Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Takashi Uchimura"'
1
Ka-band cryogenic low-noise receiver of the Misasa 54 m antenna for deep-space communications and radio astronomy
Autor: Masato Tsuboi, Yutaka Hasegawa, Go Tabuchi, Yasuhiro Murata, Koji Yuchi, Tomoaki Toda, Takashi Uchimura, Kimihiro Kimura, Takashi Kasuga
Publikováno v: Publications of the Astronomical Society of Japan.
We built a Ka-band dual-circular-polarization low-noise receiver for the Misasa 54 m parabola antenna in Misasa, Japan. The antenna is designed to be combined with a transmitter and receiver system at the X band (around 8 GHz) and simultaneously with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d3d2d0a8b2bdcc43058cb4cac152ec1
https://doi.org/10.1093/pasj/psad020
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2
Bmp2andBmp4genetically interact to support multiple aspects of mouse development including functional heart development
Autor: Yoshihiro Komatsu, Kelly L. McCann, Yuji Mishina, Takashi Uchimura, Momo Tanaka
Publikováno v: genesis. 47:374-384
Bone morphogenetic proteins (BMPs) have multiple roles during embryogenesis. Current data indicate that the dosage of BMPs is tightly regulated for normal development in mice. Since Bmp2 or Bmp4 homozygous mutant mice show early embryonic lethality,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ed767c4a966acc26a37458892a319a
https://doi.org/10.1002/dvg.20511
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3
Dissecting the Role of Rho-mediated Signaling in Contractile Ring Formation
Autor: Keiju Kamijo, Jae Seon Lee, Hiroshi Hosoya, Takashi Uchimura, Toru Miki, Mitsuhiro Abe, Naoya Ohara
Publikováno v: Molecular Biology of the Cell. 17:43-55
In anaphase, microtubules provide a specification signal for positioning of the contractile ring. However, the nature of the signal remains unknown. The small GTPase Rho is a potent regulator of cytokinesis, but the involvement of Rho in contractile
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1fbfa1ddb533af5630b541bb7c8048
https://doi.org/10.1091/mbc.e05-06-0569
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4
Simultaneous analytical method for the determination of TCH346 and its four metabolites in human plasma by liquid chromatography/tandem mass spectrometry
Autor: Tomoyoshi Naganuma, Yusuke Nagae, Hisanori Hara, Naoki Masuda, Naotsugu Akashi, Tetsushi Aizawa, Takashi Uchimura
Publikováno v: Rapid Communications in Mass Spectrometry. 18:377-384
TCH346 (dibenzo[b,f]oxepin-10-ylmethyl-prop-2-ynylamine) is a novel propargylamine compound under investigation as a putative agent in the treatment of chronic neurodegenerative illnesses. To support clinical studies an analytical method was develope
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d62c23396961dc0f774865e821e6e5
https://doi.org/10.1002/rcm.1349
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5
Phosphorylation of myosin II regulatory light chain is necessary for migration of HeLa cells but not for localization of myosin II at the leading edge
Autor: Takashi Uchimura, Katsumi Fumoto, Hiroshi Hosoya, Kozue Ueda, Takahiro Iwasaki
Publikováno v: Biochemical Journal. 370:551-556
To investigate the role of phosphorylated myosin II regulatory light chain (MRLC) in living cell migration, these mutant MRLCs were engineered and introduced into HeLa cells. The mutant MRLCs include an unphosphorylatable form, in which both Thr-18 a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c554aca8de0b07bd69f3471d38877a
https://doi.org/10.1042/bj20021559
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6
A Monoclonal Antibody Raised Against an 86-kD Subunit of Human DNA Helicase II
Autor: Takahiro Iwasaki, Maki Murata-Hori, Tsuneyoshi Horigome, Saburo Omata, Hiroshi Hosoya, Natsumi Hosoya, Takashi Uchimura
Publikováno v: Zoological Science. 17:1255-1259
Here we produced a monoclonal antibody (termed as mH2) which specifically recognized an 86-kD subunit of Human DNA helicase II (p86) in HeLa cells. Immunohistochemical analysis of p86 throughout the cell cycle showed that its localization was changed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4cd05a558e0f153fb9e0758443b15892
https://doi.org/10.2108/zsj.17.1255
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7
Effect of Non-Insulin Dependent Diabetes on Cyclosporin A Disposition in Goto-Kakizaki (GK) Rats
Autor: Masaki Ogata, Yukisumi Iizuka, Ryo Murata, Takayoshi Toyota, Noboru Hikichi, Takashi Uchimura, Susumu Suzuki
Publikováno v: Biological and Pharmaceutical Bulletin. 20:1026-1029
We previously reported that the pharmacokinetics of cyclosporin A (CyA), particularly absorption, were altered in diabetic rats treated with streptozotocin. In the present study, the effect of diabetes on pharmacokinetics of CyA after intravenous and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb27aba4f71719c185d367920d801aa5
https://doi.org/10.1248/bpb.20.1026
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8
Diphosphorylated but not monophosphorylated myosin II regulatory light chain localizes to the midzone without its heavy chain during cytokinesis
Autor: Hiroshi Hosoya, Kozue Hamao, Rieko Isoda, Mutsumi Sugiyama, Tomo Kondo, Takashi Uchimura
Publikováno v: Biochemical and biophysical research communications. 417(2)
Myosin II is activated by the monophosphorylation of its regulatory light chain (MRLC) at Ser19 (1P-MRLC). Its ATPase activity is further enhanced by MRLC diphosphorylation at Thr18/Ser19 (2P-MRLC). As these phosphorylated MRLCs are colocalized with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea78d3d0a031c09f8be4c5c09e0eb07d
https://pubmed.ncbi.nlm.nih.gov/22166199
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