Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Takashi Momoi"'
Autor:
Shinya Nakamura, Takuma Koyama, Naohiro Izawa, Seitaro Nomura, Takanori Fujita, Yasunori Omata, Takashi Minami, Morio Matsumoto, Masaya Nakamura, Eriko Fujita-Jimbo, Takashi Momoi, Takeshi Miyamoto, Hiroyuki Aburatani, Sakae Tanaka
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175632 (2017)
Trimethylation of histone H3 lysine 4 and lysine 27 (H3K4me3 and H3K27me3) at gene promoter regions critically regulates gene expression. Key developmental genes tend to exhibit changes in histone modification patterns from the H3K4me3/H3K27me3 bival
Externí odkaz:
https://doaj.org/article/25035f78986246198781dd29ab18eea8
Autor:
Eriko Fujita-Jimbo, Zhi-Ling Yu, Hong Li, Takanori Yamagata, Masato Mori, Takashi Momoi, Mariko Y Momoi
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51155 (2012)
Little is known about the molecular pathogenesis of Autism spectrum disorder (ASD), a neurodevelopmental disorder. Here we identified two mutations in the G-protein-coupled receptor 37 gene (GPR37) localized on chromosome 7q31-33, called the AUTS1 re
Externí odkaz:
https://doaj.org/article/d3718463a9d64d91883277772c1ef1bb
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30151 (2012)
Foxp2(R552H) knock-in (KI) mouse pups with a mutation related to human speech-language disorders exhibit poor development of cerebellar Purkinje cells and impaired ultrasonic vocalization (USV), a communication tool for mother-offspring interactions.
Externí odkaz:
https://doaj.org/article/e7b3142fbfb44d11876d85399d5795d3
Autor:
Hiroyoshi Ariga, Mizuo Maeda, Hideki Muto, Akira Kitamura, Makoto Miyazawa, Karin Sörgjerd, Tamotsu Zako, Yoshinori Itoo, Akira Abe, Hiroshi Kubota, Takashi Momoi, Sanae M.M. Iguchi-Ariga, Naofumi Terada, Masataka Kinjo, Erika Tashiro, Hirotake Kitaura
Publikováno v:
Journal of Biological Chemistry. 288(27):19958-19972
Huntington disease is caused by cell death after the expansion of polyglutamine (polyQ) tracts longer than ∼40 repeats encoded by exon 1 of the huntingtin (HTT) gene. Prefoldin is a molecular chaperone composed of six subunits, PFD1–6, and preven
Autor:
Daniela Salomon, Anya Vainshtein, Elena Kartvelishvily, Takashi Momoi, Helena Sabanay, Yael Eshed-Eisenbach, Katya Rechav, Galia Maik-Rachline, Neev Golan, Ivo Spiegel, Elior Peles, Shahar Frechter
Publikováno v:
Journal of Neuroscience. 33:10950-10961
The interaction between myelinating Schwann cells and the axons they ensheath is mediated by cell adhesion molecules of the Cadm/Necl/SynCAM family. This family consists of four members: Cadm4/Necl4 and Cadm1/Necl2 are found in both glia and axons, w
Autor:
Hermann Lübbert, Takashi Momoi, Yoshihiro Mezaki, Eriko Fujita, Yuko Tanabe, Yukiko K. Hayashi, Haruki Senoo, Xin-Ran Zhu
Publikováno v:
Cell Biology International. 37:731-736
RA175/SynCAM1/Cadm1 (Cadm1), a member of the immunoglobulin superfamily, is a synaptic cell adhesion molecule that has a PDZ-binding motif at the C-terminal region. It promotes the formation of presynaptic terminals and induces functional synapses in
Publikováno v:
Journal of Neurochemistry, Vol. 123, No 5 (2012) pp. 886-94
Mutations in the synaptic adhesion protein CADM1 (RA175/SynCAM1) are associated with autism spectrum disorder (ASD), a neurodevelopmental disorder of uncertain molecular origin. Cadm1-knock out (KO) mice exhibit smaller cerebella with decreased numbe
Publikováno v:
Cerebral cortex (New York, N.Y. : 1991). 27(7)
The molecular mechanisms underlying the formation of the thalamus during development have been investigated intensively. Although transcription factors distinguishing the thalamic primordium from adjacent brain structures have been uncovered, those i
Autor:
Eriko Fujita, Shigeki Yuasa, Yuko Tanabe, Yuji Fujiwara, Tadashi Kasahara, Ayumi Matsuzaki, Takashi Momoi
Publikováno v:
Journal of Neurochemistry. 122:72-80
J. Neurochem. (2012) 122, 72–80. Abstract FOXP2, a forkhead box-containing transcription factor, forms homo- or hetero-dimers with FOXP family members and localizes to the nucleus, while FOXP2(R553H), which contains a mutation related to speech/lan
Publikováno v:
Biochemical and Biophysical Research Communications. 410:593-596
FOXP2 is a forkhead box-containing transcription factor with several recognizable sequence motifs. However, little is known about the FOXP2-associated proteins except for C-terminal binding protein (CtBP). In the present study, we attempted to isolat