Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Takashi Okabe"'
Autor:
Maki Todo, Gou Kaneko, Suguru Shirotake, Yuki Shimada, Shintaro Nakano, Takashi Okabe, Shiho Ishikawa, Masafumi Oyama, Koshiro Nishimoto
Publikováno v:
IJU Case Reports, Vol 3, Iss 1, Pp 17-20 (2020)
Introduction Pembrolizumab cause immune‐related adverse events. We herein report a case of advanced bladder cancer, who treated with pembrolizumab and exhibited intriguing clinical course. Case presentation A 63‐year‐old man with bladder carcin
Externí odkaz:
https://doaj.org/article/4179b20a6c1540ad9fc8050acc34a5ec
Autor:
Kent Kanao, Takayuki Takahashi, Yuta Umezawa, Takashi Okabe, Go Kaneko, Suguru Shirotake, Koshiro Nishimoto, Masafumi Oyama
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Background The treatment landscape for men with metastatic hormone-naïve prostate cancer (mHNPC) has dramatically changed with the approval of next-generation anti-androgen drugs. We compared the treatment efficacy of abiraterone with that of combin
Externí odkaz:
https://doaj.org/article/259206cbcff24eb69c7ef6fc5e23e625
Autor:
Keitaro Watanabe, Suguru Shirotake, Yuta Umezawa, Takayuki Takahashi, Takeshi Yamanaka, Noriaki LSanto, Takashi Okabe, Gou Kaneko, Katsuhiro Sano, Masanori Yasuda, Kent Kanao, Masafumi Oyama, Koshiro Nishimoto
Publikováno v:
IJU Case Reports, Vol 2, Iss 6, Pp 313-316 (2019)
Introduction Transurethral resection of bladder tumor is widely used in combination with photodynamic diagnosis to treat non‐muscle invasive bladder cancer. We experienced an intriguing case, in which bladder cancer infiltrated into the right urete
Externí odkaz:
https://doaj.org/article/1fc0d011ad804f9dafba6f030e6af2be
Autor:
Maki Todo, Hideyuki Kondo, Taiki Hayashi, Tsukasa Masuda, Takashi Okabe, Go Kaneko, Masafumi Oyama, Suguru Shirotake, Koshiro Nishimoto
Publikováno v:
IJU Case Reports, Vol 2, Iss 5, Pp 272-275 (2019)
Introduction Pazopanib, a tyrosine kinase inhibitor, and nivolumab, an immune checkpoint inhibitor, are both considered to cause hepatotoxicity with different pathophysiology. We report a case in which a patient died of severe hepatotoxicity who was
Externí odkaz:
https://doaj.org/article/35750e8ec9644e23a5f653f671d2810c
Publikováno v:
Earth, Planets and Space, Vol 70, Iss 1, Pp 1-9 (2018)
Abstract A continuous water injection test was conducted to halt the reduction in steam production in the Okuaizu Geothermal Field, Japan. Understanding the factors triggering microseismicity associated with water injection is essential to ensuring e
Externí odkaz:
https://doaj.org/article/be66dba006ac4ddd997f78419668843f
Autor:
Rohit Chavan, Nadia Preitner, Takashi Okabe, Laureen Mansencal Strittmatter, Cheng Xu, Jürgen A. Ripperger, Nelly Pitteloud, Urs Albrecht
Publikováno v:
Biology Open, Vol 6, Iss 1, Pp 1-7 (2017)
The circadian clock contributes to the timing of many body functions including metabolism and reproduction. The hepatokine fibroblast growth factor 21 (FGF21) is a critical metabolic regulator involved in modulation of fertility. Here we show that la
Externí odkaz:
https://doaj.org/article/92a91f8b82374ac0b77f1d81e7d4ec8f
Autor:
Rohit Chavan, Céline Feillet, Sara S. Fonseca Costa, James E. Delorme, Takashi Okabe, Jürgen A. Ripperger, Urs Albrecht
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Food anticipation is thought to be initiated by the central clock in the brain. Here the authors show that the peripheral organs initiate this process by showing that liver-specific deletion of Per2 can inhibit food anticipation by interfering with
Externí odkaz:
https://doaj.org/article/77b85e39911340e4b93f1f36a10c9087
Autor:
Hideyuki Kondo, Suguru Shirotake, Takashi Okabe, Soichi Makino, Koshiro Nishimoto, Masafumi Oyama
Publikováno v:
Case Reports in Urology, Vol 2018 (2018)
A 75-year-old Japanese male was referred to our institution for the evaluation of a left ureteral tumor in the ureterovesical junction. Computed tomography and pathologic examination under ureteroscopy revealed an invasive left ureteral urothelial ca
Externí odkaz:
https://doaj.org/article/6730a3b5ac1244d38a33f75fd028a596
Autor:
Koichi Murakami, Hironori Ueno, Takashi Okabe, Toshiya Kagoo, Saigen Boku, Takahiro Yano, Akihiro Yokoyama
Publikováno v:
Hematology Reports, Vol 9, Iss 2 (2017)
Allogeneic stem cell transplantation (allo-SCT) is the only curative option for myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Azacitidine (AZA) has a good toxicity profile compared with intensive chemotherapy and can be considered
Externí odkaz:
https://doaj.org/article/56e881760e1d4ddda522c94337653d07
Autor:
Takashi Okabe, Megumi Kumagai, Yoshihiro Nakajima, Suguru Shirotake, Kiichiro Kodaira, Masafumi Oyama, Munehisa Ueno, Masaaki Ikeda
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109693 (2014)
In mammals, the circadian rhythm central generator consists of interactions among clock genes, including Per1/2/3, Cry1/2, Bmal1, and Clock. Circadian rhythm disruption may lead to increased risk of cancer in humans, and deregulation of clock genes h
Externí odkaz:
https://doaj.org/article/72d8721dc05a44ef8bbd201ada9b2035