Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Takato Noumi"'
Autor:
Keizo Yamashita, Takato Noumi, Hiroshi Sootome, Nobuhiro Noro, Mikiya Suda, Alastair J. King, Megumi Shibahara, Tsuyoshi Ishii
Publikováno v:
Analytical and Bioanalytical Chemistry. 390:343-348
No universal approach has been reported for specific monitoring of the catalytic activity of a wide range of kinases in cells. The present study describes an original platform for detecting the autonomous activity of serine/threonine kinases in cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0bdcca9635019ce5bab41f2df6e9bb
https://doi.org/10.1007/s00216-007-1685-1
https://doi.org/10.1007/s00216-007-1685-1
Publikováno v:
ASSAY and Drug Development Technologies. 5:523-534
The kinase signaling cascades related to mitogen- and stress-activated protein kinase-1 and -2 (MSK1 and MSK2, respectively) are attractive targets for pharmaceutical intervention, especially for neural injury. Therefore, we have developed a high thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817325e13003321a1b2bc178902afd0a
https://doi.org/10.1089/adt.2007.063
https://doi.org/10.1089/adt.2007.063
Autor:
Hiroki Inoue, Takato Noumi, Ge-Hong Sun-Wada, Keiko Hayami, Takao Yoshimizu, Hiroshi Kanazawa
Publikováno v:
Gene. 273:199-206
We cloned the genomic genes encoding the murine 16 kDa subunit (proteolipid, PL16) of vacuolar H+-ATPase (V-ATPase) and determined their nucleotide sequences. At least three independent genes were found in the murine genome. One gene consisted of thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d32b5438a82594ef95ec0d43be9503
https://doi.org/10.1016/s0378-1119(01)00590-x
https://doi.org/10.1016/s0378-1119(01)00590-x
Autor:
Shougo Ishio, Mitsuko Hayashi, Yoshinori Moriyama, Shouki Yatsushiro, Takato Noumi, Akihito Yamaguchi, Hiroshi Yamada
Publikováno v:
Neuroscience Letters. 249:143-146
It has been known that pinealocytes contain the highest level of D-aspartate among various neuroendocrine cells in the rat. Here, we report that exogenous D-aspartate strongly inhibited norepinephrine-dependent melatonin synthesis in the rat pineal g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196669bb74297e0a9412fc2498327b68
https://doi.org/10.1016/s0304-3940(98)00414-5
https://doi.org/10.1016/s0304-3940(98)00414-5
Publikováno v:
FEBS Letters. 363:264-268
The importance of negatively charged residues in transmembrane helices of many cation-coupled transporters has been widely demonstrated. Four Asp residues were located in the putative transmembrane helices of the Escherichia coli Na+/H+ antiporter, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784dd4c7502ffb72ee5afbea35913ac1
https://doi.org/10.1016/0014-5793(95)00331-3
https://doi.org/10.1016/0014-5793(95)00331-3
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1187:67-72
The mutation of serine-174 to phenylalanine that causes a defect in the Escherichia coli F 1 -ATPase β-subunit is suppressed by further mutations; Gly-149 to Ser, Ala-295 to Thr, Ala-295 to Pro, or Leu-400 to Gln (Miki, J., Fujiwara, K., Tsuda, M.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da536864a285c7cdca6dd7e85f3b33a2
https://doi.org/10.1016/0005-2728(94)90167-8
https://doi.org/10.1016/0005-2728(94)90167-8
Autor:
Masatomo Maeda, Pawinee Chaiprasert, Yoshinori Moriyama, Michiyasu Takeyama, Masayoshi Jounouchi, Masamitsu Futai, Takato Noumi
Publikováno v:
Archives of Biochemistry and Biophysics. 292:376-381
The roles of the Escherichia coli H+-ATPase (F0F1) δ subunit (177 amino acid residues) was studied by analyzing mutants. The membranes of nonsense (Gln-23 → end, Gln-29 → end, Gln-74 → end) and missense (Gly-150 → Asp) mutants had very low A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca063ac7341a1fd8d20a66ca539b031b
https://doi.org/10.1016/0003-9861(92)90005-h
https://doi.org/10.1016/0003-9861(92)90005-h
Autor:
Yoshinori Moriyama, Masamitsu Futai, Takato Noumi, Michiyasu Takeyama, Masayoshi Jounouchi, Masatomo Maeda
Publikováno v:
Archives of Biochemistry and Biophysics. 292:87-94
Escherichia coli strain KF148(SD − ) defective in translation of the uncC gene for the ϵ subunit of H + -ATPase could not support growth by oxidative phosphorylation due to lack of F 1 binding to Fo (M. Kuki, T. Noumi, M. Maeda, A. Amemura, and M.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eb075c24ea54bc1042dab74f5f96a93
https://doi.org/10.1016/0003-9861(92)90054-z
https://doi.org/10.1016/0003-9861(92)90054-z
Publikováno v:
Proceedings of the National Academy of Sciences. 88:1938-1942
Yeast mutants in which genes encoding subunits of the vacuolar H(+)-ATPase were interrupted were assayed for their vacuolar ATPase and proton-uptake activities. The vacuoles from the mutants lacking subunits A (72 kDa), B (57 kDa), or c (proteolipid,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39691d5bb923cd5c7377e8b8dc4d5303
https://doi.org/10.1073/pnas.88.5.1938
https://doi.org/10.1073/pnas.88.5.1938
Autor:
Tsuyoshi, Ish, Hiroshi, Sootome, Alastair J, King, Mikiya, Suda, Nobuhiro, Noro, Keizo, Yamashita, Takato, Noumi, Tsuyoshi, Ishii
Publikováno v:
Journal of biomolecular screening. 12(6)
Checkpoint kinase 1 (Chk1), a serine/threonine kinase, plays an important role in DNA damage checkpoint control and is an attractive target for cancer treatment. To develop a Chk1-specific cell-based assay, stable clones were established in which Chk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d0506add3905503ae5139bc6312df3
https://pubmed.ncbi.nlm.nih.gov/17517898
https://pubmed.ncbi.nlm.nih.gov/17517898