Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Takashi Kozaka"'
Autor:
Taro Yamashita, Tuyen Thuy Bich Ho, Alessandro Nasti, Takuya Komura, Hiiro Inui, Takashi Kozaka, Yoji Kitamura, Kazuhiro Shiba, Tatsuya Yamashita, Kazunori Kawaguchi, Masao Honda, Yoshio Sakai
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Pancreatic ductular adenocarcinoma (PDAC) is among the most dreadful of malignancies, in part due to the lack of efficacious chemotherapy. Immune checkpoint inhibitors, including anti-programmed cell death 1 (anti-PD-1) antibodies, are nov
Externí odkaz:
https://doaj.org/article/dd84f869e3cc48479cd658abe21133d9
Autor:
Izumi Uno, Takashi Kozaka, Daisuke Miwa, Yoji Kitamura, Mohammad Anwar-Ul Azim, Kazuma Ogawa, Junichi Taki, Seigo Kinuya, Kazuhiro Shiba
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146719 (2016)
PURPOSE:To develop a superior VAChT imaging probe for SPECT, radiolabeled (-)-OIDV and (+)-OIDV were isolated and investigated for differences in their binding affinity and selectivity to VAChT, as well as their in vivo activities. PROCEDURES:Radioio
Externí odkaz:
https://doaj.org/article/862b14d59e374085b7750bc06354c85f
Autor:
Hiroshi Wakabayashi, Hiroshi Mori, Tomo Hiromasa, Norihito Akatani, Anri Inaki, Takashi Kozaka, Yoji Kitamura, Kazuma Ogawa, Seigo Kinuya, Junichi Taki
Publikováno v:
Journal of Nuclear Cardiology. 30:653-661
Autor:
Takashi Kozaka, Junichi Taki, Norihito Akatani, Hiroshi Wakabayashi, Hiroshi Mori, Kazuhiro Shiba, Anri Inaki, Tomo Hiromasa, Kazuma Ogawa, Seigo Kinuya
Publikováno v:
Circulation Journal. 85:2102-2108
金沢大学疾患モデル総合研究センター
Background: This study chronologically evaluated the expression of the intensity and distribution of the sigma-1 receptor (σ1R) demonstrated by radiolabeled 2-[4-(2-iodophenyl)piperidino]cyclo
Background: This study chronologically evaluated the expression of the intensity and distribution of the sigma-1 receptor (σ1R) demonstrated by radiolabeled 2-[4-(2-iodophenyl)piperidino]cyclo
Autor:
Kazuma Ogawa, Seigo Kinuya, Kazuhiro Shiba, Takashi Kozaka, Yoji Kitamura, Junichi Taki, Taiki Shigeno
Publikováno v:
Annals of Nuclear Medicine. 35:167-175
We investigated the characteristics of radio-iodinated 2-[4-(2-iodophenyl)piperidino]cyclopentanol (OI5V) as a single photon emission computed tomography (SPECT) ligand for mapping sigma-1 receptor (σ-1R), which plays an important role in stress rem
Autor:
Taiki, Shigeno, Takashi, Kozaka, Yoji, Kitamura, Kazuma, Ogawa, Junichi, Taki, Seigo, Kinuya, Kazuhiro, Shiba
Publikováno v:
Annals of nuclear medicine. 35(2)
We investigated the characteristics of radio-iodinated 2-[4-(2-iodophenyl)piperidino]cyclopentanol (OI5V) as a single photon emission computed tomography (SPECT) ligand for mapping sigma-1 receptor (σ-1R), which plays an important role in stress rem
Autor:
Daisuke Miwa, Junichi Taki, Kazuhiro Shiba, Yoji Kitamura, Seigo Kinuya, Taiki Shigeno, Takashi Kozaka, Kazuma Ogawa
Publikováno v:
Synapse.
To develop a PET imaging agent to visualize brain cholinergic neurons and synaptic changes caused by Alzheimer's disease, (-)- and (+)-o-[11 C]methyl-trans-decalinvesamicol ([11 C]OMDV) were isolated and investigated for differences in not only their
Autor:
Daisuke, Miwa, Yoji, Kitamura, Takashi, Kozaka, Taiki, Shigeno, Kazuma, Ogawa, Junichi, Taki, Seigo, Kinuya, Kazuhiro, Shiba
Publikováno v:
Synapse (New York, N.Y.)REFERENCES. 74(11)
To develop a PET imaging agent to visualize brain cholinergic neurons and synaptic changes caused by Alzheimer's disease, (-)- and (+)-o-[
Autor:
Mengfei Wang, Seigo Kinuya, Akira Odani, Ryohei Masuda, Kenji Mishiro, Kazuhiro Shiba, Kazuma Ogawa, Takashi Kozaka
Publikováno v:
Bioorganicmedicinal chemistry. 27(10)
Sigma-1 receptor imaging probes for determining the expression levels are desirable for diagnoses of various diseases and companion diagnoses of therapeutic agents targeting the sigma-1 receptor. In this study, we aimed to develop probes with higher
Autor:
Kahuhiro Shiba, Izumi Uno, Mohammad Anwar ul Azim, Yoji Kitamura, Daisuke Miwa, Takashi Kozaka, Kazuma Ogawa
Publikováno v:
Bangladesh Journal of Nuclear Medicine. 17:97-102
Introduction: In cholinergic neurons, high affinity choline uptake (HACU) by the high affinity choline transporter (HAChT) is a rate-limiting and regulatory step for the synthesis of Acetylcholine (Ach).Thus, HAChT appear to be a relatively specific