Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Takashi Odawara"'
Autor:
Daisuke Miyahara, Satoshi Fukagawa, Shin'ichiro Yasunaga, Takahiro Katsuda, Kohei Miyata, Sung Ouk Nam, Takashi Odawara, Fusanori Yotsumoto, Toyokazu Ishikawa, Shingo Miyamoto, Sadao Manabe
Publikováno v:
Anticancer Research. 37
Advanced lung cancer is one of the most lethal malignancies. Many anticancer agents have been developed for lung cancer with epidermal growth factor receptor (EGFR) mutations, but its prognosis remains extremely poor. The development of molecularly-t
Autor:
Sadao Manabe, Toyokazu Ishikawa, Shin'ichiro Yasunaga, Satoshi Fukagawa, Fusanori Yotsumoto, Shingo Miyamoto, Takashi Odawara
Publikováno v:
Anticancer research. 37(7)
Background Patients with ovarian cancer with high levels of heparin-binding epidermal growth factor-like growth factor have a poor prognosis. Here we assessed the pharmacokinetics and tumour-inhibiting effects of cross-reacting material 197, produced
Autor:
Fusanori, Yotsumoto, Satoshi, Fukagawa, Kohei, Miyata, Sung Ouk, Nam, Takahiro, Katsuda, Daisuke, Miyahara, Takashi, Odawara, Sadao, Manabe, Toyokazu, Ishikawa, Shin'ichiro, Yasunaga, Shingo, Miyamoto
Publikováno v:
Anticancer research. 37(7)
Advanced lung cancer is one of the most lethal malignancies. Many anticancer agents have been developed for lung cancer with epidermal growth factor receptor (EGFR) mutations, but its prognosis remains extremely poor. The development of molecularly-t
BK-UM in patients with recurrent ovarian cancer or peritoneal cancer: a first-in-human phase-I study
Autor:
Tomoya Hikita, Daisuke Miyahara, Hiroaki Nishikawa, Masahide Kuroki, Yoshinobu Okuno, Shingo Miyamoto, Miyako Maehara, Kenji Ishitsuka, Yasushi Takamatsu, Minako Ohishi, Tatsuya Fukami, Kazuhiro Maeda, Fusanori Yotsumoto, Haruhiko Kondo, Shinsuke Nishino, Kazuo Tamura, Akira Matsunaga, Keijiro Saku, Yoshio Tsuboi, Sadao Manabe, Toshiyuki Yoshizato, Kyoko Shirota, Satoshi Fukagawa, Takahiro Katsuta, Ryo Iwamoto, Hiroto Mizushima, Kohei Miyata, Taeko Ueda, Ayako Sanui, Sung Ouk Nam, Toru Hachisuga, Takashi Odawara, Eisuke Mekada, Toyokazu Ishikawa
Publikováno v:
BMC Cancer
Background BK-UM (CRM197) is a mutant form of diphtheria toxin and a specific inhibitor of heparin-binding epidermal growth factor-like growth factor (HB-EGF). We assessed the safety, pharmacokinetics, recommended dose, and efficacy of BK-UM in patie
Autor:
Sung Ouk, Nam, Fusanori, Yotsumoto, Kohei, Miyata, Satoshi, Fukagawa, Takashi, Odawara, Sadao, Manabe, Toyokazu, Ishikawa, Masahide, Kuroki, Shin'ichiro, Yasunaga, Shingo, Miyamoto
Publikováno v:
Anticancer research. 36(7)
Heparin-binding epidermal growth factor-like growth factor (HB-EGF), which belongs to the epidermal growth factor family, is a rational therapeutic target for triple-negative breast cancer (TNBC). This study aimed to assess the anti-tumor efficacy of
Autor:
Noriaki Hosoya, Michiko Koga, Takashi Odawara, Ai Kawana-Tachikawa, Toshiyuki Miura, Tadashi Kikuchi, Aikichi Iwamoto, Tomohiko Koibuchi, Takeshi Fujii, Naoko Miyazaki, Hitomi Nakamura
Publikováno v:
Journal of Infection and Chemotherapy. 17:105-110
Drug-resistant virus infection has been a major hurdle in the management of human immunodeficiency virus type 1 (HIV-1) infection. Recently, three novel antiretrovirals [raltegravir (RAL), etravirine (ETR), and darunavir (DRV)] were introduced into t
Autor:
Hideki Uchiumi, Seiji Okada, Akira Watanabe, Seiji Saito, Hirokazu Nagai, Toshikazu Miyakawa, Mihoko Yotsumoto, Soichiro Takahama, Mitsuru Konishi, Takashi Odawara, Masao Tateyama, Atsushi Ajisawa, Tomoko Uehira, Toshiyuki Kambe, Shotaro Hagiwara, Tomoyuki Watanabe
Publikováno v:
European Journal of Haematology. 84:499-505
Primary central nervous system lymphoma (PCNSL) related to acquired immunodeficiency syndrome (AIDS) is a lethal disorder, but the recent application of highly active antiretroviral therapy (HAART) has significantly improved prognosis. This retrospec
Autor:
Toshiyuki Miura, Michiko Koga, Hitomi Nakamura, Takashi Odawara, Aikichi Iwamoto, Takeshi Fujii, Tomohiko Koibuchi, David Heckerman, Ai Kawana-Tachikawa
Publikováno v:
Microbiology and Immunology. 54:196-205
HLA class I allele types have differential impacts on the level of the pVL and outcome of HIV-1 infection. While accumulations of CTL escape mutations at population levels have been reported, their actual impact on the level of the pVL remains unknow
Autor:
Eriko Miyazaki, Jun-ichi Nunoya, Ai Kawana-Tachikawa, Takeshi Fujii, George F. Gao, Aikichi Iwamoto, Yi Shi, Takashi Odawara, Mariko Tomizawa
Publikováno v:
AIDS. 23:651-660
Objective: In peripheral blood mononuclear cells (PBMCs) from HIV-1-positive patients, we sought to identify CD8 + T-cell populations and the corresponding T-cell receptor (TCR) repertoires that react to an immunogenic cytotoxic T lymphocyte (CTL) ep
Autor:
Kazushige Washizaki, Aikichi Iwamoto, Takeshi Fujii, Takeshi Matsumura, Takashi Odawara, Takuya Maeda
Publikováno v:
Tropical Medicine and Health. 37:125-128
Post-malaria neurological syndrome (PMNS) is a rare complication after the treatment of falciparum malaria. We describe a case of a 56-year-old man who developed ataxia, tremor, and confusion 16 days after a successful treatment of falciparum malaria