Výsledky vyhledávání - "Takashi Makabe"

Recombinant Fusion Polypeptide with Cell‐ and Heparin‐binding Domains of Fibronectin Inhibits Liver Metastasis of L5178Y‐ML25 Lymphoma Cells

Autor: Fusao Kimizuka, Ikunoshin Kato, Harue Okuyama, Yukuo Ishizaki, Yoshihiro Matsumoto, Takashi Makabe, Jun Murata, Junya Yoneda, Ichiro Azuma, Ikuo Saiki

Publikováno v: Japanese Journal of Cancer Research : Gann

We have investigated the effect of recombinant polypeptides with cell‐binding domain (C‐274) or with heparin‐binding domain (H‐271) and their fusion polypeptide (CH‐271) on liver metastasis of murine lymphoid tumor. The polypeptides contain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd459f50d06a8f3cf0685d96babced1
http://europepmc.org/articles/PMC5918250

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Inhibition of Tumor Angiogenesis by a Synthetic Cell-adhesive Polypeptide Containing the Arg-Gly-Asp (RGD) Sequence of Fibronectin, Poly(RGD)

Autor: Takashi Makabe, Ikuo Saiki, Jun Murata, Seiichi Tokura, Ichiro Azuma, Norio Nishi

Publikováno v: Japanese Journal of Cancer Research. 81:668-675

We have investigated the anti‐angiogenic effect of a polymeric peptide based on the Arg‐Gly‐Asp (RGD) core sequence of fibronectin as a monomer unit, i.e., poly(RGD), in syngeneic mice and in vitro. Single intratumoral administration of poly(RG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046302b739b2049a9c0e260bc4fcfc4e
https://doi.org/10.1111/j.1349-7006.1990.tb02625.x

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Inhibition of Tumor-Induced Angiogenesis by Sulfated Chitin Derivatives

Autor: Seiichi Tokura, Ikuo Saiki, Jun Murata, Takashi Makabe, Yasuhiro Tsuta, Ichiro Azuma

Publikováno v: Advances in Chitin and Chitosan ISBN: 9789401159449

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97d6c3c62c61bc8fa84ace57612a004d
https://doi.org/10.1007/978-94-011-5942-5_12

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Inhibitory effect of antimetastatic fusion polypeptide of human fibronectin on tumor cell adhesion to extracellular matrices

Autor: Yukuo Ishizaki, Takashi Makabe, Ichiro Azuma, Junya Yoneda, Fusao Kimizuka, Ikunoshin Kato, Ikuo Saiki, Jun Murata, Yoshihiro Matsumoto

Publikováno v: Japanese Journal of Cancer Research : Gann

We investigated the inhibitory mechanism of liver metastasis by using recombinant fragments with cell- and/or heparin-binding domains (C-274, H-271 or the fusion fragment CH-271). Intravenous co-injection of L5178Y-ML25 cells with CH-271 was more eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d736a7b13cef72807048528d2b1a31
https://pubmed.ncbi.nlm.nih.gov/1955380

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Inhibitory effect of fibronectin and its recombinant polypeptides on the adhesion of metastatic melanoma cells to laminin

Autor: Takashi Makabe, Junya Yoneda, Ikuo Saiki, Ichiro Azuma, Jun Murata, Ikunoshin Kato, Fusao Kimizuka, Yukuo Ishizaki

Publikováno v: Japanese Journal of Cancer Research : Gann

We have utilized recombinant fibronectin fragments with cell-binding domain (C-274), heparin-binding domain (H-271) or CS1 peptide in type III connecting segment (IIICS) and their fusion polypeptides such as CH-296 (containing C-274, H-271 and CS1),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67e3770111db670bb63bf1c914807d1
https://pubmed.ncbi.nlm.nih.gov/1955378

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Inhibition of lung metastasis by synthetic and recombinant fragments of human fibronectin with functional domains

Autor: Ichiro Azuma, Yoshihiro Matsumoto, Ikunoshin Kato, Yasutoshi Kawase, Jun Murata, Yoichi Ohdate, Ikuo Saiki, Yuki Taguchi, Tomoko Shimojo, Fusao Kimizuka, Takashi Makabe

Publikováno v: Japanese Journal of Cancer Research : Gann

We have investigated the antimetastatic effect of synthetic or recombinant peptides containing the functional domains of fibronectin on experimental and spontaneous lung metastases of murine tumor cells. CS1 peptide which is present within type III h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e51102d0677e6d49d2b1c6e47cc6da
https://pubmed.ncbi.nlm.nih.gov/2121673

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Modulation of haptotactic migration of metastatic melanoma cells by the interaction between heparin and heparin-binding domain of fibronectin

Autor: Takashi Makabe, Yuki Taguchi, F Kimizuka, Yasutoshi Kawase, I. Kato, Ikuo Saiki, Jun Murata, Ichiro Azuma, Yoichi Ohdate, Tomoko Shimojo

Publikováno v: The Journal of biological chemistry. 265(24)

We utilized recombinant fibronectin polypeptides with cell-binding domain and heparin-binding domains (referred to as C-274 and H-271, respectively) and their fusion polypeptide (CH-271) to examine the role of sulfated polysaccharide heparin and/or t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d1b8fb869c07d537421f8ee7cce3e8d
https://pubmed.ncbi.nlm.nih.gov/2387848

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