Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Takashi Naganawa"'
1
Akademický článek
Stress history estimation of machine structure (A procedure for generating stress estimation equation using simulation and response surface)
Autor: Takashi ONOZATO, Saku EGAWA, Takeshi TAKAHASHI, Takayuki SHIMODAIRA, Takashi NAGANAWA
Publikováno v: Nihon Kikai Gakkai ronbunshu, Vol 82, Iss 843, Pp 16-00125-16-00125 (2016)
In this paper, we propose the method of estimating the stress history from the measured state quantity data from operating machine by creating a stress estimation equation for each evaluation point. We also report how to create the stress estimation
Externí odkaz: https://doaj.org/article/840493a37b4c43dc88eaa48e78e892ea
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2
Akademický článek
Establishment of unified fatigue design maps for different types of fracture mode of single-sided fillet welded T-joints
Autor: Yasuki KITA, Atsushi KITAGUCHI, Takashi NAGANAWA
Publikováno v: Nihon Kikai Gakkai ronbunshu, Vol 81, Iss 830, Pp 15-00113-15-00113 (2015)
Pure bending fatigue tests were conducted with single-sided fillet welded T-joint specimens. Two load conditions, which were given the tensile and compressive stresses in the weld toe, were applied, and fatigue strengths at 2×106 cycles were determi
Externí odkaz: https://doaj.org/article/ea546393759646edaa2a493a528d9cba
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4
Experimental Study to Verify Elliptical Confidence Limit Method for Bolted Joint Tightening
Autor: Soichi Hareyama, Takashi Naganawa, Ken-ichi Manabe, Takayuki Shimodaira
Publikováno v: Volume 2: Advanced Manufacturing.
The calibrated wrench method is often used for tightening. When tightening bolted joints, it is important to apply high axial tension. However, since the axial tension is indirectly applied in this method, it varies and has a distribution in the case
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2008bd72d8479222e80c89707f077f10
https://doi.org/10.1115/imece2016-66336
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6
Molecular mechanisms of TNF-α-induced ceramide formation in human glioma cells:P53-mediated oxidant stress-dependent and -independent pathways
Autor: Tohru Kiyono, Jun Shinoda, Motoshi Sawada, Toru Iwama, Shigeru Nakashima, Noboru Sakai, Shigeru Hara, Takashi Naganawa
Publikováno v: Cell Death & Differentiation. 11:997-1008
The present study was designed to examine the roles of p53, reactive oxygen species (ROS), and ceramide, and to determine their mutual relationships during tumor necrosis factor (TNF)-alpha-induced apoptosis of human glioma cells. In cells possessing
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d502f268483ece5735f19440fb00fb
https://doi.org/10.1038/sj.cdd.4401438
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7
SCID Mouse Model for Lethal Q Fever
Autor: Akitoyo Hotta, Katsuya Hirai, Hideto Fukushi, Toshiaki Masegi, Masako Andoh, Tsuyoshi Yamaguchi, Takashi Naganawa
Publikováno v: Infection and Immunity. 71:4717-4723
Q fever, a worldwide zoonosis caused byCoxiella burnetii, has many manifestations in humans. Endocarditis is the most serious complication of Q fever. Animal models are limited to acute pulmonary or hepatic disease and reproductive disorders. An appr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366ce0f1d0f79ce9c34c4f952c8d6dee
https://doi.org/10.1128/iai.71.8.4717-4723.2003
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8
Cell permeable ROS scavengers, Tiron and Tempol, rescue PC12 cell death caused by pyrogallol or hypoxia/reoxygenation
Autor: Shinichi Yoshimura, Masanori Nakagawa, Yasuhiko Kaku, Toru Iwama, Takashi Naganawa, Shigeru Nakashima, Yoshiko Banno, Shigeru Hara, Jun Yamada, Noboru Sakai, Motoshi Sawada, Haruki Yamakawa
Publikováno v: Neuroscience Research. 45:1-8
The role of superoxide anion (O(2)*-) in neuronal cell injury induced by reactive oxygen species (ROS) was examined in PC12 cells using pyrogallol (1,2,3-benzenetrior), a donor to release O(2)*-. Pyrogallol induced PC12 cell death at concentrations,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a70466ae8fce37deae9ebddbd77207
https://doi.org/10.1016/s0168-0102(02)00196-7
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9
Involvement of Phospholipase D in Sphingosine 1-Phosphate-induced Activation of Phosphatidylinositol 3-Kinase and Akt in Chinese Hamster Ovary Cells Overexpressing EDG3
Autor: Yoshuke Osawa, Hiroyuki Okamoto, Yoshinori Nozawa, Shigeru Nakashima, Pann-Ghill Suh, Takashi Naganawa, Yoshiko Banno, Yoh Takuwa, Yukihiro Akao
Publikováno v: Journal of Biological Chemistry. 276:35622-35628
Phospholipase D (PLD), phosphatidylinositol 3-kinase (PI3K), and Akt are known to be involved in cellular signaling related to proliferation and cell survival. In this report, we provide evidence that PLD links sphingosine 1-phosphate (S1P)-induced a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb967c992ecfc1c636ed13a1b403b1e
https://doi.org/10.1074/jbc.m105673200
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10
[Untitled]
Autor: Toru Iwama, Shinji Noda, Shinichi Yoshimura, Noboru Sakai, Shigeru Nakashima, Motoshi Sawada, Takashi Naganawa
Publikováno v: Journal of Neuro-Oncology. 52:11-21
Cisplatin is commonly used for the treatment of malignant brain tumors. However, the mechanisms of cell death by cisplatin are not fully understood. Therefore, the present study was designed to elucidate the apoptotic signaling pathway(s) activated b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10235bf7afeabbc946b47c062634dbff
https://doi.org/10.1023/a:1010624823158
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