Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Takashi Ushimaru"'
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Microautophagy, which degrades cargos by direct lysosomal/vacuolar engulfment of cytoplasmic cargos, is promoted after nutrient starvation and the inactivation of target of rapamycin complex 1 (TORC1) protein kinase. In budding ye
Externí odkaz:
https://doaj.org/article/8ec4e64dc78a4bf4acb7aeb7edb86c8a
Autor:
Chihiro Yamada, Aya Morooka, Seira Miyazaki, Masayoshi Nagai, Satoru Mase, Kenji Iemura, Most Naoshia Tasnin, Tsuneyuki Takuma, Shotaro Nakamura, Shamsul Morshed, Naoki Koike, Md. Golam Mostofa, Muhammad Arifur Rahman, Tasnuva Sharmin, Haruko Katsuta, Kotaro Ohara, Kozo Tanaka, Takashi Ushimaru
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103675- (2022)
Summary: Unsatisfied kinetochore-microtubule attachment activates the spindle assembly checkpoint to inhibit the metaphase-anaphase transition. However, some cells eventually override mitotic arrest by mitotic slippage. Here, we show that inactivatio
Externí odkaz:
https://doaj.org/article/1022385d83204cfdbe69989bb4c99062
Autor:
Tsuneyuki Takuma, Takashi Ushimaru
Publikováno v:
Biochemical and Biophysical Research Communications. 614:161-168
Vacuoles and lysosomes are organelles involved in the degradation of cytoplasmic proteins and organelles. Vacuolar morphology is dynamically regulated by fission and fusion in budding yeast. Vacuolar fusion is elicited in nutrient-depleted conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d631bd678bea9d8fa013f5f367c529f
https://doi.org/10.1016/j.bbrc.2022.05.021
https://doi.org/10.1016/j.bbrc.2022.05.021
Autor:
Md. Golam Mostofa, Shamsul Morshed, Ritsu Shibata, Yuri Takeichi, Muhammad Arifur Rahman, Shun Hosoyamada, Takehiko Kobayashi, Takashi Ushimaru
Publikováno v:
Cell Reports, Vol 28, Iss 13, Pp 3423-3434.e2 (2019)
Summary: Nutrient starvation and inactivation of target of rapamycin complex 1 (TORC1) protein kinase induce nucleophagy preferentially degrading only nucleolar components in budding yeast. Nucleolar proteins are relocated to sites proximal to the nu
Externí odkaz:
https://doaj.org/article/337d05b719de4920b647c5e0498b3e49
Publikováno v:
Biochemical and Biophysical Research Communications. 552:1-8
The degradation of nucleolar proteins - nucleophagy - is elicited by nutrient starvation or the inactivation of target of rapamycin complex 1 (TORC1) protein kinase in budding yeast. Prior to nucleophagy, nucleolar proteins migrate to the nucleus-vac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b6660aae692299fb86d38af4e3c603
https://doi.org/10.1016/j.bbrc.2021.03.033
https://doi.org/10.1016/j.bbrc.2021.03.033
Publikováno v:
Biochemical and Biophysical Research Communications. 550:158-165
Chromosomes have their own territories and dynamically translocate in response to internal and external cues. However, whether and how territories and the relocation of chromosomes are controlled by other intracellular organelles remains unknown. Upo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e21c8cee19a693d4e18eb67d5fcf8fe
https://doi.org/10.1016/j.bbrc.2021.02.141
https://doi.org/10.1016/j.bbrc.2021.02.141
Publikováno v:
Biochemical and biophysical research communications. 611
When asynchronously growing cells suffer from nutrient depletion and inactivation of target of rapamycin complex 1 (TORC1) protein kinase, the rDNA (rRNA gene) region is condensed in budding yeast Saccharomyces cerevisiae, which is executed by conden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7251b3e174cd5325a5522f0cf8f3fa36
https://pubmed.ncbi.nlm.nih.gov/35477092
https://pubmed.ncbi.nlm.nih.gov/35477092
Autor:
Akter Mst Yeasmin, Talukdar Muhammad Waliullah, Akihiro Kondo, Atsuki Kaneko, Naoki Koike, Takashi Ushimaru
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0166636 (2016)
Target of rapamycin complex 1 (TORC1) phosphorylates autophagy-related Atg13 and represses autophagy under nutrient-rich conditions. However, when TORC1 becomes inactive upon nutrient depletion or treatment with the TORC1 inhibitor rapamycin, Atg13 d
Externí odkaz:
https://doaj.org/article/41c5d2f9827c48398286ef82d39f5014
Autor:
Haruko Katsuta, Kisara Ito, Tasnuva Sharmin, Most Naoshia Tasnin, Takashi Ushimaru, Tsuneyuki Takuma
Publikováno v:
Journal of molecular biology. 434(2)
Phosphatidylinositol 3-phosphate (PI3P), a scaffold of membrane-associated proteins required for diverse cellular events, is produced by Vps34-containing phosphatidylinositol 3-kinase (PI3K). PI3K complex I (PI3KCI)-generated PI3P is required for mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6016cf1f25e4f28c67686fe920dc11
https://pubmed.ncbi.nlm.nih.gov/34798133
https://pubmed.ncbi.nlm.nih.gov/34798133
Autor:
Golam Mostofa, Kisara Ito, Takashi Ushimaru, Muhammad Arifur Rahman, Ritsu Shibata, Shamsul Morshed, Takahiro Mochida
Publikováno v:
Biochemical and Biophysical Research Communications. 519:302-308
Nucleolar proteins such as Nop1/fibrillarin are degraded by nucleophagy in nutrient-starved conditions. However, whether and how excess nucleolar proteins are removed in normal conditions is unknown. Here we show that overexpressed nucleolar protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cdb2c624e15ab52031e9e0bc6c9163d
https://doi.org/10.1016/j.bbrc.2019.09.002
https://doi.org/10.1016/j.bbrc.2019.09.002