Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Takashi Tsuyama"'
Autor:
Kenju Matsusaka, Yutaro Azuma, Yuki Kaga, Saeka Uchida, Yuri Takebayashi, Takashi Tsuyama, Shusuke Tada
Publikováno v:
Biochemistry and Biophysics Reports, Vol 29, Iss , Pp 101222- (2022)
Calreticulin (CRT), a chaperone typically located in the endoplasmic reticulum (ER), is known to translocate to the cell surface in response to anticancer drugs. Cell surface CRT (ecto-CRT) on apoptotic or pre-apoptotic cells serves as an “eat me
Externí odkaz:
https://doaj.org/article/1d2ff0a109844e2db8800299238b5cb7
Autor:
Yutaro Azuma, Shiori Hamanaka, Kana Kusuzaki, Akira Ogawa, Shusuke Tada, Kumiko Fujita, Ryosuke Sasaki, Takashi Tsuyama, Yuki Sotoyama
Publikováno v:
Gene. 787
RecQ4, a member of the RecQ helicase family, is required for the maintenance of genome integrity. RecQ4 has been shown to promote the following two DNA double-strand break (DSB) repair pathways: non-homologous end joining (NHEJ) and homologous recomb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6faa314db032c47582e0fc72e5c575a
https://pubmed.ncbi.nlm.nih.gov/33845136
https://pubmed.ncbi.nlm.nih.gov/33845136
Publikováno v:
Biochemical and Biophysical Research Communications. 490:1375-1380
The initiation of DNA replication is strictly regulated by multiple mechanisms to ensure precise duplication of chromosomes. In higher eukaryotes, activity of the Cdt1 protein is temporally regulated during the cell cycle, and deregulation of Cdt1 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6f0a26446904507ed649e59b592a20
https://doi.org/10.1016/j.bbrc.2017.07.034
https://doi.org/10.1016/j.bbrc.2017.07.034
Autor:
Masayuki Seki, Shusuke Tada, Yuta Nakazaki, Takemi Enomoto, Takashi Tsuyama, Mikiko Takahashi
Publikováno v:
Biochemical and biophysical research communications. 470(2)
Cdt1 is a protein essential for initiation of DNA replication; it recruits MCM helicase, a core component of the replicative DNA helicase, onto replication origins. In our previous study, we showed that addition of excess Cdt1 inhibits nascent strand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79cf24f2c5648093c27ad0cf13327ac6
https://pubmed.ncbi.nlm.nih.gov/26773501
https://pubmed.ncbi.nlm.nih.gov/26773501
Autor:
Jie Hye Lee, Yunje Cho, Bulat I. Khayrutdinov, P. Andrew Karplus, Takemi Enomoto, Jung-Soon Ko, Kyoung-Seok Ryu, Eunha Hwang, Peter Güntert, Young Mi Yun, Jeong Joo Kim, Shusuke Tada, Hae-Kap Cheong, Takashi Tsuyama, Won Jin Bae, Chaejoon Cheong, Young Ho Jeon
Publikováno v:
Protein Science. 18:2252-2264
In eukaryotic replication licensing, Cdt1 plays a key role by recruiting the MCM2-7 complex onto the origin of chromosome. The C-terminal domain of mouse Cdt1 (mCdt1C), the most conserved region in Cdt1, is essential for licensing and directly intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2d727931eecace7a46cd23f118ac050
https://doi.org/10.1002/pro.236
https://doi.org/10.1002/pro.236
Autor:
Takemi Enomoto, Masayuki Seki, Saori Watanabe, Ayako Aoki, Takashi Tsuyama, Shusuke Tada, Yunje Cho
Publikováno v:
Molecular Biology of the Cell. 20:937-947
Excess Cdt1 reportedly induces rereplication of chromatin in cultured cells and Xenopus egg extracts, suggesting that the regulation of Cdt1 activity by cell cycle-dependent proteolysis and expression of the Cdt1 inhibitor geminin is crucial for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db75e13bbca59a0dbfb87d34af54045d
https://doi.org/10.1091/mbc.e08-06-0613
https://doi.org/10.1091/mbc.e08-06-0613
Autor:
Fumio Hanaoka, Takahiko Seki, Katsutoshi Inou, Takayuki Kobayashi, Masayuki Seki, Shusuke Tada, Takemi Enomoto, Yuji Kumata, Takashi Tsuyama, Keiji Kimura
Publikováno v:
Biochemical and Biophysical Research Communications. 351:935-939
Smc6, a member of the structural maintenance of chromosomes (SMC) family of proteins, forms a complex with related Smc5. Genetic analyses of yeast have demonstrated the involvement of Smc6 in DNA repair and checkpoint responses. In this study, we inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076d451219f866c157cc57e02dd2a6f1
https://doi.org/10.1016/j.bbrc.2006.10.133
https://doi.org/10.1016/j.bbrc.2006.10.133
Autor:
Takashi Tsuyama, Asako Sugimoto, Takemi Enomoto, Shusuke Tada, Ken-ichiro Yanagi, Yumi Iida, Toshihiko Eki, Takeshi Mizuno, Fumio Hanaoka
Publikováno v:
Journal of Biological Chemistry. 280:19689-19694
Cdt1 is an essential component for the assembly of a pre-replicative complex. Cdt1 activity is inhibited by geminin, which also participates in neural development and embryonic differentiation in many eukaryotes. Although Cdt1 homologues have been id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d502e76c52df33d2e313aa43599d88
https://doi.org/10.1074/jbc.c500070200
https://doi.org/10.1074/jbc.c500070200
Publikováno v:
Nucleic Acids Research
Replication origins are licensed for a single initiation event by the loading of Mcm2-7 proteins during late mitosis and G1. Sequential associations of origin recognition complex, Cdc6 and Mcm2-7 are essential for completion of the licensing. Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca85c63fe32393a9a382a614b01207a2
https://doi.org/10.1093/nar/gki226
https://doi.org/10.1093/nar/gki226
Autor:
Takayuki Kobayashi, Shusuke Tada, Takashi Tsuyama, Masayuki Seki, Takemi Enomoto, Hiromu Murofushi
Publikováno v:
Journal of Cell Science. 115:3159-3169
金沢大学大学院自然科学研究科 信頼性システム工学
The response to DNA damage was analyzed using a cell-free system consisting of Xenopus egg extract and demembranated sperm nuclei. In the absence of DNA-damaging agents, dete
The response to DNA damage was analyzed using a cell-free system consisting of Xenopus egg extract and demembranated sperm nuclei. In the absence of DNA-damaging agents, dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bcb59135b656705b96ba007f53a971b
https://doi.org/10.1242/jcs.115.15.3159
https://doi.org/10.1242/jcs.115.15.3159