Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Takashi MASAOKA"'
Autor:
Angela Corona, Rita Meleddu, Francesca Esposito, Simona Distinto, Giulia Bianco, Takashi Masaoka, Elias Maccioni, Luis Menéndez-Arias, Stefano Alcaro, Stuart F J Le Grice, Enzo Tramontano
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147225 (2016)
The DNA polymerase and ribonuclease H (RNase H) activities of human immunodeficiency virus type 1 (HIV-1) are needed for the replication of the viral genome and are validated drug targets. However, there are no approved drugs inhibiting RNase H and t
Externí odkaz:
https://doaj.org/article/d990758b6bec47228f7c81f5c7d4f13a
Autor:
Mayumi Imahashi, Taisuke Izumi, Dai Watanabe, Junji Imamura, Kazuhiro Matsuoka, Hirotaka Ode, Takashi Masaoka, Kei Sato, Noriyo Kaneko, Seiichi Ichikawa, Yoshio Koyanagi, Akifumi Takaori-Kondo, Makoto Utsumi, Yoshiyuki Yokomaku, Takuma Shirasaka, Wataru Sugiura, Yasumasa Iwatani, Tomoki Naoe
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92861 (2014)
The human APOBEC3 family of proteins potently restricts HIV-1 replication APOBEC3B, one of the family genes, is frequently deleted in human populations. Two previous studies reached inconsistent conclusions regarding the effects of APOBEC3B loss on H
Externí odkaz:
https://doaj.org/article/19720746eac84b04a1c0496c7b1b7b26
Autor:
Anna Y. Lynn, John A. Beutler, Stuart F. J. Le Grice, Keith E. Aron, Ryan P. Murelli, Vickie Marshall, Anqi Xia, Liang Tang, Danielle R. Hirsch, Elena M. Cornejo Castro, Jennifer T. Miller, Haiyan Zhao, Brittany Varnado, Kaivon Kouhestani, Denise Whitby, Takashi Masaoka
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
Kaposi's sarcoma-associated herpesvirus (KSHV), the etiological agent of Kaposi's sarcoma, belongs to the Herpesviridae family, whose members employ a multicomponent terminase to resolve nonparametric viral DNA into genome-length units prior to their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ec203297a298c6624baf31a9da2703
https://doi.org/10.1128/aac.00233-18
https://doi.org/10.1128/aac.00233-18
Autor:
John A. Beutler, Takashi Masaoka, Baofeng Zhang, Rajat K. Pal, Michael P. D'Erasmo, Christine Meck, Jennifer A. Wilson, Danielle R. Hirsch, Stuart F.J. Le Grice, Emilio Gallicchio, Ryan P. Murelli
Publikováno v:
MedChemComm. 7:1783-1788
HIV Reverse Transcriptase-associated ribonuclease H activity is a promising enzymatic target for drug development that has not been successfully targeted in the clinic. While the α-hydroxytropolone-containing natural products β-thujaplicinol and ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea992066e20109c2362f02ab54c9f6e
https://doi.org/10.1039/c6md00238b
https://doi.org/10.1039/c6md00238b
Autor:
John A. Beutler, Takashi Masaoka, Jennifer A. Wilson, Errol M. Hunte, Stuart F. J. Le Grice, Ryan P. Murelli, Michael P. D'Erasmo
Publikováno v:
MedChemComm. 7:1789-1792
α-Hydroxytropolones are established inhibitors of several therapeutically relevant binuclear metalloenzymes, and thus lead drug targets for various human diseases. We have leveraged a recently-disclosed three-component oxidopyrylium cycloaddition in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b2b9865ea3ac3541d77efff5a5b33e
https://doi.org/10.1039/c6md00237d
https://doi.org/10.1039/c6md00237d
Autor:
Alexander J. Krynitsky, Clark D. Ridge, Eugene P. Mazzola, Takashi Masaoka, Jennifer A. Wilson, John A. Beutler, Erich Grundel, Jun Ma, Rahul S. Pawar, Stuart F.J. Le Grice
Publikováno v:
J Nat Prod
Two new sesquiterpenoid tropolone glycosides, liriosmasides A (1) and B (2), along with two known compounds, secoxyloganin and oplopanpheside C, were isolated from a methanol extract of the roots of Liriosma ovata. The structures of 1 and 2 were eluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b2d634abcb473080b6a285c7802a0d
https://doi.org/10.1021/np5006696
https://doi.org/10.1021/np5006696
Publikováno v:
Journal of Japan Society of Civil Engineers, Ser. B1 (Hydraulic Engineering). 76:I_1273-I_1278
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5fcffcef4348773c6673f074fb74253
https://doi.org/10.2208/jscejhe.76.2_i_1273
https://doi.org/10.2208/jscejhe.76.2_i_1273
Publikováno v:
Journal of Japan Society of Civil Engineers, Ser. B3 (Ocean Engineering). 76:I_810-I_815
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c509ea16c815e1fc4bb85209c09a44a
https://doi.org/10.2208/jscejoe.76.2_i_810
https://doi.org/10.2208/jscejoe.76.2_i_810
Publikováno v:
Journal of Japan Society of Civil Engineers, Ser. B2 (Coastal Engineering). 75:I_1093-I_1098
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22242404376e5c3e31dadace9dcacf2c
https://doi.org/10.2208/kaigan.75.i_1093
https://doi.org/10.2208/kaigan.75.i_1093
Autor:
Oriana Tabarrini, Violetta Cecchetti, Enzo Tramontano, Christophe Pannecouque, Angela Corona, Elias Maccioni, Giuseppe Manfroni, Francesca Esposito, Jenny Desantis, Stefano Sabatini, Serena Massari, Stuart F. J. Le Grice, Simona Distinto, Takashi Masaoka
Despite the significant progress achieved with combination antiretroviral therapy in the fight against human immunodeficiency virus (HIV) infection, the difficulty to eradicate the virus together with the rapid emergence of multidrug-resistant strain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31960d3d0881195d62a2767fa91df64d
http://hdl.handle.net/11391/1388251
http://hdl.handle.net/11391/1388251
