Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Takashi Niimi"'
Publikováno v:
Respiration. 78:387-392
Background: The recently released handheld In-Check device can be used to measure the peak inspiratory flow rate (PIF) of patients and is reportedly useful in determining whether the PIF is sufficient for using inhaler devices. In this study, we eval
Autor:
Hideki Muramatsu, Yuko Takano, Mikinori Miyazaki, Shigeki Sato, Tetsuya Oguri, Hiroyuki Achiwa, Takashi Niimi, Hiroyoshi Maeda, Yuji Bessho, Ryuzo Ueda
Publikováno v:
Molecular Cancer Therapeutics. 5:1800-1806
We examined the expression levels of the multidrug resistance protein 5 (ABCC5) gene in non–small cell lung cancer (NSCLC) cell lines to clarify the relationship with the sensitivity to gemcitabine. The expression levels of ABCC5 were inversely cor
Autor:
Tetsuya Oguri, Hiroyuki Achiwa, Hideki Muramatsu, Hiroyoshi Maeda, Takashi Niimi, Ryuzo Ueda, Shigeki Sato, Yuji Bessho
Publikováno v:
Lung Cancer. 49:345-351
The expressions of thymidylate synthase (TS) and intracellular metabolic enzymes have been reported to be associated with the sensitivity and/or resistance to 5-fluorouracil (5-FU). However, since the role of these enzymes in the mechanism of resista
Autor:
Chunmei Li, Shinsuke Iida, Mitsunori Nishikawa, Mitsukuni Okabe, Ryuzo Ued, Hiroshi Inagaki, Takashi Niimi
Publikováno v:
International Journal of Hematology. 82:59-62
Mucosa-associated lymphoid tissue (MALT) lymphoma constitutes up to 90% of primary pulmonary lymphomas, but its diagnosis is often difficult. API2-MALT1 fusion is specific to MALT lymphoma and is detected in nearly half of the pulmonary cases. Cytolo
Publikováno v:
Haigan. 45:863-867
背景. 甲状腺癌ではしばしば肺末梢への転移, また気管への直接浸潤が認められるが, 気管支内転移を来す例は稀である. 症例. 症例は65歳男性. 5年前に当院で甲状腺癌 (乳頭腺癌) と診断さ
Autor:
Hiroyoshi Maeda, Ryuzo Ueda, Shigemitsu Ninomiya, Shigeki Sato, Haruhiko Kawaguchi, Kenji Akita, Hiroyuki Achiwa, Yoshitaka Fujii, Takashi Niimi, Shigeki Shimizu, Hiroshi Inagaki, Yosuke Yamakawa, Tadaaki Eimoto
Publikováno v:
Japanese Journal of Cancer Research : Gann
p185(HER-2/neu), a tyrosine kinase receptor, is one of the target molecules for cancer therapy, and its expression may reduce the sensitivity of tumor cells to anti-cancer drugs. p21(CIP1/WAF1) is a cyclin-dependent kinase inhibitor, and its expressi
Autor:
Takashi Niimi, Toshiyuki Mori, Hiroyoshi Maeda, Nobuo Ogisu, Haruhiko Kawaguchi, Yoshiki Sugiura, Kenji Akita, Y. Yamada, Ryuzo Ueda, Shigeki Sato
Publikováno v:
Internal Medicine. 40:201-207
Objective Soluble HLA class I antigens (sHLAs) in human serum have been reported to be associated with allografts and autoimmune disease and could modify immunological reactions induced by membrane type HLAs. To investigate the clinical significance
Autor:
Takashi Niimi, Yoshiki Sugiura, Ryuzo Ueda, Haruhiko Kawaguchi, Hiroyoshi Maeda, Shigeki Sato, Shigeo Mori
Publikováno v:
Chest. 118:923-927
Study objectives: The etiology of sarcoidosis remainsunknown, but recently it was reported that human herpesvirus 8 (HHV-8)may be detected in sarcoid tissue in a high proportion of patients. This study was performed to determine whether HHV-8 is impl
Autor:
Toshiyuki Mori, Shigeki Sato, H. Tomita, N. Ogisu, Takashi Niimi, Shigeki Shimizu, R. Matsuda
Publikováno v:
Respiratory Medicine. 92(12):1305-1310
Angiotensin-converting enzyme (ACE) inactivates bradykinin, substance P and neurokinin A, which are believed to play important roles in the pathogenesis of asthma, especially in neurogenic inflammation. It has recently been shown that an insertion (I
Autor:
Takashi Niimi
Publikováno v:
Haigan. 38:301-307
Interleukin 12 (IL-12) はThelper1型リンパ球の分化に決定的な役割をはたしている.抗腫瘍免疫反応においても, IL-12は重要な役割を演じていると考えられる.今回Lipopolysaccharide (LPS) とInterferon-γ (IF