Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Takatoshi, Hikida"'
Autor:
Koki Sakurai, Makiko Morita, Yoshiatsu Aomine, Mitsunobu Matsumoto, Tetsuji Moriyama, Emiko Kasahara, Atsuo Sekiyama, Mayumi Otani, Rieko Oshima, Kate L. Loveland, Masami Yamada, Yoshihiro Yoneda, Masahiro Oka, Takatoshi Hikida, Yoichi Miyamoto
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Importin α4, which is encoded by the Kpna4 gene, is a well-characterized nuclear-cytoplasmic transport factor known to mediate transport of transcription factors including NF-κB. Here, we report that Kpna4 knock-out (KO) mice exhibit psych
Externí odkaz:
https://doaj.org/article/0e444876e7134d318d7be770966169c1
Publikováno v:
Frontiers in Human Neuroscience, Vol 18 (2024)
Accurate interoceptive processing in decision-making is essential to maintain homeostasis and overall health. Disruptions in this process have been associated with various psychiatric conditions, including depression. Recent studies have focused on n
Externí odkaz:
https://doaj.org/article/e0c7aa5d6f504c14854eea0047ad5a28
Autor:
Tomoko Tokumaru, Magdeline E. Carrasco Apolinario, Nobuyuki Shimizu, Ryohei Umeda, Koichi Honda, Kenshiro Shikano, Hitoshi Teranishi, Takatoshi Hikida, Toshikatsu Hanada, Keisuke Ohta, Yulong Li, Kazunari Murakami, Reiko Hanada
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Steatotic liver disease (SLD) is a burgeoning health problem predominantly associated with excessive alcohol consumption, which causes alcohol-related liver disease (ALD), and high caloric intake, which results in metabolic dysfunction-assoc
Externí odkaz:
https://doaj.org/article/09dc4a0c3612480e9dc4a4313df58550
Autor:
Hirotaka Nomiya, Koki Sakurai, Yoichi Miyamoto, Masahiro Oka, Yoshihiro Yoneda, Takatoshi Hikida, Masami Yamada
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract KPNA1 is a mediator of nucleocytoplasmic transport that is abundantly expressed in the mammalian brain and regulates neuronal differentiation and synaptic function. De novo mutations in Kpna1 have been identified using genome-wide associatio
Externí odkaz:
https://doaj.org/article/fcf23da3e5ad4447a479e0b6756fa4b3
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Schizophrenia is a psychiatric disorder that affects around 1% of the population in widespread populations, with severe cases leading to long-term hospitalization and necessitation of lifelong treatment. Recent studies on schizophrenia have
Externí odkaz:
https://doaj.org/article/b4e2b6cc84044cee97d984da3f1ee830
Autor:
Tatsuyuki Matsudaira, Sosuke Nakano, Yusuke Konishi, Shimpei Kawamoto, Ken Uemura, Tamae Kondo, Koki Sakurai, Takaaki Ozawa, Takatoshi Hikida, Okiru Komine, Koji Yamanaka, Yuki Fujita, Toshihide Yamashita, Tomonori Matsumoto, Eiji Hara
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Cellular senescence, a state of irreversible cell-cycle arrest caused by a variety of cellular stresses, is critically involved in age-related tissue dysfunction in various organs. However, the features of cells in the central nervous system
Externí odkaz:
https://doaj.org/article/d6b2fb2ed0004f7fb3c9b513eaae3a5e
Autor:
Tadaaki Nishioka, Suthinee Attachaipanich, Kosuke Hamaguchi, Michael Lazarus, Alban de Kerchove d’Exaerde, Tom Macpherson, Takatoshi Hikida
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Learned associations between environmental cues and the outcomes they predict (cue-outcome associations) play a major role in behavioral control, guiding not only which responses we should perform, but also which we should inhibit, in order
Externí odkaz:
https://doaj.org/article/7b3fa6a3623f4a96ab59226b28a5ce69
Autor:
Yukiko Hamasaki, Yuko Sakaue, Masahiro Matsuo, Riku Sanada, Takao Nakayama, Shugo Michikoshi, Satoko Ueba, Naoki Kurimoto, Takatoshi Hikida, Toshiya Murai
Publikováno v:
Frontiers in Child and Adolescent Psychiatry, Vol 2 (2023)
BackgroundResearch on early psychosis has begun to identify psychiatric characteristics of the prodromal period of schizophrenia; however, subclinical characteristics of children in non-psychiatric fields have not been fully investigated. In our prev
Externí odkaz:
https://doaj.org/article/92ade75cadb8480cb1cbd9a3c9b04e78
Publikováno v:
BMC Psychiatry, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Social withdrawal (hikikomori) has become an internationally recognized phenomenon, but its pathology and related factors are not yet fully known. We previously conducted a statistical case-control study on adolescent patients wit
Externí odkaz:
https://doaj.org/article/9c6726ce35214914915ace2045d6cd03
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/bffe5ec00f074fe284fe830d034add7a