Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Takashi Mikawa"'
Publikováno v:
eLife, Vol 12 (2024)
Large-scale cell flow characterizes gastrulation in animal development. In amniote gastrulation, particularly in avian gastrula, a bilateral vortex-like counter-rotating cell flow, called ‘polonaise movements’, appears along the midline. Here, th
Externí odkaz:
https://doaj.org/article/cde381aff74c4c58baf08e4b956a2966
Autor:
Jan Schlueter, Takashi Mikawa
Publikováno v:
Cell Reports, Vol 24, Iss 6, Pp 1456-1463 (2018)
Summary: The body cavity is a space where internal organs develop and are placed. Despite the importance of this internal space, how the body cavity forms specifically within the mesoderm remains largely unknown. Here, we report that upon the onset o
Externí odkaz:
https://doaj.org/article/982c0c5d1a734112af346452639b4883
Autor:
Michael Bressan, Trevor Henley, Jonathan D. Louie, Gary Liu, Danos Christodoulou, Xue Bai, Joan Taylor, Christine E. Seidman, J.G. Seidman, Takashi Mikawa
Publikováno v:
Cell Reports, Vol 23, Iss 8, Pp 2283-2291 (2018)
Summary: Impulses generated by a multicellular, bioelectric signaling center termed the sinoatrial node (SAN) stimulate the rhythmic contraction of the heart. The SAN consists of a network of electrochemically oscillating pacemaker cells encased in a
Externí odkaz:
https://doaj.org/article/25a556a02d6c4211bd398d8f560b1591
Publikováno v:
Journal of Developmental Biology, Vol 1, Iss 2, Pp 82-91 (2013)
The proepicardium is a transient extracardiac embryonic tissue that gives rise to the epicardium and a number of coronary vascular cell lineages. This important extracardiac tissue develops through multiple steps of inductive events, from specificati
Externí odkaz:
https://doaj.org/article/d6182433ef994f8ab084ff9373c43542
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115207 (2014)
Anomalous action potential conduction through the atrial chambers of the heart can lead to severe cardiac arrhythmia. To date, however, little is known regarding the mechanisms that pattern proper atrial conduction during development. Here we demonst
Externí odkaz:
https://doaj.org/article/2023f848a0bb4eff869508455b59f755
Autor:
Catherine Czeisler, Takashi Mikawa
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75833 (2013)
VEGF signaling is a key regulator of vessel formation and function. In vascular endothelial cells, this signaling is mediated through its cognate receptor VEGFR2, which is dynamically sorted in response to ligand. Little is known about the underlying
Externí odkaz:
https://doaj.org/article/28614c4f61ad4a0b96910346acc330ff
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61422 (2013)
In the mature eye, three distinct tissue fates, retina, ciliary body, and iris, arrange with a strict linear organization along the central (back) to peripheral (front) axis. The establishment of this topographical relationship within the optic vesic
Externí odkaz:
https://doaj.org/article/2c79b57257104d00ac641f21b008f6d6
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13689 (2010)
The notochord is a signaling center required for the patterning of the vertebrate embryonic midline, however, the molecular and cellular mechanisms involved in the formation of this essential embryonic tissue remain unclear. The urochordate Ciona int
Externí odkaz:
https://doaj.org/article/d50e23ea5be74ea6bf119c9b400bede9
Publikováno v:
bioRxiv
SummaryLarge-scale cell flow characterizes gastrulation in animal development. In amniote gastrulation, a bilateral vortex-like counter-rotating cell flow, called ‘polonaise movements’, appears along the midline. Here, through experimental manipu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965d865385ff439185439a50d54eb887
https://europepmc.org/articles/PMC10245986/
https://europepmc.org/articles/PMC10245986/
Publikováno v:
bioRxiv
Individual homologous chromosomes are spatially segregated into haploid chromosome sets along the centrosome axis in an antipairing configuration. Disruption of the antipairing pattern occurs in cancer cells. However, little is known about how this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b230897842b5a15e14464d1aa5527e2e
https://europepmc.org/articles/PMC10081237/
https://europepmc.org/articles/PMC10081237/