Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Takashi Ohnuki"'
Publikováno v:
Microbiology resource announcements. 11(2)
We analyzed the bacterial diversity of root nodule and rhizosphere soil samples of edamame collected in Ebina, Japan. The major population identified from the nodules belonged to the genus Bradyrhizobium , and the rhizosphere soil in the open field h
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:199-203
We herein report a practical one-step glucuronidation method by biotransformation using Streptomyces sp. SANK 60895. This novel direct method of biotransformation has been shown to be more practical and scalable for glucuronidation than previously re
Autor:
Chitose Tashiro, Takashi Ohnuki, Shosuke Yamamura, Yoshiyuki Sawai, Yuichiro Shibazaki, Minoru Ueda
Publikováno v:
Bioscience, biotechnology, and biochemistry. 62(11)
cis-p-Coumaroylagmatine (1) was isolated from Albizzia julibrissin Durazz, a nyctinastic plant, as a leaf-opening substance. The compound was quite effective for opening the plant leaves at 5×10(-6) M at night, but was not effective for other nyctin
Autor:
Wataru Tomisato, Keisuke Suzuki, Ryotaku Inoue, Yumi Kawase, Takashi Izumi, Keiko Oshima, Hiroshi Yuita, Takaichi Shimozato, Katsuyoshi Nakajima, Takahide Nishi, Shojiro Miyazaki, Futoshi Nara, Yukiko Iio, Takashi Kagari, Shin-ichi Inaba, Takashi Ohnuki, Toshiyasu Takemoto, Hiromi Doi
Publikováno v:
ACS Medicinal Chemistry Letters. 2:368-372
CS-0777 (3) is phosphorylated in vivo, and the phosphate of CS-0777 (CS-0777-P) (4) acts as a selective S1P receptor-1 (S1P1) modulator. We report herein the synthesis of CS-0777 and CS-0777-P, pharmacological effects such as S1P1 and S1P3 agonist ac
Autor:
Shiho Kozuma, Tatsuya Yano, Yasunori Ono, Takashi Ohnuki, Toshio Takatsu, Toshihiro Suzuki, Yasumasa Ogawa
Publikováno v:
The Journal of Antibiotics. 62:545-549
In the course of screening for antifungal agents, we have discovered eight novel compounds, haplofungin A, B, C, D, E, F, G and H, from a culture broth of the fungus strain Lauriomyces bellulus SANK 26899. Haplofungins are composed of an arabinonic a
Autor:
Arai Masatoshi, Masatoshi Inukai, Shunichi Miyakoshi, Toshio Takatsu, Yasunori Muramatsu, Takashi Ohnuki, Michiko Miyazawa Ishii, Yasumasa Ogawa
Publikováno v:
The Journal of Antibiotics. 56:259-267
Novel derivatives of capuramycin were obtained when 10 mM of 2-aminoethyl-L-cysteine (AEC), an inhibitor of aspartokinase, was added to the culture of Streptomyces griseus SANK 60196, the producer of A-500359. They were purified from the culture filt
Autor:
Ryuzo Enokita, Takashi Ohnuki, Yasunori Muramatsu, Toshihiro Suzuki, Masatoshi Inukai, Shinya Tsutsumi, Yasumasa Ogawa, Michiko Miyazawa Ishii, Masaaki Kizuka, Toshio Takatsu, Akiko Muramatsu, Arai Masatoshi
Publikováno v:
The Journal of Antibiotics. 56:243-252
In the course of our screening for bacterial phospho-N-acetylmuramyl-pentapeptide-translocase (translocase I: EC 2.7.8.13) inhibitors, we found inhibitory activity in the cultured broth of the strain identified as Streptomyces griseus SANK 60196. The
Publikováno v:
Scopus-Elsevier
Most leguminous plants close their leaves in the evening, as if to sleep, and open them early in the morning according to the circadian rhythm controlled by a biological clock. Extensive studies on nyctinastic plants led to the isolation of a variety
Autor:
Yasuhiro, Nakagami, Kayoko, Masuda, Emiko, Hatano, Tatsuya, Inoue, Takuya, Matsuyama, Mayumi, Iizuka, Yasunori, Ono, Takashi, Ohnuki, Yoko, Murakami, Masaru, Iwasaki, Kazuhiro, Yoshida, Yuji, Kasuya, Satoshi, Komoriya
Publikováno v:
British journal of pharmacology. 172(5)
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a redox-sensitive transcription factor that binds to antioxidant response elements located in the promoter region of genes encoding many antioxidant enzymes and phase II detoxifying enzymes. Activ
Publikováno v:
Synlett. 2009:910-912
We report herein practical phosphorylation methods for a,a-disubstituted α-amino alcohol derivatives which act as Sl P i receptor agonists. A novel direct phosphorylation method for a,a-disubstituted α-amino alcohol derivatives by biotransformation