Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Takatoshi Karasawa"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Aminoglycoside antibiotics are used as prophylaxis, or urgent treatment, for many life-threatening bacterial infections, including tuberculosis, sepsis, respiratory infections in cystic fibrosis, complex urinary tract infections and endocarditis. Alt
Externí odkaz:
https://doaj.org/article/cb37e6794d9e4084b346881d00c97cd1
Autor:
Yuqin Yang, Fangyi Chen, Takatoshi Karasawa, Ke-Tao Ma, Bing-Cai Guan, Xiao-Rui Shi, Hongzhe Li, Peter S Steyger, Alfred L Nuttall, Zhi-Gen Jiang
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125266 (2015)
The resting membrane potential (RP) of vascular smooth muscle cells (VSMCs) is a major determinant of cytosolic calcium concentration and vascular tone. The heterogeneity of RPs and its underlying mechanism among different vascular beds remain poorly
Externí odkaz:
https://doaj.org/article/3c86c15f00b94cd391803cc4809fcaf5
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108941 (2014)
Aminoglycoside antibiotics, like gentamicin, continue to be clinically essential worldwide to treat life-threatening bacterial infections. Yet, the ototoxic and nephrotoxic side-effects of these drugs remain serious complications. A major site of gen
Externí odkaz:
https://doaj.org/article/d7ef867a04544887bd50d9d24c46de42
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66220 (2013)
Cisplatin is widely used as an antineoplastic drug, but its ototoxic and nephrotoxic side-effects, as well as the inherent or acquired resistance of some cancers to cisplatin, remain significant clinical problems. Cisplatin's selectivity in killing r
Externí odkaz:
https://doaj.org/article/5dd41c2e95994295930398c3491e778d
Autor:
Takatoshi Karasawa, Farshid Taghizadeh, Anastasiya Johnson, Peter S. Steyger, Hongzhe Li, Allan Kachelmeier, Yuan Zhang, William B. Meier, Meiyan Jiang
Publikováno v:
Science Advances
The nonselective cation channel TRPV1 is required for systemic inflammation to enhance aminoglycoside-induced hearing loss.
Aminoglycoside antibiotics are essential for treating life-threatening bacterial infections, despite the risk of lifelong
Aminoglycoside antibiotics are essential for treating life-threatening bacterial infections, despite the risk of lifelong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f3e87e41f882c749569833870300fd
http://europepmc.org/articles/PMC6636990
http://europepmc.org/articles/PMC6636990
Autor:
Adam Schwalje, Frederick J. Gallun, Juergen Theodor Fraenzer, John V. Brigande, Damir Kovačić, Stephen J. Tang, Brad N. Buran, Henry J. Adler, Nathan Barlow, Raymond L. Goldsworthy, Robert M. Raphael, Ariel Edward Hight, Barry D. Jacobson, Samuel R. Atcherson, J. Tilak Ratnanather, Marc A. Brennan, Jonathan E. Gale, Viral D. Tejani, Lina A. J. Reiss, Takatoshi Karasawa, Julia Jones Huyck, Kelsey L. Anbuhl, Sarah D. Gluck, Stacey Lim, Alexander K. Malone, Joseph Heng, Valluri R.M. Rao, Dominic V. Pisano, Patricia Stahn, Moaz Sinan, Victor Wong, Peter S. Steyger, Lisa S. Nolan, Chad Ruffin
The letter is about a community of scientists who have personally experienced the barriers imposed by hearing loss. Community represents an alternative model of distributed academic peer networking that has grown and evolved over the past 25 years. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281f13f182d58648d0129aef3d9672c8
https://www.bib.irb.hr/876960
https://www.bib.irb.hr/876960
Publikováno v:
Toxicological Sciences. 124:378-387
Aminoglycosides like gentamicin are among the most commonly used antibiotics in clinical practice and are essential for treating life-threatening tuberculosis and Gram-negative bacterial infections. However, aminoglycosides are also nephrotoxic and o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef331662ca660892aaaefb8ef9c14ad
https://doi.org/10.1093/toxsci/kfr196
https://doi.org/10.1093/toxsci/kfr196
Publikováno v:
Journal of Cell Science. 121:2871-2879
The cochlea and kidney are susceptible to aminoglycoside-induced toxicity. The non-selective cation channel TRPV4 is expressed in kidney distal tubule cells, and hair cells and the stria vascularis in the inner ear. To determine whether TRPV4 is invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73281b0c0f73d465799d8c7e0c99ccba
https://doi.org/10.1242/jcs.023705
https://doi.org/10.1242/jcs.023705
Autor:
Takatoshi Karasawa, Peter S. Steyger
Publikováno v:
Toxicology letters. 237(3)
Cisplatin is one of the most widely-used drugs to treat cancers. However, its nephrotoxic and ototoxic side-effects remain major clinical limitations. Recent studies have improved our understanding of the molecular mechanisms of cisplatin-induced nep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938e840bd71685bdac3e045dd8155338
https://pubmed.ncbi.nlm.nih.gov/26101797
https://pubmed.ncbi.nlm.nih.gov/26101797
Autor:
Yu-Qin Yang, Takatoshi Karasawa, Hongzhe Li, Zhi Gen Jiang, Ke Tao Ma, Peter S. Steyger, Alfred L. Nuttall, Xiaorui Shi, Bing Cai Guan, Fangyi Chen
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125266 (2015)
PLoS ONE
PLoS ONE
The resting membrane potential (RP) of vascular smooth muscle cells (VSMCs) is a major determinant of cytosolic calcium concentration and vascular tone. The heterogeneity of RPs and its underlying mechanism among different vascular beds remain poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad7e797599c409bcd828f11e80c812e
http://europepmc.org/articles/PMC4418701?pdf=render
http://europepmc.org/articles/PMC4418701?pdf=render