Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Takashi YAZAWA"'
Autor:
Takashi Yazawa, Yugo Watanabe, Yuko Yokohama, Yoshitaka Imamichi, Kazuya Hasegawa, Ke-ichi Nakajima, Takeshi Kitano, Takanori Ida, Takahiro Sato, Mohammad Sayful Islam, Akihiro Umezawa, Satoru Takahashi, Yasuhito Kato, Sharmin Jahan, Jun-ichi Kawabe
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
3β-Hydroxysteroid dehydrogenases (3β-HSDs) catalyze the oxidative conversion of delta (5)-ene-3-beta-hydroxy steroids and ketosteroids. Human 3β-HSD type 2 (HSD3B2) is predominantly expressed in gonadal and adrenal steroidogenic cells for producin
Externí odkaz:
https://doaj.org/article/8b8186365c784724afed80dc9e31ad03
Autor:
Yumiko Miyazaki, Makoto Orisaka, Yuko Fujita, Tetsuya Mizutani, Takashi Yazawa, Yoshio Yoshida
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundSex steroid hormones, primarily synthesized by gonadal somatic cells, are pivotal for sexual development and reproduction. Mice studies have shown that two transcription factors, steroidogenic factor 1 (SF-1) and Wilms’ tumor 1 (WT1), are
Externí odkaz:
https://doaj.org/article/d88fc1933be44487a5040c470c1a0a0e
Autor:
Takanori Ida, Hatsumi Tominaga, Eri Iwamoto, Akito Kurogi, Ayaka Okura, Kengo Shimada, Johji Kato, Atsutoshi Kuwano, Hirotaka Ode, Sayaka Nagata, Kazuo Kitamura, Takashi Yazawa, Miho Sato-Hashimoto, Masahiro Yasuda, Mikiya Miyazato, Yuki Shiimura, Takahiro Sato, Masayasu Kojima
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Ghrelin is a peptide hormone with various important physiological functions. The unique feature of ghrelin is its serine 3 acyl-modification, which is essential for ghrelin activity. The major form of ghrelin is modified with n-octanoic acid (C8:0) b
Externí odkaz:
https://doaj.org/article/d85534026b95427a8a6a7170dbadf579
Autor:
Takamitsu Tatsukawa, Kohei Kano, Kei-ichi Nakajima, Takashi Yazawa, Ryoji Eguchi, Maki Kabara, Kiwamu Horiuchi, Taiki Hayasaka, Risa Matsuo, Naoyuki Hasebe, Nobuyoshi Azuma, Jun-ichi Kawabe
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Background Skeletal muscle comprises almost 40% of the human body and is essential for movement, structural support and metabolic homeostasis. Size of multinuclear skeletal muscle is stably maintained under steady conditions with the sporadi
Externí odkaz:
https://doaj.org/article/1c87004fecaf4f1586d46cc9af202d0d
Autor:
Sangwoo Kim, Takashi Yazawa, Akari Koide, Erina Yoneda, Risa Aoki, Tatsuki Okazaki, Kisaki Tomita, Hiroyuki Watanabe, Yoshikage Muroi, Masafumi Testuka, Yuki Muranishi
Publikováno v:
Biology, Vol 13, Iss 5, p 284 (2024)
Adipose tissue plays an important role in regulating body temperature and metabolism, with white adipocytes serving as storage units for energy. Recent research focused on the browning of white adipocytes (beige adipocytes), causing thermogenesis and
Externí odkaz:
https://doaj.org/article/cea15c509f2a48a5874352d1ec058d0e
Autor:
Takashi Yazawa, Yoshitaka Imamichi, Takeshi Kitano, Mohammad Sayful Islam, Md. Rafiqul Islam Khan, Satoru Takahashi, Toshio Sekiguchi, Nobuo Suzuki, Akihiro Umezawa, Junsuke Uwada
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract It was reported that nicotinic acetylcholine receptor (nAChR)-mediated signaling pathways affect the proliferation and differentiation of pluripotent stem cells. However, detail expression profiles of nAChR genes were unrevealed in these cel
Externí odkaz:
https://doaj.org/article/24fbf7d6a3194d21bd165200233b6b35
Autor:
Ryuichiro Sato, Masaya Oikawa, Tetsuya Kakita, Takaho Okada, Tomoya Abe, Takashi Yazawa, Haruyuki Tsuchiya, Naoya Akazawa, Shingo Yoshimachi, Haruka Okano, Kei Ito, Takashi Tsuchiya
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 6, Iss 1, Pp 40-51 (2022)
Objectives: Understanding the relationship between sarcopenia and malignancy is increasingly important since they inevitably affect the aging population. We investigated the clinical significance of sarcopenia in nonmetastatic obstructive colorectal
Externí odkaz:
https://doaj.org/article/499496b9c22a4ca09718504659e991a4
Autor:
Ryuichiro Sato, Masaya Oikawa, Tetsuya Kakita, Takaho Okada, Tomoya Abe, Takashi Yazawa, Haruyuki Tsuchiya, Naoya Akazawa, Shingo Yoshimachi, Haruka Okano, Kei Ito, Takashi Tsuchiya
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 5, Iss 4, Pp 366-375 (2021)
Objectives: It has been increasingly recognized that the progression of cancer is dependent not only on the tumor characteristics but also on the nutritious and inflammatory condition of the host. We investigated the relationship between the globulin
Externí odkaz:
https://doaj.org/article/9813f20f6c754f22844ceebe421e46aa
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Medaka (Oryzias latipes) is a teleost fish with an XX/XY sex determination system. Sex reversal from female-to-male (masculinization of XX fish) can be induced through cortisol elevation from exposure to environmental stress such as high temperature
Externí odkaz:
https://doaj.org/article/40bbd8ad309b408681d3055c5159007e
Autor:
Nobuo Suzuki, Masato Honda, Masayuki Sato, Shuhei Yoshitake, Kimi Kawabe, Yoshiaki Tabuchi, Toshiki Omote, Toshio Sekiguchi, Yukihiro Furusawa, Akira Toriba, Ning Tang, Yohei Shimasaki, Edward G. Nagato, Lulu Zhang, Ajai K. Srivastav, Thumronk Amornsakun, Yoichiro Kitani, Hajime Matsubara, Takashi Yazawa, Jun Hirayama, Atsuhiko Hattori, Yuji Oshima, Kazuichi Hayakawa
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 234, Iss , Pp 113401- (2022)
To study the toxicity of 3-hydroxybenzo[c]phenanthrene (3-OHBcP), a metabolite of benzo[c]phenanthrene (BcP), first we compared it with its parent compound, BcP, using an in ovo-nanoinjection method in Japanese medaka. Second, we examined the influen
Externí odkaz:
https://doaj.org/article/764474b9c70f4d4c9b905969cf4fca06