Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Takashi Nirasawa"'
Autor:
Tatsuya Nakagawa, Naoki Okumura, Masaya Ikegawa, Yumiko Toyama, Takashi Nirasawa, Frederic Mascarelli, Hanielle Vaitinadapoule, Ines Aouimeur, Zhiguo He, Philippe Gain, Gilles Thuret, Noriko Koizumi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Fuchs endothelial corneal dystrophy (FECD) is a slowly evolving, bilateral disease of the corneal endothelium, characterized by an abnormal accumulation of extracellular matrix (ECM) in the basement membrane (Descemet’s membrane, DM). This
Externí odkaz:
https://doaj.org/article/8c59418b36a042c893cb972500c94ff7
Autor:
Hongsun Park, Tomoyuki Yamanaka, Yumiko Toyama, Atsushi Fujita, Hiroshi Doi, Takashi Nirasawa, Shigeo Murayama, Naomichi Matsumoto, Tomomi Shimogori, Masaya Ikegawa, Matti J. Haltia, Nobuyuki Nukina
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder, characterized by the presence of eosinophilic inclusions (NIIs) within nuclei of central and peripheral nervous system cells. This study aims to identify the com
Externí odkaz:
https://doaj.org/article/4f2888696a714b0ab7668db027d5f15c
Autor:
Nobuto Kakuda, Tomohiro Miyasaka, Noriyuki Iwasaki, Takashi Nirasawa, Satoko Wada-Kakuda, Junko Takahashi-Fujigasaki, Shigeo Murayama, Yasuo Ihara, Masaya Ikegawa
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-8 (2017)
Abstract Amyloid β (Aβ) deposition in the brain is an early and invariable feature of Alzheimer’s disease (AD). The Aβ peptides are composed of about 40 amino acids and are generated from amyloid precursor proteins (APP), by β- and γ-secretase
Externí odkaz:
https://doaj.org/article/4294eb132f5c41ccb8050b1ab2badd8b
Autor:
Hirofumi Enomoto, Takashi Nirasawa
Publikováno v:
Molecules, Vol 25, Iss 10, p 2373 (2020)
Flavan-3-ols, procyanidins and their monomers are major flavonoids present in peanuts that show a wide range of biological properties and health benefits, based on their potent antioxidant activity. Procyanidin oligomers, especially A-type, are repor
Externí odkaz:
https://doaj.org/article/10b87592299a4d048438a8d54a5832a3
Autor:
Kohta Iguchi, Etsuro Hatano, Takashi Nirasawa, Noriyuki Iwasaki, Motohiko Sato, Gen Yamamoto, Kenya Yamanaka, Tatsuya Okamoto, Yosuke Kasai, Naohiko Nakamura, Hiroaki Fuji, Tomohito Sakai, Nobuto Kakuda, Satoru Seo, Kojiro Taura, Kei Tashiro, Shinji Uemoto, Masaya Ikegawa
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0167647 (2017)
Liver regeneration after partial hepatectomy (PHx) is a time-dependent process, which is tightly regulated by multiple signaling cascades. Failure of this complex process leads to posthepatectomy liver failure (PHLF), which is associated with a high
Externí odkaz:
https://doaj.org/article/38fa4ee2483b45b08a5658356c986b82
Autor:
Masaya Ikegawa, Nobuto Kakuda, Tomohiro Miyasaka, Yumiko Toyama, Takashi Nirasawa, Karolina Minta, Jörg Hanrieder
Publikováno v:
Brain Connectivity.
Autor:
Eiji Sugiyama, Yuki Nishiya, Kenji Yamashita, Ryo Hirokawa, Yoshiteru Iinuma, Takashi Nirasawa, Hajime Mizuno, Yoshitaka Hamashima, Kenichiro Todoroki
A newly synthesized charged chiral tag enabled enantioselective imaging of D-, L-2-hydroxyglutaric acid, which are independently associated with the regulation of DNA methylation. The tag-conjugated diastereomers were ionized efficiently through MALD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdbed9595a6696872184d8ef942fe076
https://doi.org/10.26434/chemrxiv-2023-zt1r3-v2
https://doi.org/10.26434/chemrxiv-2023-zt1r3-v2
Autor:
Ryo Nakabayashi, Mai Uzaki, Kiminori Toyooka, Noriko Takeda-Kamiya, Kazuki Saito, Yutaka Yamada, Tetsuya Mori, Takashi Nirasawa
Publikováno v:
Plant Biotechnol (Tokyo)
Plants release specialized (secondary) metabolites from their roots to communicate with other organisms, including soil microorganisms. The spatial behavior of such metabolites around these roots can help us understand roles for the communication; ho
Autor:
Minoru Hirata, Shun-ichi Nagata, Mio Kikuchi, Kotono Nakamura, Aoi Ohnuma, Kei-ichi Hirota, Masaki Takasu, Hironaga Kakoi, Ho-Geun Kwak, Takashi Nirasawa, Kanichi Kusano, Taichiro Ishige, Hideaki Ishii, Teruaki Tozaki
Publikováno v:
Drug testing and analysisREFERENCES. 14(1)
In human and equestrian sporting events, one method of gene doping is the illegal use of therapeutic oligonucleotides to alter gene expression. In this study, we aimed to identify therapeutic oligonucleotides via sequencing using matrix-assisted lase
Autor:
Shinya Dohgu, Toshiro Matsui, Fuyuko Takata, Yasufumi Kataoka, Genki Komabayashi, Hayato Kiyohara, Takashi Nirasawa, Motohiro Maebuchi, Mitsuru Tanaka
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Apart from nutrients required for the brain, there has been no report that naturally occurring peptides can cross the blood-brain barrier (BBB). The aim of this study was to identify the BBB-transportable peptides using in situ mouse perfusion experi