takaya Moriyama
This supplementary table describes metabolite levels and statistics from metabolite experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bb0be911b08c403bcd72aa467b961a
https://doi.org/10.1158/1535-7163.22510330.v1
https://doi.org/10.1158/1535-7163.22510330.v1
Autor:
William L. Carroll, Nikki A. Evensen, Aristotelis Tsirigos, Xiaotu Ma, Jinghui Zhang, Patrick A. Brown, Mignon L. Loh, Jun J. Yang, Kjeld Schmiegelow, David T. Teachey, Tori J. Fuller, Takaya Moriyama, Harrison L. Kilberg, Hannah Fay, Anita Qualls, Ashfiyah Chowdhury, Shella Saint Fleur-Lominy, Gunjan Sethia, Sonali Narang, Jason Saliba, Joanna Pierro
Supplementary materials and methods and supplementary figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02609ec252e8f6b3c330df28d01077e1
https://doi.org/10.1158/1541-7786.22517914
https://doi.org/10.1158/1541-7786.22517914
Autor:
William L. Carroll, Nikki A. Evensen, Aristotelis Tsirigos, Xiaotu Ma, Jinghui Zhang, Patrick A. Brown, Mignon L. Loh, Jun J. Yang, Kjeld Schmiegelow, David T. Teachey, Tori J. Fuller, Takaya Moriyama, Harrison L. Kilberg, Hannah Fay, Anita Qualls, Ashfiyah Chowdhury, Shella Saint Fleur-Lominy, Gunjan Sethia, Sonali Narang, Jason Saliba, Joanna Pierro
RNAseq Gene Lists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7985eb3a5f95dead1cf23e568fefcd43
https://doi.org/10.1158/1541-7786.22517905
https://doi.org/10.1158/1541-7786.22517905