Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Takashi Kamimura"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
RNA-targeted small molecules are a promising modality in drug discovery. Recently, we found that a fluoroquinolone derivative, KG022, can bind to RNAs with bulged C or G. To clarify the RNA specificity of KG022, we analyzed the effect of the base pai
Externí odkaz:
https://doaj.org/article/962e9e99b825479ab40423c3bf74cb16
Publikováno v:
The Journal of Biochemistry. 171:239-244
Interaction analysis between small molecules and RNA as well as structure determination of RNA–small molecule complexes will be the clues to search for compounds that bind to specific mRNA or non-coding RNA in drug discovery. In this study, the RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db19bec946987d911439972f6df45101
https://doi.org/10.1093/jb/mvab124
https://doi.org/10.1093/jb/mvab124
Autor:
Takashi Kamimura, Ken Muramatsu
Publikováno v:
International Journal of Physical Therapy & Rehabilitation. 4
In an attempt to evaluate central and peripheral contributions to muscle fatigue, changes in force development and electromyographic (EMG) signal after sustained isometric plantar flexion (IPF) were examined. Sustained IPF of maximal effort was conti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7863f7c2364a96465bec754c6ba9ab9b
https://doi.org/10.15344/2455-7498/2018/146
https://doi.org/10.15344/2455-7498/2018/146
Publikováno v:
Journal of Synchrotron Radiation
1/2SLPI is a C-terminal domain of SLPI (secretory leukocyte protease inhibitor) which inhibits various serine proteases broadly. The present study is the first X-ray structural report on how 1/2SLPI with P1 Leu strongly inhibits trypsin and how it ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278852b935fafc8679f97d9d4da56550
https://doi.org/10.1107/s090904951302133x
https://doi.org/10.1107/s090904951302133x
Autor:
Takashi Kamimura, Masanori Nagai, Sei-Ichi Sasaki, Ken Muramatsu, Tomoyasu Ishiguro, Masatoshi Niwa
Publikováno v:
Neuroscience Letters. 531:109-113
Alterations in the number and size of motoneurons were studied in the medial gastrocnemius (MG) motor nucleus of diabetic rats (12 or 22 weeks after injection of storeptozotocin) and age-matched controls. Each group contained 6 animals. MG motoneuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c887dce95103a67557ea5c53963b9c3
https://doi.org/10.1016/j.neulet.2012.10.031
https://doi.org/10.1016/j.neulet.2012.10.031
Publikováno v:
International Journal of Physical Therapy & Rehabilitation. 2
In the coherence analysis of muscles, beta bands of 15-35 Hz were reflecting activation of corticospinal tract (CST). The purpose of this study was to investigate the participation of activation of CST during dual task walking by electromyography (EM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::518f4172a930d78da97fa3b3a3c88082
https://doi.org/10.15344/2455-7498/2016/119
https://doi.org/10.15344/2455-7498/2016/119
Publikováno v:
Human Movement Science. 28:407-414
The effects of isometric antagonist conditioning contraction (ACC) at various durations and intensities on the contractile force, electromyographic (EMG) amplitude, and their rates of rise of elbow flexor muscles were examined in healthy participants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ffc837f5977f7da3a3cd443eeecc7b5
https://doi.org/10.1016/j.humov.2009.02.005
https://doi.org/10.1016/j.humov.2009.02.005
Publikováno v:
Journal of Synchrotron Radiation
The 1/2SLPI and HNE complex structure was solved at 1.7 Å resolution and compared with the interaction mechanism of elafin.
SLPI (secretory leukocyte protease inhibitor) is a 107-residue non-glycosylated protease inhibitor, which inhibits a wid
SLPI (secretory leukocyte protease inhibitor) is a 107-residue non-glycosylated protease inhibitor, which inhibits a wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d385876fa9525fc464b06c41e0cb7a97
https://doi.org/10.1107/s0909049507060670
https://doi.org/10.1107/s0909049507060670
Autor:
Tsutomu Hamuro, Sadaaki Iwanaga, Hiroshi Kido, Yujiro Asada, Kinta Hatakeyama, Youichi Kunori, Shintaro Kamei, Takashi Kamimura, Yuushi Okumura
Publikováno v:
FEBS Journal. 274:3065-3077
Tissue factor pathway inhibitor (TFPI) is a multivalent Kunitz-type protease inhibitor that primarily inhibits the extrinsic pathway of blood coagulation. It is synthesized by various cells and its expression level increases in inflammatory environme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bb92b8814962a264c5e544e5e720cba
https://doi.org/10.1111/j.1742-4658.2007.05833.x
https://doi.org/10.1111/j.1742-4658.2007.05833.x
Publikováno v:
Life Sciences. 78:3051-3057
Tumor necrosis factor-alpha (TNF-alpha) is a potent multifunctional cytokine that plays a central role in the pathogenesis of many inflammatory diseases. Interleukin-8 (IL-8) is a principle neutrophil chemoattractant and activator in humans. The alve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f415cd98fd311b666918039b382f9fd
https://doi.org/10.1016/j.lfs.2005.12.023
https://doi.org/10.1016/j.lfs.2005.12.023