Anti-gametocyte antigen humoral immunity and gametocytemia during treatment of uncomplicated falciparum malaria: a multi-national study

Autor: O'Flaherty, K, Chan, J-A, Cutts, JC, Zaloumis, SG, Ashley, EA, Phyo, AP, Drew, DR, Dondorp, AM, Day, NP, Dhorda, M, Fairhurst, RM, Lim, P, Amaratunga, C, Pukrittayakamee, S, Hien, TT, Htut, Y, Mayxay, M, Faiz, MA, Mokuolu, OA, Onyamboko, MA, Fanello, C, Takashima, E, Tsuboi, T, Theisen, M, Nosten, F, Beeson, JG, Simpson, JA, White, NJ, Fowkes, FJI

Publikováno v: O'Flaherty, K, Chan, J-A, Cutts, J C, Zaloumis, S G, Ashley, E A, Phyo, A P, Drew, D R, Dondorp, A M, Day, N P, Dhorda, M, Fairhurst, R M, Lim, P, Amaratunga, C, Pukrittayakamee, S, Hien, T T, Htut, Y, Mayxay, M, Faiz, M A, Mokuolu, O A, Onyamboko, M A, Fanello, C, Takashima, E, Tsuboi, T, Theisen, M, Nosten, F, Beeson, J G, Simpson, J A, White, N J & Fowkes, F J I 2022, ' Anti-gametocyte antigen humoral immunity and gametocytemia during treatment of uncomplicated falciparum malaria : A multi-national study ', Frontiers in Cellular and Infection Microbiology, vol. 12, pp. 804470 . https://doi.org/10.3389/fcimb.2022.804470
Frontiers in cellular and infection microbiology, 12:804470. Frontiers Media S.A.

IntroductionUnderstanding the human immune response to Plasmodium falciparum gametocytes and its association with gametocytemia is essential for understanding the transmission of malaria as well as progressing transmission blocking vaccine candidates

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Host immunity and the assessment of emerging artemisinin resistance in a multinational cohort

Autor: Ataide, R, Ashley, EA, Powell, R, Chan, J-A, Malloy, M, O'Flaherty, K, Takashima, E, Langer, C, Tsuboi, T, Dondorp, AM, Day, NP, Dhorda, M, Fairhurst, RM, Lim, P, Amaratunga, C, Pukrittayakamee, S, Hien, TT, Htut, Y, Mayxay, M, Faiz, MA, Beeson, JG, Nosten, F, Simpson, JA, White, N, Fowkes, FJI

38 Artemisinin-resistant falciparum malaria, defined by a slow-clearance phenotype and the presence of kelch13 mutants, has emerged in the Greater Mekong Subregion. Naturally-acquired immunity to malaria clears parasites independently of antimalarial

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