Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Takashi Shimbo"'
Autor:
Kyota Ishibashi, Kentaro Ikegami, Takashi Shimbo, Eiji Sasaki, Tomomi Kitayama, Yuzuru Nakamura, Takahiro Tsushima, Yasuyuki Ishibashi, Katsuto Tamai
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Cell heterogeneity in the mouse anterior cruciate ligament (ACL) and medial collateral ligament (MCL) is demonstrated using single-cell analysis with three types of fibroblasts identified, expressing Col14a1, Col12a1, or Col22a1.
Externí odkaz:
https://doaj.org/article/e4b2f4597bd244559f072d3025bd8dbf
Autor:
Ayumu Taniguchi, Kazuya Miyashita, Shota Fukae, Ryo Tanaka, Mami Nishida, Tomomi Kitayama, Yuya Ouchi, Takashi Shimbo, Shigeaki Nakazawa, Kazuaki Yamanaka, Ryoichi Imamura, Katsuto Tamai, Norio Nonomura
Publikováno v:
Biochemistry and Biophysics Reports, Vol 33, Iss , Pp 101433- (2023)
Ischemia-reperfusion injury (IRI) causes massive tissue damage. Renal IRI is the most common type of acute renal injury, and the defects caused by it may progress to chronic kidney disease (CKD). Rodent models of renal IRI, with various patterns, hav
Externí odkaz:
https://doaj.org/article/9e5817ea575e4af7972e106a272812cd
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Abstract is missing (Short communication)
Externí odkaz:
https://doaj.org/article/e92c6900e46d401490a698bfbe2325d6
Autor:
Shunsuke Nojiri, Atsunori Tsuchiya, Kazuki Natsui, Suguru Takeuchi, Takayuki Watanabe, Yuichi Kojima, Yusuke Watanabe, Hiroteru Kamimura, Masahiro Ogawa, Satoko Motegi, Takahiro Iwasawa, Takeki Sato, Masaru Kumagai, Yui Ishii, Tomomi Kitayama, Yu-Tung Li, Yuya Ouchi, Takashi Shimbo, Masaaki Takamura, Katsuto Tamai, Shuji Terai
Publikováno v:
Inflammation and Regeneration, Vol 41, Iss 1, Pp 1-15 (2021)
Abstract The liver has a high regenerative ability and can induce spontaneous regression of fibrosis when early liver damage occurs; however, these abilities are lost when chronic liver damage results in decompensated cirrhosis. Cell therapies, such
Externí odkaz:
https://doaj.org/article/b12286f4bc7841a399f9b7b2e8ece5b3
Autor:
Yen-Ting Ho, Takashi Shimbo, Edward Wijaya, Tomomi Kitayama, Satoshi Takaki, Kentaro Ikegami, Kazuya Miyashita, Yuya Ouchi, Eiichi Takaki, Ryoma Yamamoto, Yasufumi Kaneda, Katsuto Tamai
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 547-566 (2021)
Background & Aims: Proper resolution of inflammation is essential to maintaining homeostasis, which is important as a dysregulated inflammatory response has adverse consequences, even being regarded as a hallmark of cancer. However, our picture of dy
Externí odkaz:
https://doaj.org/article/23fc3a8d6ed64cb48e110a16004fa035
Autor:
Takashi Shimbo, Machika Kawamura, Edward Wijaya, Eiichi Takaki, Yasufumi Kaneda, Katsuto Tamai
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background Deciphering the 3D structure of the genome is essential for elucidating the regulatory mechanisms of gene expression in detail. Existing methods, such as chromosome conformation capture (3C) and Hi-C have enabled the identificatio
Externí odkaz:
https://doaj.org/article/1f6a5882e6454ffca48163226a1e0858
Autor:
Sara A. Grimm, Takashi Shimbo, Motoki Takaku, James W. Thomas, Scott Auerbach, Brian D. Bennett, John R. Bucher, Adam B. Burkholder, Frank Day, Ying Du, Christopher G. Duncan, John E. French, Julie F. Foley, Jianying Li, B. Alex Merrick, Raymond R. Tice, Tianyuan Wang, Xiaojiang Xu, NISC Comparative Sequencing Program, Pierre R. Bushel, David C. Fargo, James C. Mullikin, Paul A. Wade
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
DNA methylation is an epigenetic mark involved in gene regulation. Here the authors investigate the extent to which genetics, sex and pregnancy influence genomic DNA methylation in mice, providing evidence of the stability of CpG methylation across g
Externí odkaz:
https://doaj.org/article/f487b8a5e96d4b4596531537eeed2656
Publikováno v:
Genomics Data, Vol 7, Iss , Pp 173-174 (2016)
Chromatin accessibility is tightly regulated by multiple factors/mechanisms to establish different cell type-specific gene expression programs from a single genome. Dysregulation of this process can lead to diseases including cancer. The Mi-2/nucleos
Externí odkaz:
https://doaj.org/article/ef6f31fb7dd849eb8e2080f40647a96a
Autor:
Roberta Menafra, Arie B Brinkman, Filomena Matarese, Gianluigi Franci, Stefanie J J Bartels, Luan Nguyen, Takashi Shimbo, Paul A Wade, Nina C Hubner, Hendrik G Stunnenberg
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99603 (2014)
MBD2 is a subunit of the NuRD complex that is postulated to mediate gene repression via recruitment of the complex to methylated DNA. In this study we adopted an MBD2 tagging-approach to study its genome wide binding characteristics. We show that in
Externí odkaz:
https://doaj.org/article/30def5513cdb4127ac413b58958e774d
Autor:
Takashi Shimbo, Ying Du, Sara A Grimm, Archana Dhasarathy, Deepak Mav, Ruchir R Shah, Huidong Shi, Paul A Wade
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1004028 (2013)
The Mi-2/nucleosome remodeling and histone deacetylase (NuRD) complex is a multiprotein machine proposed to regulate chromatin structure by nucleosome remodeling and histone deacetylation activities. Recent reports describing localization of NuRD pro
Externí odkaz:
https://doaj.org/article/6ef3b607ead84eed8edde246fcc1b9d1