Zobrazeno 1 - 10
of 1 051
pro vyhledávání: '"Takashi Okada"'
Autor:
Tzuyao Lo, Itaru Kushima, Hiroki Kimura, Branko Aleksic, Takashi Okada, Hidekazu Kato, Toshiya Inada, Yoshihiro Nawa, Youta Torii, Maeri Yamamoto, Ryo Kimura, Yasuko Funabiki, Hirotaka Kosaka, Shusuke Numata, Kiyoto Kasai, Tsukasa Sasaki, Shigeru Yokoyama, Toshio Munesue, Ryota Hashimoto, Yuka Yasuda, Michiko Fujimoto, Masahide Usami, Masanari Itokawa, Makoto Arai, Kazutaka Ohi, Toshiyuki Someya, Yuichiro Watanabe, Jun Egawa, Tsutomu Takahashi, Michio Suzuki, Hidenori Yamasue, Nakao Iwata, Masashi Ikeda, Norio Ozaki
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 1, Pp 42-50 (2024)
Abstract Aim The present study aimed to examine the association between copy number variations (CNVs) in parkin (PRKN) and schizophrenia (SCZ) and autism spectrum disorder (ASD) in a large case–control sample. Method Array comparative genomic hybri
Externí odkaz:
https://doaj.org/article/7c5247e49f9446b48f67640ae93b6ce0
Autor:
Noa Tsujii, Kosuke Okazaki, Hiroaki Kihara, Masahide Usami, Junichi Fujita, Fumie Horiuchi, Takashi Okada, Hideki Negoro
Publikováno v:
PCN Reports, Vol 3, Iss 2, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/4247696fa2bb403fa406079fc7a3e39f
Autor:
Yuko Nitahara-Kasahara, Guillermo Posadas-Herrera, Kunio Hirai, Yuki Oda, Noriko Snagu-Miyamoto, Yuji Yamanashi, Takashi Okada
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
IntroductionDuchenne muscular dystrophy (DMD) is a genetic disorder caused by mutations in the dystrophin-encoding gene that leads to muscle necrosis and degeneration with chronic inflammation during growth, resulting in progressive generalized weakn
Externí odkaz:
https://doaj.org/article/e2a973ee24df45b998f81b57b85e6b1a
Autor:
QinQin Yu, Joao A Ascensao, Takashi Okada, COVID-19 Genomics UK (COG-UK) Consortium, Olivia Boyd, Erik Volz, Oskar Hallatschek
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012090 (2024)
Genetic drift in infectious disease transmission results from randomness of transmission and host recovery or death. The strength of genetic drift for SARS-CoV-2 transmission is expected to be high due to high levels of superspreading, and this is ex
Externí odkaz:
https://doaj.org/article/54499924c55b4d6fbf11f47395fc77d6
Autor:
Yuki Motomura, Sayuri Hayashi, Ryousei Kurose, Hiroki Yoshida, Takashi Okada, Shigekazu Higuchi
Publikováno v:
Journal of Physiological Anthropology, Vol 42, Iss 1, Pp 1-14 (2023)
Abstract Background The aim of this study was to examine the effect of others’ gaze on an observer’s microsaccades. We also aimed to conduct preliminary investigations on the relationship between the microsaccadic response to a gaze and a gazer
Externí odkaz:
https://doaj.org/article/81f4742ef07d49749f64e158816b49ee
Autor:
Masafumi Arakawa, Yuki Sakamoto, Yoshitaka Miyagawa, Chikako Nito, Shiro Takahashi, Yuko Nitahara-Kasahara, Satoshi Suda, Yoshiyuki Yamazaki, Mashito Sakai, Kazumi Kimura, Takashi Okada
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 333-349 (2023)
Induced pluripotent stem cell-derived mesenchymal stem cells (iMSCs) hold great promise as a cell source for transplantation into injured tissues to alleviate inflammation. However, the therapeutic efficacy of iMSC transplantation for ischemic stroke
Externí odkaz:
https://doaj.org/article/de77c9267be3494292d9022ead8fa26d
Autor:
Kouhei Yoshida, Yuji Tsunekawa, Kento Kurihara, Kazuya Watanabe, Yuriko Makino-Manabe, Mikako Wada, Toru Tanaka, Teruhiko Ide, Takashi Okada
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101157- (2023)
Adeno-associated virus (AAV) is a major viral vector used in gene therapy. There are multiple AAV serotypes, and many engineered AAV serotypes are developed to alter their tissue tropisms with capsid modification. The universal AAV receptor (AAVR) is
Externí odkaz:
https://doaj.org/article/e72d7deef5274fb99297c3e73c7dce92
Autor:
Yuko Nitahara-Kasahara, Soya Nakayama, Koichi Kimura, Sho Yamaguchi, Yuko Kakiuchi, Chikako Nito, Masahiro Hayashi, Tomoyuki Nakaishi, Yasuyoshi Ueda, Takashi Okada
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Background Duchenne muscular dystrophy (DMD) is an incurable genetic disease characterized by degeneration and necrosis of myofibers, chronic inflammation, and progressive muscle weakness resulting in premature mortality. Immunosuppressive m
Externí odkaz:
https://doaj.org/article/c3f1f3dc487f4608aa4c00ce14cd3e31
Autor:
Shigeki Takai, Naohiko Nakanishi, Isao Yokota, Kojiro Imai, Ayumu Yamada, Takanori Kawasaki, Takeru Kasahara, Takashi Okada, Takahisa Sawada, Satoaki Matoba
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Rivaroxaban, a direct oral anticoagulant, is effective against venous thromboembolism (VTE) recurrence without increasing the risk of major bleeding in patients with cancer-associated venous thromboembolism (CAT). However, its clot regressio
Externí odkaz:
https://doaj.org/article/ee28948199134b849326e1e283210bf3
Autor:
Sohsuke Meshitsuka, Ryo Ninomiya, Tokiko Nagamura-Inoue, Takashi Okada, Muneyoshi Futami, Arinobu Tojo
Publikováno v:
Regenerative Therapy, Vol 21, Iss , Pp 442-452 (2022)
Introduction: Mesenchymal stromal cells (MSCs) hold the potential for application as cellular therapy products; however, there are many problems that need to be addressed before the use in clinical settings, these include the heterogeneity of MSCs, s
Externí odkaz:
https://doaj.org/article/23b9bdd802e2484993f3745bd0c5e6cd