Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Takashi SHINOHARA"'
Autor:
Yuma ADACHI, Masashi YOKOTA, Tetsuya AKAGI, Shujiro DOHTA, Feifei CHO, Takashi SHINOHARA, Takumi ISHIBASHI
Publikováno v:
Journal of Advanced Mechanical Design, Systems, and Manufacturing, Vol 18, Iss 5, Pp JAMDSM0069-JAMDSM0069 (2024)
A home healthcare support device that can give passive exercise to keep the treated joint moving area has been desired. In the previous study, a Tetrahedral-shaped Flexible Pneumatic Actuator (it is called TFPA for short) using three extension type f
Externí odkaz:
https://doaj.org/article/06540e1b72924c2d89b4e88c7f42de6a
Autor:
Misuzu IDE, Ibuki SAITO, Makoto SANBO, Mito KANATSU-SHINOHARA, Takashi SHINOHARA, Masumi HIRABAYASHI, Shinichi HOCHI
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 4, Pp 254-258 (2024)
Intracytoplasmic sperm injection (ICSI) is clinically used to treat obstructive/nonobstructive azoospermia. This study compared the efficacy of ICSI with cauda epididymal and testicular sperm in Wistar (WI) and Brown-Norway (BN) rats. The transfer of
Externí odkaz:
https://doaj.org/article/ea67c67658734176a1ef1eddf683a236
Publikováno v:
The Journal of Reproduction and Development, Vol 69, Iss 6, Pp 347-355 (2023)
Spermatogonial stem cells (SSCs) possess a unique ability to recolonize the seminiferous tubules. Upon microinjection into the adluminal compartment of the seminiferous tubules, SSCs transmigrate through the blood-testis barrier (BTB) to the basal co
Externí odkaz:
https://doaj.org/article/7ad7ba5e83cc409e81df7dee78f7fbf7
Autor:
Takafumi Matsumura, Kumiko Katagiri, Tatsuma Yao, Yu Ishikawa-Yamauchi, Shino Nagata, Kiyoshi Hashimoto, Takuya Sato, Hiroshi Kimura, Takashi Shinohara, Makoto Sanbo, Masumi Hirabayashi, Takehiko Ogawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract An in vitro spermatogenesis method using mouse testicular tissue to produce fertile sperm was established more than a decade ago. Although this culture method has generally not been effective in other animal species, we recently succeeded in
Externí odkaz:
https://doaj.org/article/840c25e053eb49ef8f12a549efe24686
Autor:
Bat-Erdene Jargalsaikhan, Masanaga Muto, Youngeun Been, Shoma Matsumoto, Eiichi Okamura, Tadanobu Takahashi, Yutaka Narimichi, Yuuki Kurebayashi, Hideyuki Takeuchi, Takashi Shinohara, Ryo Yamamoto, Masatsugu Ema
Publikováno v:
Viruses, Vol 16, Iss 6, p 827 (2024)
A gene delivery system utilizing lentiviral vectors (LVs) requires high transduction efficiency for successful application in human gene therapy. Pseudotyping allows viral tropism to be expanded, widening the usage of LVs. While vesicular stomatitis
Externí odkaz:
https://doaj.org/article/255f316f770a4b36b37e3597637ec09b
Publikováno v:
The Journal of Reproduction and Development, Vol 68, Iss 6, Pp 369-376 (2022)
Oogenesis depends on close interactions between oocytes and granulosa cells. Abnormal signaling between these cell types can result in infertility. However, attempts to manipulate oocyte-granulosa cell interactions have had limited success, likely du
Externí odkaz:
https://doaj.org/article/14f7e4bcee5f4e53a659d761d5c7fc65
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Germline mutations underlie genetic diversity and species evolution. Previous studies have assessed the theoretical mutation rates and spectra in germ cells mostly by analyzing genetic markers and reporter genes in populations and pedigrees.
Externí odkaz:
https://doaj.org/article/b8dd418157e94e4c8b68cf453b792d45
Publikováno v:
The Journal of Reproduction and Development, Vol 66, Iss 4, Pp 341-349 (2020)
The spermatogonial stem cell (SSC) population in testis is small, and the lack of SSC markers has severely handicapped research on these cells. During our attempt to identify genes involved in SSC aging, we found that CD2 is expressed in cultured SSC
Externí odkaz:
https://doaj.org/article/6d545fd55764467cb45daaf7ee25b59a
Publikováno v:
Stem Cell Reports, Vol 14, Iss 3, Pp 447-461 (2020)
Summary: Spermatogonial stem cells (SSCs) serve as a resource for producing genetically modified animals. However, genetic manipulation of SSCs has met with limited success. Here, we show efficient gene transfer into SSCs via a lentivirus (FV-LV) usi
Externí odkaz:
https://doaj.org/article/17782f72f90644aeb1fbc9fac0895486
Autor:
Tadashi Yamamuro, Shuhei Nakamura, Yu Yamano, Tsutomu Endo, Kyosuke Yanagawa, Ayaka Tokumura, Takafumi Matsumura, Kiyonori Kobayashi, Hideto Mori, Yusuke Enokidani, Gota Yoshida, Hitomi Imoto, Tsuyoshi Kawabata, Maho Hamasaki, Akiko Kuma, Sohei Kuribayashi, Kentaro Takezawa, Yuki Okada, Manabu Ozawa, Shinichiro Fukuhara, Takashi Shinohara, Masahito Ikawa, Tamotsu Yoshimori
Publikováno v:
PLoS Genetics, Vol 17, Iss 8 (2021)
Autophagy degrades unnecessary proteins or damaged organelles to maintain cellular function. Therefore, autophagy has a preventive role against various diseases including hepatic disorders, neurodegenerative diseases, and cancer. Although autophagy i
Externí odkaz:
https://doaj.org/article/d2de1c9609cc4eabada556ef6ddc88f3