Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Takato Hara"'
Autor:
Takato Hara1 takato.hara@phar.toho-u.ac.jp, Shogo Matsuura1, Keita Aikawa1, Misaki Shirai1, Mai Yoshida1, Toshiyuki Kaji2, Chika Yamamoto1 yamamoto@phar.toho-u.ac.jp
Publikováno v:
Journal of Toxicological Sciences. 2023, Vol. 48 Issue 8, p457-467. 11p.
Publikováno v:
Fundamental Toxicological Sciences; 2024, Vol. 11 Issue 4, p205-213, 9p
Autor:
Takato Hara, Tomoko Konishi, Shuji Yasuike, Yasuyuki Fujiwara, Chika Yamamoto, Toshiyuki Kaji
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3656 (2023)
Vascular endothelial cells synthesize and secrete perlecan, a large heparan sulfate proteoglycan that increases the anticoagulant activity of vascular endothelium by inducing antithrombin III and intensifying fibroblast growth factor (FGF)-2 activity
Externí odkaz:
https://doaj.org/article/eee649ae66db4c23b54ce4de8cb98583
Publikováno v:
Biochemistry and Biophysics Reports, Vol 26, Iss , Pp 101001- (2021)
Syndecan-1 and syndecan-4 are members of the syndecan family of transmembrane heparan sulfate proteoglycans. Vascular endothelial cells synthesize both species of proteoglycans and use them to regulate the blood coagulation-fibrinolytic system and th
Externí odkaz:
https://doaj.org/article/69f229b2f7404bc0b80603b6be9adbaa
Autor:
Musubu Takahashi, Tomoya Fujie, Tsuyoshi Nakano, Takato Hara, Yasuhiro Shinkai, Ryoko Takasawa, Yasushi Hara, Yoshito Kumagai, Chika Yamamoto, Toshiyuki Kaji
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11762 (2021)
Transforming growth factor-β1 (TGF-β1) occurs at high levels at damage sites of vascular endothelial cell layers and regulates the functions of vascular endothelial cells. Reactive sulfur species (RSS), such as cysteine persulfide, glutathione pers
Externí odkaz:
https://doaj.org/article/71c25b141ccd4f8b81de3f5e659cdf80
Autor:
Takato Hara, Takahiro Okazaki, Tamayo Hashiya, Kyohei Nozawa, Shuji Yasuike, Jyoji Kurita, Chika Yamamoto, Noriaki Hamada, Toshiyuki Kaji
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10520 (2021)
Among organic–inorganic hybrid molecules consisting of organic structure(s) and metal(s), only few studies are available on the cytotoxicity of nucleophilic molecules. In the present study, we investigated the cytotoxicity of a nucleophilic organot
Externí odkaz:
https://doaj.org/article/4b0664c8fbec4ad697c5d9e799d8db27
Autor:
Takato Hara1, Miki Sakuma1, Tomoya Fujie1, Toshiyuki Kaji2, Chika Yamamoto1 yamamoto@phar.toho-u.ac.jp
Publikováno v:
Journal of Toxicological Sciences. 2021, Vol. 46 Issue 5, p249-253. 5p.
Autor:
Tomoya Fujie, Akane Takahashi, Musubu Takahashi, Takato Hara, Asuka Soyama, Kosho Makino, Hideyo Takahashi, Chika Yamamoto, Yoshito Kumagai, Hiroshi Naka, Toshiyuki Kaji
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6053 (2020)
As toxic substances can enter the circulating blood and cross endothelial monolayers to reach parenchymal cells in organs, vascular endothelial cells are an important target compartment for such substances. Reactive sulfur species protect cells again
Externí odkaz:
https://doaj.org/article/2e462a8c7f7942a3bc046e3767d28e56
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 10, p 3698 (2020)
Syndecan-4 is a member of the syndecan family of transmembrane heparan sulfate proteoglycans, and is involved in cell protection, proliferation, and the blood coagulation-fibrinolytic system in vascular endothelial cells. Heparan sulfate chains enabl
Externí odkaz:
https://doaj.org/article/66255ef2b5ed4b44a21833cf69564f3a
Publikováno v:
Journal of Toxicological Sciences. 2020, Vol. 45 Issue 12, p795-800. 6p.