Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Takatsune, Yoshida"'
Autor:
Harshvardhan Modh, Takatsune Yoshida, Ryo Kojima, Saeed Shanehsazzadeh, Mukul Ashtikar, Masanori Kaihara, Matthias G. Wacker, Ge Fiona Gao, Tomokazu Tajiri
Publikováno v:
Journal of Controlled Release. 329:372-384
Today, tacrolimus represents a cornerstone of immunosuppressive therapy for liver and kidney transplants and remains subject of preclinical and clinical investigations, aiming at the development of long-acting depot formulations for subcutaneous inje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5072556ee62ff7eeb2a08394888dad6c
https://doi.org/10.1016/j.jconrel.2020.11.055
https://doi.org/10.1016/j.jconrel.2020.11.055
Autor:
Shin-ichiro Kimura, Masanori Kaihara, Yasunori Iwao, Yoshifumi Katakawa, Kei Motonaga, Kazuhiro Hojo, Hiromu Kondo, Takatsune Yoshida, Tomokazu Tajiri, Atsushi Kambayashi
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:467-475
The aim of this study was to establish a novel approach to in vitro dissolution evaluation using a combination of the paddle method and a dialysis membrane, both to predict the overall in vivo performance of tacrolimus microspheres and also to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::716df3c02f70a77a984fb69fe39b75e1
https://doi.org/10.1248/cpb.c18-01018
https://doi.org/10.1248/cpb.c18-01018
Autor:
Masanori, Kaihara, Kazuhiro, Hojo, Tomokazu, Tajiri, Atsushi, Kambayashi, Takatsune, Yoshida, Yoshifumi, Katakawa, Kei, Motonaga, Shin-Ichiro, Kimura, Yasunori, Iwao, Hiromu, Kondo
Publikováno v:
Chemicalpharmaceutical bulletin. 67(5)
The aim of this study was to establish a novel approach to in vitro dissolution evaluation using a combination of the paddle method and a dialysis membrane, both to predict the overall in vivo performance of tacrolimus microspheres and also to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ab524a32c8728397b03077d673cc0d0
https://pubmed.ncbi.nlm.nih.gov/31061372
https://pubmed.ncbi.nlm.nih.gov/31061372
Autor:
Ken Shimada, Akira Takagi, Umemoto Yoshiaki, Shimako Tanaka, Takatsune Yoshida, Yasuharu Kashiwagura, Shinya Uchida, Hiroyuki Kojima, Noriyuki Namiki
Publikováno v:
Journal of Drug Delivery Science and Technology. 55:101401
This study aimed to investigate the characteristics of an effective polyvinyl alcohol (PVA) for use in solid dispersion formulations (SDFs), which enable higher dissolution and bioavailability of poorly water-soluble drugs. PVAs with different degree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b410e87d34fc01d40bab6a8852e110d6
https://doi.org/10.1016/j.jddst.2019.101401
https://doi.org/10.1016/j.jddst.2019.101401
Autor:
Takatsune Yoshida, Naoto Oku, Shunsuke Watanabe, Masashi Maeda, Hiroaki Tasaki, Hiroyuki Umejima, Ryo Kojima, Yasuyuki Higashi
Publikováno v:
International Journal of Pharmaceutics. 492:20-27
The objective of this study was to elucidate the release and absorption mechanisms of tacrolimus loaded into microspheres composed of poly(lactic-co-glycolic acid) (PLGA) and/or polylactic acid (PLA). Tacrolimus-loaded microspheres were prepared by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6697fc877d58168841c3c290bdad592
https://doi.org/10.1016/j.ijpharm.2015.07.004
https://doi.org/10.1016/j.ijpharm.2015.07.004
Autor:
Akihiko Kikuchi, Takatsune Yoshida, Ippei Kurimoto, Shunsuke Watanabe, Hiroyuki Umejima, Kazuhiro Sako
Publikováno v:
Colloid and Polymer Science. 291:1191-1199
Eudragit® E/HCl salt (E–SD) displays a good antireprecipitation effect on solid dispersion formulations of poorly water-soluble drugs. To elucidate the mechanism underlying the antireprecipitation effect of E–SD, a study on supersaturation was c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e79b8f3379f0b941fd99cd772e16a052
https://doi.org/10.1007/s00396-012-2848-y
https://doi.org/10.1007/s00396-012-2848-y
Autor:
Takatsune Yoshida, Akihiko Kikuchi, Keiichi Yoshihara, Hiroyuki Umejima, Shunsuke Watanabe, Kazuhiro Sako, Ippei Kurimoto, Naoki Ito
Publikováno v:
Drug Development and Industrial Pharmacy. 39:1698-1705
This study aimed to investigate in vivo absorption of tacrolimus formulated as a solid dispersion using Eudragit E®/HCl (E-SD). E-SD is an aminoalkyl methacrylate copolymer that can be dissolved under neutral pH conditions. E-SD was used alone as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd1a5b0d4eb58c580d26842d64657155
https://doi.org/10.3109/03639045.2012.730525
https://doi.org/10.3109/03639045.2012.730525
Autor:
Kazuhiro Sako, Akihiko Kikuchi, Takatsune Yoshida, Shunsuke Watanabe, Naoki Ito, Keiichi Yoshihara, Hiroyuki Umejima, Ippei Kurimoto
Publikováno v:
International Journal of Pharmaceutics. 428:18-24
The aim of this study was to investigate the effect of Eudragit E/HCl (E-SD) on the reprecipitation of a poorly water-soluble drug, tacrolimus. To evaluate the inhibition of reprecipitation of E-SD, reprecipitation studies on tacrolimus were conducte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0400bbf08b1f02673c0f22b09635dcaa
https://doi.org/10.1016/j.ijpharm.2012.02.041
https://doi.org/10.1016/j.ijpharm.2012.02.041
Autor:
Hiroaki Tasaki, Takatsune Yoshida, Atsushi Maeda, Takahiro Uchida, Kazuhiro Sako, Masataka Katsuma
Publikováno v:
International Journal of Pharmaceutics. 365:81-88
Salting-out effects were utilized for developing a multiparticulate system balancing numbness masking and high bioavailability. A "salting-out taste-masking system" consisting of a drug core containing acetaminophen as a model drug, a salting-out lay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73198cd5c21b6d9a5b330e6334b50da5
https://doi.org/10.1016/j.ijpharm.2008.08.026
https://doi.org/10.1016/j.ijpharm.2008.08.026
Publikováno v:
Journal of Polymer Science Part A: Polymer Chemistry. 41:779-787
The synthesis and characterization of thermoresponsive hydrogels on the basis of N-isopropylacrylamide (IPAAm) copolymers crosslinked with biodegradable poly(amino acids) are described. This hydrogel was prepared with two kinds of reactive IPAAm-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd9439da79143fff3a19870d40b8c933
https://doi.org/10.1002/pola.10595
https://doi.org/10.1002/pola.10595